Brand  (β version)

PDB ID: 1A31

Hetero Atom Contents

  The number of atoms exceeds 100,000.
  So, it can not be displayed here.

Select unit:

Select chain:   Sequence  

Data format:   

Color scheme of protein:

Ligands
Code Name Style Show Link
Non-standard Residues
Code Name Show
5IU 5-iodo-2'-deoxyuridine-5'-monophosphate
PTR O-phosphotyrosine
Glycosylation
Code Name Emphasize
Modification
Code Name Show

Structure summary

Code : 1A31   PDBj   RCSB PDB   PDBe
Header : ISOMERASE/DNA
Title : HUMAN RECONSTITUTED DNA TOPOISOMERASE I IN COVALENT COMPLEX WITH A 22 BASE PAIR DNA DUPLEX
Release Data : 1998-08-28
Compound :
mol_id molecule chains
1 DNA (5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*5IUP*5IU*TP*GP*AP*AP*AP*AP*AP*5IUP*5IUP*5IUP*5IUP*T)-3') C
mol_id molecule chains
2 DNA (5'-D(*AP*AP*AP*AP*AP*TP*5IUP*5IUP*5IUP*5IUP*CP*AP*AP*AP*GP*TP*CP*TP*TP*TP*TP*T)-3') D
mol_id molecule chains
3 PROTEIN (TOPOISOMERASE I) A
ec: 5.99.1.2
fragment: CORE DOMAIN AND C-TERMINAL DOMAIN
Source :
mol_id organism_scientific
1
synthetic: yes
mol_id organism_scientific
2
synthetic: yes
mol_id organism_scientific organism_common expression_system
3 Homo sapiens  (taxid:9606) Human Spodoptera frugiperda  (taxid:7108)
cellular_location: NUCLEUS
expression_system_common: Fall armyworm
expression_system_vector: BACULOVIRUS
Authors : Redinbo, M.R., Stewart, L., Kuhn, P., Champoux, J.J., Hol, W.G.J.
Keywords : TOPOISOMERASE I/DNA, DNA, TOPOISOMERASE I, ISOMERASE-DNA COMPLEX
Exp. method : X-RAY DIFFRACTION ( 2.1 Å )
Citation :

Crystal structures of human topoisomerase I in covalent and noncovalent complexes with DNA.

Redinbo, M.R.,Stewart, L.,Kuhn, P.  et al.
(1998)  Science  279 : 1504 - 1513

PubMed: 9488644
DOI: 10.1126/science.279.5356.1504

Reaction

Chain : A
UniProt : ?
Reaction : -