PDB ID: 4D9M
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Structure summary
Code : | 4D9M PDBj RCSB PDB PDBe | ||||||||||||
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Header : | LYASE | ||||||||||||
Title : | Crystal structure of Diaminopropionate ammonia lyase from Escherichia coli in complex with aminoacrylate-PLP azomethine reaction intermediate | ||||||||||||
Release Data : | 2012-04-25 | ||||||||||||
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Authors : | Bisht, S., Rajaram, V., Bharath, S.R., Murthy, M.R.N. | ||||||||||||
Keywords : | Fold type II PLP-dependent enzyme, Tryptophan synthase beta subunit-like PLP-dependent enzymes superfamily, Lyase | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.50 Å ) | ||||||||||||
Citation : |
Crystal Structure of Escherichia coli Diaminopropionate Ammonia-lyase Reveals Mechanism of Enzyme Activation and Catalysis
Bisht, S.,Rajaram, V.,Bharath, S.R.
et al.
PubMed: 22505717 |
Reaction
Chain : | A, B |
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UniProt : | P66899 (DPAL_ECOLI) |
Reaction : | Reaction=(S)-2,3-diaminopropanoate + H(+) + H2O = 2 NH4(+) + pyruvate; Xref=Rhea:RHEA:22084, ChEBI:CHEBI:15361, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:28938, ChEBI:CHEBI:57721; EC=4.3.1.15; Evidence={ECO:0000269|PubMed:12596860}; Reaction=(R)-2,3-diaminopropanoate + H(+) + H2O = 2 NH4(+) + pyruvate; Xref=Rhea:RHEA:52432, ChEBI:CHEBI:15361, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:28938, ChEBI:CHEBI:136599; EC=4.3.1.15; Evidence={ECO:0000269|PubMed:12596860}; |