PDB ID: 1KHP
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Structure summary
Code : | 1KHP PDBj RCSB PDB PDBe | ||||||||||||||||||||
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Header : | HYDROLASE/HYDROLASE INHIBITOR | ||||||||||||||||||||
Title : | Monoclinic form of papain/ZLFG-DAM covalent complex | ||||||||||||||||||||
Release Data : | 2003-09-09 | ||||||||||||||||||||
Compound : |
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Source : |
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Authors : | Janowski, R., Kozak, M., Jankowska, E., Grzonka, Z., Jaskolski, M. | ||||||||||||||||||||
Keywords : | PROTEASE INHIBITOR, DIAZOMETHYLKETONE INHIBITOR, IRREVERSIBLE INHIBITOR, HYDROLASE-HYDROLASE INHIBITOR COMPLEX | ||||||||||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.0 Å ) | ||||||||||||||||||||
Citation : |
Two polymorphs of a covalent complex between papain and a diazomethylketone inhibitor
Janowski, R.,Kozak, M.,Jankowska, E.
et al.
PubMed: 15357669 Crystallization and preliminary crystallographic studies of a new crystal form of papain from Carica papaya.
Kozak, M.,Kozian, E.,Grzonka, Z.
et al.
Structural studies of cysteine proteases and their inhibitors
Grzonka, Z.,Jankowska, E.,Wieczerzak, E.
et al.
Binding of chloromethyl ketone substrate analogues to crystalline papain.
Drenth, J.,Kalk, K.H.,Swen, H.M.
Structure of monoclinic papain at 1.60 Angstroms resolution.
Pickersgill, R.W.,Harris, G.W.,Garman, E.
Binding modes of a new epoxysuccinyl-peptide inhibitor of cysteine proteases. Where and how do cysteine proteases express their selectivity?
Czaplewski, C.,Grzonka, Z.,Jaskolski, M.
et al.
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Reaction
Chain : | A | ||||||||
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UniProt : | P00784 (PAPA1_CARPA) | ||||||||
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