PDB ID: 3UXM
Hetero Atom Contents
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Structure summary
Code : | 3UXM PDBj RCSB PDB PDBe | ||||||||||||
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Header : | TRANSFERASE/TRANSFERASE INHIBITOR | ||||||||||||
Title : | Structure Guided Development of Novel Thymidine Mimetics targeting Pseudomonas aeruginosa Thymidylate Kinase: from Hit to Lead Generation | ||||||||||||
Release Data : | 2012-02-01 | ||||||||||||
Compound : |
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Source : |
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Authors : | Choi, J.Y., Plummer, M.S., Starr, J., Desbonnet, C.R., Soutter, H.H., Chang, J., Miller, J.R., Dillman, K., Miller, A.A., Roush, W.R. | ||||||||||||
Keywords : | Thymidylate kinase, thymidine triphosphate, TRANSFERASE-TRANSFERASE INHIBITOR complex | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.95 Å ) | ||||||||||||
Citation : |
Structure guided development of novel thymidine mimetics targeting Pseudomonas aeruginosa thymidylate kinase: from hit to lead generation.
Choi, J.Y.,Plummer, M.S.,Starr, J.
et al.
PubMed: 22243413 |
Reaction
Chain : | A, B, C, D |
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UniProt : | Q9HZN8 (KTHY_PSEAE) |
Reaction : | Reaction=ATP + dTMP = ADP + dTDP; Xref=Rhea:RHEA:13517, ChEBI:CHEBI:30616, ChEBI:CHEBI:58369, ChEBI:CHEBI:63528, ChEBI:CHEBI:456216; EC=2.7.4.9; |