PDB ID: 4LM3
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Structure summary
Code : | 4LM3 PDBj RCSB PDB PDBe | ||||||||||||
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Header : | HYDROLASE/HYDROLASE INHIBITOR | ||||||||||||
Title : | Crystal structure of PDE10A2 with fragment ZT464 | ||||||||||||
Release Data : | 2014-02-26 | ||||||||||||
Compound : |
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Authors : | Sridhar, V., Badger, J., Logan, C., Chie-Leon, B., Nienaber, V. | ||||||||||||
Keywords : | fragment screening, hydrolase, HYDROLASE-HYDROLASE INHIBITOR complex | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.49 Å ) | ||||||||||||
Citation : |
Identification and Optimization of PDE10A Inhibitors Using Fragment-Based Screening by Nanocalorimetry and X-ray Crystallography.
Recht, M.I.,Sridhar, V.,Badger, J.
et al.
PubMed: 24375910 |
Reaction
Chain : | A, B | ||||||||||||||||
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UniProt : | Q9Y233 (PDE10_HUMAN) | ||||||||||||||||
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