Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain:

Ligands
Code Name Link
MN Manganese (II) ion
PO4 Phosphate ion
Code : 1A6Q   PDBj   RCSB PDB   PDBe
Header : HYDROLASE
Title : CRYSTAL STRUCTURE OF THE PROTEIN SERINE/THREONINE PHOSPHATASE 2C AT 2 A RESOLUTION
Release Data : 1998-05-27
Compound :
mol_id molecule chains
1 PHOSPHATASE 2C A
ec: 3.1.3.16
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
Authors : Das, A.K., Helps, N.R., Cohen, P.T.W., Barford, D.
Keywords : CATALYTIC MECHANISM, METALLOENZYME, PROTEIN PHOSPHATASE 2C, SIGNAL TRANSDUCTUIN, HYDROLASE
Exp. method : X-RAY DIFFRACTION ( 2.0 Å )
Citation :

Crystal structure of the protein serine/threonine phosphatase 2C at 2.0 A resolution.

Das, A.K.,Helps, N.R.,Cohen, P.T.  et al.
(1996)  EMBO J.  15 : 6798 - 6809

PubMed: 9003755

Chain : A
UniProt : P35813 (PPM1A_HUMAN)
Reaction : Reaction=H2O + O-phospho-L-seryl-[protein] = L-seryl-[protein] + phosphate; Xref=Rhea:RHEA:20629, Rhea:RHEA-COMP:9863, Rhea:RHEA- COMP:11604, ChEBI:CHEBI:15377, ChEBI:CHEBI:29999, ChEBI:CHEBI:43474, ChEBI:CHEBI:83421; EC=3.1.3.16; Evidence={ECO:0000255|PROSITE- ProRule:PRU01082};
Reaction=H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate; Xref=Rhea:RHEA:47004, Rhea:RHEA-COMP:11060, Rhea:RHEA- COMP:11605, ChEBI:CHEBI:15377, ChEBI:CHEBI:30013, ChEBI:CHEBI:43474, ChEBI:CHEBI:61977; EC=3.1.3.16; Evidence={ECO:0000269|PubMed:30267671};