Het-PDB Navi2 (PDB: 2KWG)

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Ligands
Code	Name		Style	Show	Link

Non-standard Residues
Code	Name	Show
A2M	2'-O-methyladenosine 5'-(dihydrogen phosphate)
AF2	2'-deoxy-2'-fluoroadenosine 5'-(dihydrogen phosphate)
CFZ	2'-deoxy-2'-fluorocytidine 5'-(dihydrogen phosphate)
GF2	2'-deoxy-2'-fluoroguanosine 5'-(dihydrogen phosphate)
OMC	O2'-methylycytidine-5'-monophosphate
OMG	O2'-methylguanosine-5'-monophosphate
OMU	O2'-methyluridine 5'-monophosphate
UFT	2'-deoxy-2'-fluorouridine 5'-(dihydrogen phosphate)

Glycosylation
Code	Name	Emphasize

Modification
Code	Name	Show

Download interaction data: 2KWG

Code :

2KWG PDBj RCSB PDB PDBe

Header :

RNA

Title :

Solution structure of a fully modified 2'-F/2'-OMe siRNA construct

Release Data :

2010-07-21

Compound :

mol_id	molecule	chains
1	5'-R((GF2)P(OMG)P(GF2)P(OMU)P(AF2)P(A2M)P(AF2)P(OMU)P(AF2)P(OMC)P(AF2)P(OMU)P(UFT)P(OMC)P(UFT)P(OMU)P(CFZ)P(A2M)P(UFT)P(OMU)P*(UFT))-3'	A

mol_id	molecule	chains
2	5'-R(P(A2M)P(UFT)P(OMG)P(AF2)P(A2M)P(GF2)P(A2M)P(AF2)P(OMU)P(GF2)P(OMU)P(AF2)P(OMU)P(UFT)P(OMU)P(AF2)P(OMC)P(CFZ)P(OMC)P(UFT)P*(OMU))-3'	B

Source :

mol_id	organism_scientific
1
	synthetic: yes

mol_id	organism_scientific
2
	synthetic: yes

Authors :

Podbevsek, P., Bhat, B., Plavec, J.

Keywords :

siRNA, 2'-fluoro, 2'-O-methyl, RNA

Exp. method :

SOLUTION NMR

Citation :

Solution-state structure of a fully alternately 2'-F/2'-OMe modified 42-nt dimeric siRNA construct.

Podbevsek, P.,Allerson, C.R.,Bhat, B. et al.
(2010) Nucleic Acids Res. 38 : 7298 - 7307

PDB ID: 2KWG