PDB ID: 4HVD
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Structure summary
Code : | 4HVD PDBj RCSB PDB PDBe | ||||||||||||
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Header : | Transferase/Transferase Inhibitor | ||||||||||||
Title : | JAK3 kinase domain in complex with 2-Cyclopropyl-5H-pyrrolo[2,3-B]pyrazine-7-carboxylic acid ((S)-1,2,2-trimethyl-propyl)-amide | ||||||||||||
Release Data : | 2013-01-16 | ||||||||||||
Compound : |
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Source : |
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Authors : | Kuglstatter, A., Shao, A. | ||||||||||||
Keywords : | Kinase-Inhibitor Complex, Transferase-Transferase Inhibitor complex | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.85 Å ) | ||||||||||||
Citation : |
3-Amido Pyrrolopyrazine JAK Kinase Inhibitors: Development of a JAK3 vs JAK1 Selective Inhibitor and Evaluation in Cellular and in Vivo Models.
Soth, M.,Hermann, J.C.,Yee, C.
et al.
PubMed: 23214979 |
Reaction
Chain : | A | ||||||||
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UniProt : | P52333 (JAK3_HUMAN) | ||||||||
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