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Code Name Link
MG Magnesium ion
SR Strontium ion
Modified Residues
Code Name Link
AF2 2'-deoxy-2'-fluoroadenosine 5'-(dihydrogen phosphate)
CFZ 2'-deoxy-2'-fluorocytidine 5'-(dihydrogen phosphate)
GF2 2'-deoxy-2'-fluoroguanosine 5'-(dihydrogen phosphate)
UFT 2'-deoxy-2'-fluorouridine 5'-(dihydrogen phosphate)
Code : 3P4A   PDBj   RCSB PDB   PDBe
Header : RNA
Title : 2'Fluoro modified RNA octamer fA2U2
Release Data : 2011-01-05
Compound :
mol_id molecule chains
1 2'Fluoro modified RNA 8-MER A,B,C,D,E,F
Source :
mol_id organism_scientific
synthetic: yes
other_details: Chemically synthesized modified RNA
Authors : Manoharan, M., Akinc, A., Pandey, R.K., Qin, J., Hadwiger, P., John, M., Mills, K., Charisse, K., Maier, M.A., Nechev, L., Greene, E.M., Pallan, P.S., Rozners, E., Rajeev, K.G., Egli, M.
Keywords : RNA, 2'-FLUORO-RNA, O2'-MODIFICATION, OCTAMER, 2'-fluoro 2'-deoxycytidine, 2'-fluoro 2'-deoxyguanosine, 2'-fluoro 2'-deoxyadenosine, 2'-fluoro 2'-deoxyuridine, siRNA
Exp. method : X-RAY DIFFRACTION ( 1.20 Å )
Citation :

Unexpected origins of the enhanced pairing affinity of 2'-fluoro-modified RNA.

Pallan, P.S.,Greene, E.M.,Jicman, P.A.  et al.
(2011)  Nucleic Acids Res.  39 : 3482 - 3495

PubMed: 21183463
DOI: 10.1093/nar/gkq1270