Brand  (β version)

PDB ID: 17GS

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Ligands
Code Name Style Show Link
GTX S-hexylglutathione PoSSuM
MES 2-(N-morpholino)-ethanesulfonic acid PoSSuM
Non-standard Residues
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Glycosylation
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Structure summary

Code : 17GS   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : GLUTATHIONE S-TRANSFERASE P1-1
Release Data : 1998-12-30
Compound :
mol_id molecule chains synonym
1 GLUTATHIONE S-TRANSFERASE A,B GSTP1-1
ec: 2.5.1.18
mutation: K54A
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
cellular_location: CYTOSOL
gene: GSTP1
expression_system_gene: GSTP1
Authors : Oakley, A.J., Lo Bello, M., Parker, M.W.
Keywords : GLUTATHIONE TRANSFERASE, K54A MUTANT, DETOXIFICATION, TRANSFERASE
Exp. method : X-RAY DIFFRACTION ( 1.90 Å )
Citation :

Glutathione S-transferase P1-1

Oakley, A.J.,Lo Bello, M.,Parker, M.W.
To be published 

Reaction

Chain : A, B
UniProt : P09211 (GSTP1_HUMAN)
Reaction: EC: Evidence:
Physiological Direction:
RX + glutathione = an S-substituted glutathione + a halide anion + H(+) 2.5.1.18 PubMed:1540159, PubMed:1567427, PubMed:8433974
left-to-right ECO:0000305
prostaglandin J2 + glutathione = prostaglandin J2-S-(R)- glutathione - PubMed:9084911
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prostaglandin J2 + glutathione = prostaglandin J2-S-(S)- glutathione - PubMed:9084911
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prostaglandin A2 + glutathione = prostaglandin A2-S-(S)- glutathione - PubMed:9084911
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11(S)-hydroxy-14(S),15(S)-epoxy-(5Z,8Z,12E)-eicosatrienoate + glutathione = (11S,15S)-dihydroxy-14(R)-S-glutathionyl-(5Z,8Z,12E)- eicosatrienoate - PubMed:21046276
left-to-right