PDB ID: 4F7N
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Structure summary
Code : | 4F7N PDBj RCSB PDB PDBe | ||||||||||||||||||||||||
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Header : | TRANSFERASE/TRANSCRIPTION/INHIBITOR | ||||||||||||||||||||||||
Title : | Crystal structure of human CDK8/CYCC in complex with compound 11 (1-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-3-(5-hydroxypentyl)urea) | ||||||||||||||||||||||||
Release Data : | 2013-05-01 | ||||||||||||||||||||||||
Compound : |
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Source : |
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Authors : | Schneider, E.V., Boettcher, J., Huber, R., Maskos, K. | ||||||||||||||||||||||||
Keywords : | protein kinase complex, Proteros, TRANSFERASE-TRANSCRIPTION-INHIBITOR complex | ||||||||||||||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.65 Å ) | ||||||||||||||||||||||||
Citation : |
Structure-kinetic relationship study of CDK8/CycC specific compounds.
Schneider, E.V.,Bottcher, J.,Huber, R.
et al.
PubMed: 23630251 |
Reaction
Chain : | A | ||||||||||||||||
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UniProt : | P49336 (CDK8_HUMAN) | ||||||||||||||||
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Chain : | B |
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UniProt : | P24863 (CCNC_HUMAN) |
Reaction : | - |