PDB ID: 6QXS
Hetero Atom Contents
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Data format:
Color scheme of protein:
Code | Name | Style | Show | Link | |
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UFP | 5-fluoro-2'-deoxyuridine-5'-monophosphate | PoSSuM | |||
SO4 | Sulfate ion | PoSSuM | |||
FFO | N-[4-({[(6s)-2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid | PoSSuM |
Code | Name | Show |
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CME | S,S-(2-hydroxyethyl)thiocysteine |
Code | Name | Emphasize |
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Code | Name | Show |
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Download interaction data: 6QXS
Structure summary
Code : | 6QXS PDBj RCSB PDB PDBe | ||||||||||||||||||||||||
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Header : | TRANSFERASE | ||||||||||||||||||||||||
Title : | Crystal structure of Enteroccocus faecalis thymidylate synthase (EfTS) in complex with FdUMP | ||||||||||||||||||||||||
Release Data : | 2019-04-10 | ||||||||||||||||||||||||
Compound : |
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Authors : | Pozzi, C., Mangani, M. | ||||||||||||||||||||||||
Keywords : | Enteroccocus faecalis thymidylate synthase, EfTS, folate pathway, inhibitor, FdUMP, TRANSFERASE | ||||||||||||||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.88 Å ) | ||||||||||||||||||||||||
Citation : |
Structural Comparison ofEnterococcus faecalisand Human Thymidylate Synthase Complexes with the Substrate dUMP and Its Analogue FdUMP Provides Hints about Enzyme Conformational Variabilities.
Pozzi, C.,Ferrari, S.,Luciani, R.
et al.
PubMed: 30935102 |
Reaction
Chain : | B, C, D | ||||||||
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UniProt : | Q834R3 (TYSY_ENTFA) | ||||||||
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