Het-PDB Navi2 (PDB: 3TKC)

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Ligands
Code	Name		Style	Show	Link
FMV	(1s,3r,5z,7e,14beta,17alpha,20s)-20-[5-(1-hydroxy-1-methylethyl)furan-2-yl]-9,10-secopregna-5,7,10-triene-1,3-diol				PoSSuM
SO4	Sulfate ion				PoSSuM

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Download interaction data: 3TKC

Code :

3TKC PDBj RCSB PDB PDBe

Header :

TRANSCRIPTION

Title :

Design, Synthesis, Evaluation and Structure of Vitamin D Analogues with Furan Side Chains

Release Data :

2012-03-07

Compound :

mol_id	molecule	chains	synonym
1	Vitamin D3 receptor	A	VDR, 1,25-dihydroxyvitamin D3 receptor, Nuclear receptor subfamily 1 group I member 1

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Escherichia coli (taxid:562)
	gene: VDR, NR1I1

Authors :

Huet, T., Moras, D., Rochel, N.

Keywords :

alpha-helical sandwich, transcription, calcitriol, phosphorylation, nucleus

Exp. method :

X-RAY DIFFRACTION ( 1.750 Å )

Citation :

Design, synthesis, evaluation, and structure of vitamin D analogues with furan side chains.

Fraga, R.,Zacconi, F.,Sussman, F. et al.
(2012) Chemistry 18 : 603 - 612

PDB ID: 3TKC