Brand  (β version)

PDB ID: 6J0I

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Ligands
Code Name Style Show Link
CRH 1,2-hydro-1-oxy-3,4-hydro-3-(1-methoxy-2-oxy-3,4-dihydroxypentyl)-8,9-dihyroxy-7-methylanthracene PoSSuM
CO Cobalt (II) ion PoSSuM
ARI (2r,3r,6r)-6-hydroxy-2-methyltetrahydro-2h-pyran-3-yl acetate PoSSuM
1GL 2,6-dideoxy-4-O-methyl-alpha-D-galactopyranose PoSSuM
CDR (2r,5s,6r)-6-methyltetrahydro-2h-pyran-2,5-diol PoSSuM
ERI 3-C-methyl-4-O-acetyl-alpha-L-olivopyranose PoSSuM
: Polysaccharide
Non-standard Residues
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Structure summary

Code : 6J0I   PDBj   RCSB PDB   PDBe
Header : DNA/ANTIBIOTIC
Title : Structure of [Co2+-(Chromomycin A3)2]-D(TTGGCGAA)2 complex
Release Data : 2019-07-24
Compound :
mol_id molecule chains
1 DNA (5'-D(*TP*TP*GP*GP*CP*GP*AP*A)-3') A,B,C,D,E,F
Source :
mol_id organism_scientific
1 Synthetic construct  (taxid:32630)
synthetic: yes
Authors : Satange, R.B., Chuang, C.Y., Hou, M.H.
Keywords : Mismatch DNA, Chromomycin A3, Drug-DNA complex, G:G mismatch, DNA-ANTIBIOTIC complex
Exp. method : X-RAY DIFFRACTION ( 2.5000 Å )
Citation :

Polymorphic G:G mismatches act as hotspots for inducing right-handed Z DNA by DNA intercalation.

Satange, R.,Chuang, C.Y.,Neidle, S.  et al.
(2019)  Nucleic Acids Res.  47 : 8899 - 8912

PubMed: 31361900
DOI: 10.1093/nar/gkz653