Brand  (β version)

PDB ID: 5NXC

Hetero Atom Contents

  The number of atoms exceeds 100,000.
  So, it can not be displayed here.

Select unit:

Select hetatm:   

close
information
centroid:
interaction residue:

Select chain:   Sequence  

Data format:   

Color scheme of protein:

Ligands
Code Name Style Show Link
9DB (2~{R})-2-azanyl-2-cyclohexyl-~{N}-[2-(1-methylpyrazol-4-yl)-9-oxidanylidene-3,10,11-triazatricyclo[6.4.1.0^{4,13}]trideca-1,4,6,8(13),11-pentaen-6-yl]ethanamide PoSSuM
Non-standard Residues
Code Name Show
Glycosylation
Code Name Emphasize
Modification
Code Name Show

Structure summary

Code : 5NXC   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : LIM Domain Kinase 1 (LIMK1) In Complex With PF-00477736
Release Data : 2017-05-24
Compound :
mol_id molecule chains synonym
1 LIM domain kinase 1 L LIMK-1
ec: 2.7.11.1
fragment: UNP residues 330-637
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Spodoptera frugiperda  (taxid:7108)
gene: LIMK1, LIMK
Authors : Mathea, S., Salah, E., Pike, A.C.W., Bushell, S., Carpenter, E.P., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Bullock, A.N., Knapp, S.
Keywords : Kinase Actin cytoskeleton Inhibitor, transferase
Exp. method : X-RAY DIFFRACTION ( 2.25 Å )
Citation :

LIM Domain Kinase (LIMK1) In Complex With PF-00477736

Mathea, S.,Salah, E.,Pike, A.C.W.  et al.
To Be Published 

Reaction

Chain : L
UniProt : P53667 (LIMK1_HUMAN)
Reaction: EC: Evidence:
Physiological Direction:
L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+) 2.7.11.1 PubMed:22328514
left-to-right
L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+) 2.7.11.1 PubMed:22328514
left-to-right