Brand  (β version)

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Ligands
Code Name Link
HDZ Nitrogen molecule
Modified Residues
Code Name Link
0AF 7-hydroxy-L-tryptophan
Code : 1MAF   PDBj   RCSB PDB   PDBe
Header : OXIDOREDUCTASE(CHNH2(D)-DEAMINATING)
Title : The Active Site Structure of Methylamine Dehydrogenase: Hydrazines Identify C6 as the Reactive Site of the Tryptophan Derived Quinone Cofactor
Release Data : 1994-01-31
Compound :
mol_id molecule chains
1 METHYLAMINE DEHYDROGENASE (LIGHT SUBUNIT) L
ec: 1.4.99.3
mol_id molecule chains
2 METHYLAMINE DEHYDROGENASE (HEAVY SUBUNIT) H
ec: 1.4.99.3
Source :
mol_id organism_scientific
1 Paracoccus versutus  (taxid:34007)
mol_id organism_scientific
2 Paracoccus versutus  (taxid:34007)
Authors : Huizinga, E.G., Vellieux, F.M.D., Hol, W.G.J.
Keywords : OXIDOREDUCTASE(CHNH2(D)-DEAMINATING)
Exp. method : X-RAY DIFFRACTION ( 2.6 Å )
Citation :

Active site structure of methylamine dehydrogenase: hydrazines identify C6 as the reactive site of the tryptophan-derived quinone cofactor.

Huizinga, E.G.,van Zanten, B.A.,Duine, J.A.  et al.
(1992)  Biochemistry  31 : 9789 - 9795

PubMed: 1390754
DOI: 10.1021/bi00155a036

Crystallographic Investigations of the Tryptophan-Derived Cofactor in the Quinoprotein Methylamine Dehydrogenase

Chen, L.,Mathews, F.S.,Davidson, V.L.  et al.
(1991)  FEBS Lett.  287 : 163

Structure of Quinoprotein Methylamine Dehydrogenase at 2.25 Angstroms Resolution

Vellieux, F.M.D.,Huitema, F.,Groendijk, H.  et al.
(1989)  Embo J.  8 : 2171

Purification, Crystallization and Preliminary X-Ray Investigation of Quinoprotein Methylamine Dehydrogenase from Thiobacillus Versutus

Vellieux, F.M.D.,Frank, J.,Swarte, M.B.A.  et al.
(1986)  Eur.J.Biochem.  154 : 383

Chain : L
UniProt : P22641 (DHML_PARVE)
Reaction : Reaction=H2O + methylamine + 2 oxidized [amicyanin] = formaldehyde + 2 H(+) + NH4(+) + 2 reduced [amicyanin]; Xref=Rhea:RHEA:30207, Rhea:RHEA-COMP:11100, Rhea:RHEA-COMP:11101, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:16842, ChEBI:CHEBI:28938, ChEBI:CHEBI:29036, ChEBI:CHEBI:49552, ChEBI:CHEBI:59338; EC=1.4.9.1;
Chain : H
UniProt : P23006 (DHMH_PARVE)
Reaction : Reaction=H2O + methylamine + 2 oxidized [amicyanin] = formaldehyde + 2 H(+) + NH4(+) + 2 reduced [amicyanin]; Xref=Rhea:RHEA:30207, Rhea:RHEA-COMP:11100, Rhea:RHEA-COMP:11101, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:16842, ChEBI:CHEBI:28938, ChEBI:CHEBI:29036, ChEBI:CHEBI:49552, ChEBI:CHEBI:59338; EC=1.4.9.1;