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Code Name Link
FT7 1-[(2,4-difluorophenyl)methyl]-2,3-dimethyl-N-[(1r)-1-phenylpropyl]-1h-indole-5-carboxamide
Code : 6D3E   PDBj   RCSB PDB   PDBe
Title : PPARg LBD in Complex with SR1988
Release Data : 2019-02-27
Compound :
mol_id molecule chains synonym
1 Peroxisome proliferator-activated receptor gamma A,B PPAR-gamma,Nuclear receptor subfamily 1 group C member 3
fragment: Ligand Binding Domain
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:469008)
gene: PPARG, NR1C3
expression_system_strain: BL21(DE3)
Authors : Frkic, R.L., Bruning, J.B.
Keywords : type 2 diabetes, nuclear receptor, drug discovery, TRANSCRIPTION
Exp. method : X-RAY DIFFRACTION ( 2.3950 Å )
Citation :

Structural and Dynamic Elucidation of a Non-acid PPARgammaPartial Agonist: SR1988.

Frkic, R.L.,Chua, B.S.,Shin, Y.  et al.
(2018)  Nucl Receptor Res  5

PubMed: 30906767
DOI: 10.11131/2018/101350

Chain : A, B
UniProt : P37231 (PPARG_HUMAN)
Reaction : -