Brand  (β version)

PDB ID: 1A3W

Hetero Atom Contents

color scheme of protein:

hetatm:

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information
centroid:
interaction residue:

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Ligands
Code Name Link
FBP 1,6-di-O-phosphono-beta-D-fructofuranose PoSSuM
K Potassium ion PoSSuM
MN Manganese (II) ion PoSSuM
PGA 2-phosphoglycolic acid PoSSuM

Structure summary

Code : 1A3W   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : PYRUVATE KINASE FROM SACCHAROMYCES CEREVISIAE COMPLEXED WITH FBP, PG, MN2+ AND K+
Release Data : 1998-05-27
Compound :
mol_id molecule chains
1 PYRUVATE KINASE A,B
ec: 2.7.1.40
Source :
mol_id organism_scientific organism_common
1 Saccharomyces cerevisiae  (taxid:4932) Baker's yeast
Authors : Jurica, M.S., Mesecar, A., Heath, P.J., Shi, W., Nowak, T., Stoddard, B.L.
Keywords : PYRUVATE KINASE, ALLOSTERIC REGULATION, TRANFERASE, TRANSFERASE
Exp. method : X-RAY DIFFRACTION ( 3.0 Å )
Citation :

The allosteric regulation of pyruvate kinase by fructose-1,6-bisphosphate.

Jurica, M.S.,Mesecar, A.,Heath, P.J.  et al.
(1998)  Structure  6 : 195 - 210

PubMed: 9519410
DOI: 10.1016/S0969-2126(98)00021-5

Reaction

Chain : A, B
UniProt : P00549 (KPYK1_YEAST)
Reaction : Reaction=ATP + pyruvate = ADP + H(+) + phosphoenolpyruvate; Xref=Rhea:RHEA:18157, ChEBI:CHEBI:15361, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:58702, ChEBI:CHEBI:456216; EC=2.7.1.40; Evidence={ECO:0000269|PubMed:10413488};