Het-PDB Navi2 (PDB: 1ZEI)

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Ligands
Code	Name	Link
CL	Chloride ion	PoSSuM
CRS	M-cresol	PoSSuM
ZN	Zinc ion	PoSSuM

Non-standard Residues
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Glycosylation
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Download interaction data: 1ZEI

Code :

1ZEI PDBj RCSB PDB PDBe

Header :

HORMONE

Title :

CROSS-LINKED B28 ASP INSULIN

Release Data :

1999-02-16

Compound :

mol_id	molecule	chains	synonym
1	INSULIN	A,B,C,D,E,F	B28ASP-X-MCR
	mutation: P28D

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Sus scrofa (taxid:9823)	Pig	Saccharomyces cerevisiae (taxid:4932)
	expression_system_common: Baker's yeast

Authors :

Whittingham, J.L., Edwards, E.J., Antson, A.A., Clarkson, J.M., Dodson, G.G.

Keywords :

HORMONE, METABOLIC ROLE, CHEMICAL ACTIVITY, INSULIN MUTANT, CROSS-LINK, GLUCOSE METABOLISM, DIABETES

Exp. method :

X-RAY DIFFRACTION ( 1.9 Å )

Citation :

Interactions of phenol and m-cresol in the insulin hexamer, and their effect on the association properties of B28 pro --> Asp insulin analogues.

Whittingham, J.L.,Edwards, D.J.,Antson, A.A. et al.
(1998) Biochemistry 37 : 11516 - 11523

Role of C-Terminal B-Chain Residues in Insulin Assembly: The Structure of Hexameric Lysb28Prob29-Human Insulin

Ciszak, E.,Beals, J.M.,Frank, B.H. et al.
(1995) Structure 3 : 615

The Structure of a Rhombohedral R6 Insulin Hexamer that Binds Phenol

Smith, G.D.,Dodson, G.G.
(1992) Biopolymers 32 : 441

PDB ID: 1ZEI