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Ligands
Code Name Style Show Link
FVX Fluvoxamine
NA Sodium ion
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Code : 4MM9   PDBj   RCSB PDB   PDBe
Header : TRANSPORT PROTEIN
Title : Crystal structure of LeuBAT (delta13 mutant) in complex with fluvoxamine
Release Data : 2013-10-16
Compound :
mol_id molecule chains
1 Transporter A
mutation: N21Y, G24D, I106S, T254S, S256G, A261V, I262L, Y265F, E290S, I359G, P362G, G408T, T409G
Source :
mol_id organism_scientific expression_system
1 Aquifex aeolicus  (taxid:224324) Escherichia coli  (taxid:562)
strain: VF5
gene: snf, aq_2077
Authors : Wang, H., Gouaux, E.
Keywords : transporter, TRANSPORT PROTEIN
Exp. method : X-RAY DIFFRACTION ( 2.900 Å )
Citation :

Structural basis for action by diverse antidepressants on biogenic amine transporters.

Wang, H.,Goehring, A.,Wang, K.H.  et al.
(2013)  Nature  503 : 141 - 145

PubMed: 24121440
DOI: 10.1038/nature12648

Chain : A
UniProt : O67854 (O67854_AQUAE)
Reaction : -