Het-PDB Navi2 (PDB: 7VOX)

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Ligands
Code	Name		Style	Show	Link
MG	Magnesium ion				PoSSuM

Non-standard Residues
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Glycosylation
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Download interaction data: 7VOX

Code :

7VOX PDBj RCSB PDB PDBe

Header :

TRANSCRIPTION/DNA

Title :

The crystal structure of human forkhead box protein A in complex with DNA 2

Release Data :

2022-08-17

Compound :

mol_id	molecule	chains
1	DNA (5'-D(PTPCPGPAPTPAPAPTPAPAPAPTPAPTPTPT)-3')	D,F

mol_id	molecule	chains
2	DNA (5'-D(PAPAPAPTPAPTPTPTPAPTPTPAPTPCPGPA)-3')	E,G

mol_id	molecule	chains	synonym
3	Hepatocyte nuclear factor 3-alpha	A,B,C,H	HNF-3-alpha,HNF-3A,Forkhead box protein A1,Transcription factor 3A,TCF-3A

Source :

mol_id	organism_scientific	organism_common
1	Homo sapiens (taxid:9606)	Human
	synthetic: yes

mol_id	organism_scientific	organism_common
2	Homo sapiens (taxid:9606)	Human
	synthetic: yes

mol_id	organism_scientific	organism_common	expression_system
3	Homo sapiens (taxid:9606)	Human	Escherichia coli (taxid:562)
	gene: FOXA1, HNF3A, TCF3A

Authors :

Choi, Y., Yoon, H.J., Lee, H.H.

Keywords :

DNA-protein complex, transcription factor, TRANSCRIPTION, TRANSCRIPTION-DNA complex

Exp. method :

X-RAY DIFFRACTION ( 2.1000 Å )

Citation :

FOXL2 and FOXA1 cooperatively assemble on the TP53 promoter in alternative dimer configurations.

Choi, Y.,Luo, Y.,Lee, S. et al.
(2022) Nucleic Acids Res. 50 : 8929 - 8946

PDB ID: 7VOX