Brand  (β version)

PDB ID: 1AD4

Hetero Atom Contents

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain: Hide other chain(s)

Ligands
Code Name Link
HH2 6-hydroxymethylpterin-diphosphate PoSSuM
K Potassium ion PoSSuM
MN Manganese (II) ion PoSSuM

Structure summary

Code : 1AD4   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : DIHYDROPTEROATE SYNTHETASE COMPLEXED WITH OH-CH2-PTERIN-PYROPHOSPHATE FROM STAPHYLOCOCCUS AUREUS
Release Data : 1998-04-29
Compound :
mol_id molecule chains synonym
1 DIHYDROPTEROATE SYNTHETASE A,B DHPS
ec: 2.5.1.15
Source :
mol_id organism_scientific
1 Staphylococcus aureus  (taxid:1280)
Authors : Oefner, C., Kostrewa, D.
Keywords : TRANSFERASE, SYNTHETASE, DIHYDROPTEROATE SYNTHETASE
Exp. method : X-RAY DIFFRACTION ( 2.4 Å )
Citation :

Structure and function of the dihydropteroate synthase from Staphylococcus aureus.

Hampele, I.C.,D'Arcy, A.,Dale, G.E.  et al.
(1997)  J.Mol.Biol.  268 : 21 - 30

PubMed: 9149138
DOI: 10.1006/jmbi.1997.0944

Reaction

Chain : A, B
UniProt : O05701 (DHPS_STAAU)
Reaction : Reaction=(7,8-dihydropterin-6-yl)methyl diphosphate + 4-aminobenzoate = 7,8-dihydropteroate + diphosphate; Xref=Rhea:RHEA:19949, ChEBI:CHEBI:17836, ChEBI:CHEBI:17839, ChEBI:CHEBI:33019, ChEBI:CHEBI:72950; EC=2.5.1.15; Evidence={ECO:0000269|PubMed:9149138};