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Modified Residues
Code Name Link
0DA 2'-deoxy-L-ribo-furanosyl adenosine-5'-monophosphate
0DC 2'-deoxy-L-ribo-furanosyl cytosine-5'-monophosphate
0DG 2'-deoxy-L-ribo-furanosyl guanine-5'-monophosphate
0DT 2'-deoxy-L-ribo-furanosyl thymidine-5'-monophosphate
Code : 6L97   PDBj   RCSB PDB   PDBe
Header : DNA BINDING PROTEIN/DNA
Title : Complex of DNA polymerase IV and L-DNA duplex
Release Data : 2020-07-08
Compound :
mol_id molecule chains synonym
1 DNA polymerase IV A,B Pol IV
ec: 2.7.7.7
mol_id molecule chains
2 DNA (5'-D(P*(0DG)P*(0DG)P*(0DA)P*(0DA)P*(0DT)P*(0DC)P*(0DC)P*(0DT)P*(0DT)P*(0DC)P*(0DC)P*(0DC)P*(0DC)P*(0DC))-3') T
mol_id molecule chains
3 DNA (5'-D(*(0DG)P*(0DG)P*(0DG)P*(0DG)P*(0DG)P*(0DA)P*(0DA)P*(0DG)P*(0DG)P*(0DA)P*(0DT)P*(0DT)P*(0DC)P*(0DC))-3') P
Source :
mol_id organism_scientific expression_system
1 Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)  (taxid:273057) Escherichia coli  (taxid:562)
strain: ATCC 35092 / DSM 1617 / JCM 11322 / P2
gene: dbh, dpo4, SSO2448
mol_id organism_scientific
2 Synthetic construct  (taxid:32630)
synthetic: yes
mol_id organism_scientific
3 Synthetic construct  (taxid:32630)
synthetic: yes
Authors : Chung, H.S., An, J., Hwang, D.
Keywords : Dpo4, L-DNA duplex, DNA polymerase, DNA BINDING PROTEIN, DNA BINDING PROTEIN-DNA complex
Exp. method : X-RAY DIFFRACTION ( 2.3620 Å )
Citation :

The crystal structure of a natural DNA polymerase complexed with mirror DNA.

An, J.,Choi, J.,Hwang, D.  et al.
(2020)  Chem.Commun.(Camb.)  56 : 2186 - 2189

PubMed: 31971182
DOI: 10.1039/c9cc09351f

Chain : A, B
UniProt : Q97W02 (DPO4_SACS2)
Reaction : Reaction=a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1); Xref=Rhea:RHEA:22508, Rhea:RHEA-COMP:11130, Rhea:RHEA-COMP:11131, ChEBI:CHEBI:33019, ChEBI:CHEBI:61560, ChEBI:CHEBI:83828; EC=2.7.7.7;