ID	6QXSA	STANDARD;	PRT;	315	AA.
DT	CONVERTED FROM PDB (SEQRES) 6QXS
DE	Thymidylate synthase
OS	Enterococcus faecalis (strain ATCC 700802 / V583)
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.880
CC	R-Factor	0.203
FT	#SUB	17	  17 	HIS	A	204	 204 	TYR	B	Protein	S	1
FT	#SUB	17	  17 	HIS	A	206	 206 	ASN	B	Protein	S	11
FT	#SUB	19	  19 	LYS	A	175	 175 	ASP	B	Protein	S	3
FT	#SUB	19	  19 	LYS	A	204	 204 	TYR	B	Protein	S	4
FT	#SUB	19	  19 	LYS	A	205	 205 	VAL	B	Protein	S	2
FT	#SUB	22	  22 	ARG	A	173	 173 	ASN	B	Protein	S	3
FT	#SUB	29	  29 	SER	A	204	 204 	TYR	B	Protein	S	3
FT	#SUB	31	  31 	PHE	A	36	  36 	ARG	B	Protein	B	4
FT	#SUB	31	  31 	PHE	A	202	 202 	GLN	B	Protein	S	1
FT	#SUB	31	  31 	PHE	A	204	 204 	TYR	B	Protein	S	13
FT	#SUB	31	  31 	PHE	A	211	 211 	SER	B	Protein	S	1
FT	#SUB	31	  31 	PHE	A	212	 212 	CYS	B	Protein	S	3
FT	#SUB	31	  31 	PHE	A	213	 213 	GLN	B	Protein	S	4
FT	#SUB	31	  31 	PHE	A	251	 251 	VAL	B	Protein	B	1
FT	#SUB	32	  32 	GLY	A	34	  34 	GLN	B	Protein	B	3
FT	#SUB	32	  32 	GLY	A	36	  36 	ARG	B	Protein	B	3
FT	#SUB	32	  32 	GLY	A	213	 213 	GLN	B	Protein	B	1
FT	#SUB	33	  33 	TYR	A	34	  34 	GLN	B	Protein	B	9
FT	#SUB	34	  34 	GLN	A	32	  32 	GLY	B	Protein	S	2
FT	#SUB	34	  34 	GLN	A	33	  33 	TYR	B	Protein	S	12
FT	#SUB	34	  34 	GLN	A	34	  34 	GLN	B	Protein	A	8
FT	#SUB	34	  34 	GLN	A	253	 253 	THR	B	Protein	S	1
FT	#SUB	36	  36 	ARG	A	31	  31 	PHE	B	Protein	S	3
FT	#SUB	36	  36 	ARG	A	32	  32 	GLY	B	Protein	S	4
FT	#SUB	152	 152 	TRP	A	186	 186 	PRO	B	Protein	S	5
FT	#SUB	153	 153 	GLU	A	155	 155 	LYS	B	Protein	A	5
FT	#SUB	154	 154 	THR	A	155	 155 	LYS	B	Protein	B	2
FT	#SUB	154	 154 	THR	A	187	 187 	GLU	B	Protein	A	10
FT	#SUB	155	 155 	LYS	A	154	 154 	THR	B	Protein	S	3
FT	#SUB	155	 155 	LYS	A	155	 155 	LYS	B	Protein	A	2
FT	#SUB	155	 155 	LYS	A	187	 187 	GLU	B	Protein	A	11
FT	#SUB	160	 160 	ILE	A	186	 186 	PRO	B	Protein	S	3
FT	#SUB	160	 160 	ILE	A	187	 187 	GLU	B	Protein	S	2
FT	#SUB	162	 162 	GLN	A	186	 186 	PRO	B	Protein	S	2
FT	#SUB	175	 175 	ASP	A	19	  19 	LYS	B	Protein	A	7
FT	#SUB	175	 175 	ASP	A	20	  20 	GLU	B	Protein	S	7
FT	#SUB	177	 177 	ARG	A	21	  21 	ASP	B	Protein	S	8
FT	#SUB	177	 177 	ARG	A	27	  27 	THR	B	Protein	S	1
FT	#SUB	177	 177 	ARG	A	217	 217 	ARG	B	Protein	A	5
FT	#SUB	177	 177 	ARG	A	218	 218 	SER	B	Protein	S	2
FT	#SUB	177	 177 	ARG	A	256	 256 	ASP	B	Protein	S	4
FT	#SUB	177	 177 	ARG	A	258	 258 	HIS	B	Protein	S	5
FT	#SUB	177	 177 	ARG	A	260	 260 	TYR	B	Protein	S	3
FT	#SUB	178	 178 	ARG	A	22	  22 	ARG	B	Protein	S	5
FT	#SUB	178	 178 	ARG	A	194	 194 	LEU	B	Protein	S	1
FT	#SUB	178	 178 	ARG	A	195	 195 	PRO	B	Protein	S	7
FT	#SUB	178	 178 	ARG	A	217	 217 	ARG	B	Protein	S	2
FT	#SUB	180	 180 	ILE	A	184	 184 	TRP	B	Protein	S	7
FT	#SUB	182	 182 	SER	A	184	 184 	TRP	B	Protein	S	1
FT	#SUB	184	 184 	TRP	A	180	 180 	ILE	B	Protein	S	5
FT	#SUB	184	 184 	TRP	A	182	 182 	SER	B	Protein	S	1
FT	#SUB	184	 184 	TRP	A	200	 200 	MET	B	Protein	S	2
FT	#SUB	185	 185 	ASN	A	152	 152 	TRP	B	Protein	S	3
FT	#SUB	185	 185 	ASN	A	155	 155 	LYS	B	Protein	S	1
FT	#SUB	186	 186 	PRO	A	152	 152 	TRP	B	Protein	S	12
FT	#SUB	186	 186 	PRO	A	162	 162 	GLN	B	Protein	S	2
FT	#SUB	187	 187 	GLU	A	154	 154 	THR	B	Protein	S	3
FT	#SUB	187	 187 	GLU	A	155	 155 	LYS	B	Protein	S	9
FT	#SUB	187	 187 	GLU	A	156	 156 	ASP	B	Protein	S	1
FT	#SUB	195	 195 	PRO	A	178	 178 	ARG	B	Protein	S	4
FT	#SUB	199	 199 	THR	A	200	 200 	MET	B	Protein	S	3
FT	#SUB	200	 200 	MET	A	184	 184 	TRP	B	Protein	S	1
FT	#SUB	200	 200 	MET	A	199	 199 	THR	B	Protein	S	2
FT	#SUB	200	 200 	MET	A	200	 200 	MET	B	Protein	S	4
FT	#SUB	202	 202 	GLN	A	31	  31 	PHE	B	Protein	A	3
FT	#SUB	202	 202 	GLN	A	215	 215 	TYR	B	Protein	S	3
FT	#SUB	202	 202 	GLN	A	217	 217 	ARG	B	Protein	S	10
FT	#SUB	202	 202 	GLN	A	255	 255 	GLY	B	Protein	S	1
FT	#SUB	204	 204 	TYR	A	17	  17 	HIS	B	Protein	S	1
FT	#SUB	204	 204 	TYR	A	19	  19 	LYS	B	Protein	S	6
FT	#SUB	204	 204 	TYR	A	29	  29 	SER	B	Protein	S	5
FT	#SUB	204	 204 	TYR	A	31	  31 	PHE	B	Protein	S	12
FT	#SUB	204	 204 	TYR	A	256	 256 	ASP	B	Protein	S	1
FT	#SUB	205	 205 	VAL	A	19	  19 	LYS	B	Protein	B	2
FT	#SUB	206	 206 	ASN	A	17	  17 	HIS	B	Protein	S	4
FT	#SUB	206	 206 	ASN	A	18	  18 	PHE	B	Protein	S	1
FT	#SUB	211	 211 	SER	A	31	  31 	PHE	B	Protein	S	1
FT	#SUB	212	 212 	CYS	A	31	  31 	PHE	B	Protein	B	1
FT	#SUB	213	 213 	GLN	A	31	  31 	PHE	B	Protein	A	4
FT	#SUB	213	 213 	GLN	A	215	 215 	TYR	B	Protein	S	8
FT	#SUB	213	 213 	GLN	A	253	 253 	THR	B	Protein	S	1
FT	#SUB	213	 213 	GLN	A	254	 254 	LEU	B	Protein	S	3
FT	#SUB	213	 213 	GLN	A	255	 255 	GLY	B	Protein	S	2
FT	#SUB	215	 215 	TYR	A	202	 202 	GLN	B	Protein	S	5
FT	#SUB	215	 215 	TYR	A	213	 213 	GLN	B	Protein	S	6
FT	#SUB	217	 217 	ARG	A	177	 177 	ARG	B	Protein	S	5
FT	#SUB	217	 217 	ARG	A	178	 178 	ARG	B	Protein	S	1
FT	#SUB	217	 217 	ARG	A	180	 180 	ILE	B	Protein	S	2
FT	#SUB	217	 217 	ARG	A	202	 202 	GLN	B	Protein	A	9
FT	#SUB	218	 218 	SER	A	177	 177 	ARG	B	Protein	S	3
FT	#SUB	253	 253 	THR	A	34	  34 	GLN	B	Protein	S	1
FT	#SUB	253	 253 	THR	A	213	 213 	GLN	B	Protein	S	1
FT	#SUB	253	 253 	THR	A	253	 253 	THR	B	Protein	S	3
FT	#SUB	254	 254 	LEU	A	213	 213 	GLN	B	Protein	B	4
FT	#SUB	255	 255 	GLY	A	202	 202 	GLN	B	Protein	B	1
FT	#SUB	255	 255 	GLY	A	213	 213 	GLN	B	Protein	B	2
FT	#SUB	256	 256 	ASP	A	177	 177 	ARG	B	Protein	S	4
FT	#SUB	256	 256 	ASP	A	204	 204 	TYR	B	Protein	S	4
FT	#SUB	258	 258 	HIS	A	177	 177 	ARG	B	Protein	S	9
FT	#SUB	260	 260 	TYR	A	177	 177 	ARG	B	Protein	S	1
FT	#SUB	21	  21 	ASP	A	88	  88 	ARG	C	Protein	B	1
FT	#SUB	22	  22 	ARG	A	88	  88 	ARG	C	Protein	B	2
FT	#SUB	22	  22 	ARG	A	190	 190 	PRO	C	Protein	S	1
FT	#SUB	22	  22 	ARG	A	191	 191 	SER	C	Protein	S	3
FT	#SUB	23	  23 	THR	A	91	  91 	LYS	C	Protein	B	2
FT	#SUB	24	  24 	GLY	A	88	  88 	ARG	C	Protein	B	1
FT	#SUB	24	  24 	GLY	A	91	  91 	LYS	C	Protein	B	2
FT	#SUB	25	  25 	THR	A	91	  91 	LYS	C	Protein	S	2
FT	#SUB	87	  87 	GLU	A	23	  23 	THR	C	Protein	S	1
FT	#SUB	88	  88 	ARG	A	23	  23 	THR	C	Protein	B	1
FT	#SUB	91	  91 	LYS	A	23	  23 	THR	C	Protein	S	3
FT	#SUB	91	  91 	LYS	A	24	  24 	GLY	C	Protein	S	2
FT	#SUB	91	  91 	LYS	A	25	  25 	THR	C	Protein	S	2
FT	#SUB	91	  91 	LYS	A	261	 261 	GLN	C	Protein	B	1
FT	#SUB	91	  91 	LYS	A	262	 262 	ASN	C	Protein	B	2
FT	#SUB	190	 190 	PRO	A	22	  22 	ARG	C	Protein	B	1
FT	#SUB	191	 191 	SER	A	22	  22 	ARG	C	Protein	B	2
FT	#SUB	261	 261 	GLN	A	91	  91 	LYS	C	Protein	S	1
FT	#SUB	186	 186 	PRO	A	172	 172 	THR	D	Protein	B	1
FT	#SUB	187	 187 	GLU	A	172	 172 	THR	D	Protein	B	1
FT	#SUB	190	 190 	PRO	A	172	 172 	THR	D	Protein	S	5
FT	#SUB	191	 191 	SER	A	172	 172 	THR	D	Protein	S	1
FT	#HET	177	 177 	ARG	A	1	401 	UFP	B	S	10
FT	#HET	178	 178 	ARG	A	1	401 	UFP	B	S	6
FT	#HET	217	 217 	ARG	A	2	402 	SO4	B	S	5
FT	#HET	218	 218 	SER	A	2	402 	SO4	B	S	2
FT	DISORDER	98	118
FT	DISORDER	314	315
CC	SEQUENCE	292 AA (ATOM);
CC	MEEAYLALGK KILEEGHFKE DRTGTGTYSL FGYQMRFDLA KGFPLLTTKR VPFGLIKSEL
CC	LWFLKGDTNI RYLLERNNHI WDEWAFERYV KSADYQGEEH QKFCDAILND AEFAEKYGEL
CC	GNIYGAQWRH WETKDGSFID QLANVIEMIK TNPDSRRLIV SAWNPEDVPS MALPPXHTMF
CC	QFYVNEGKLS CQLYQRSADV FLGVPFNIAS YALLTHLIAH ETGLEVGEFV HTLGDAHLYQ
CC	NHVEQMQEQL SREVRSFPTL VLNPDKASVF DFDMEDIKVE GYDPHPTIKA PI
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MEEAYLALGKKILEEGHFKEDRTGTGTYSLFGYQMRFDLAKGFPLLTTKR
CC	ATOM   MEEAYLALGKKILEEGHFKEDRTGTGTYSLFGYQMRFDLAKGFPLLTTKR
CC	       **************************************************
CC	SEQRES VPFGLIKSELLWFLKGDTNIRYLLERNNHIWDEWAFERYVKSADYQGPDM
CC	ATOM   VPFGLIKSELLWFLKGDTNIRYLLERNNHIWDEWAFERYVKSADYQG---
CC	       ***********************************************   
CC	SEQRES TDFGHRVLQDPAFAEQYKEEHQKFCDAILNDAEFAEKYGELGNIYGAQWR
CC	ATOM   ------------------EEHQKFCDAILNDAEFAEKYGELGNIYGAQWR
CC	                         ********************************
CC	SEQRES HWETKDGSFIDQLANVIEMIKTNPDSRRLIVSAWNPEDVPSMALPPXHTM
CC	ATOM   HWETKDGSFIDQLANVIEMIKTNPDSRRLIVSAWNPEDVPSMALPPXHTM
CC	       **************************************************
CC	SEQRES FQFYVNEGKLSCQLYQRSADVFLGVPFNIASYALLTHLIAHETGLEVGEF
CC	ATOM   FQFYVNEGKLSCQLYQRSADVFLGVPFNIASYALLTHLIAHETGLEVGEF
CC	       **************************************************
CC	SEQRES VHTLGDAHLYQNHVEQMQEQLSREVRSFPTLVLNPDKASVFDFDMEDIKV
CC	ATOM   VHTLGDAHLYQNHVEQMQEQLSREVRSFPTLVLNPDKASVFDFDMEDIKV
CC	       **************************************************
CC	SEQRES EGYDPHPTIKAPIAV
CC	ATOM   EGYDPHPTIKAPI--
CC	       *************  
SQ	SEQUENCE	315 AA;      MW;         CN;
	MEEAYLALGK KILEEGHFKE DRTGTGTYSL FGYQMRFDLA KGFPLLTTKR VPFGLIKSEL
	LWFLKGDTNI RYLLERNNHI WDEWAFERYV KSADYQGPDM TDFGHRVLQD PAFAEQYKEE
	HQKFCDAILN DAEFAEKYGE LGNIYGAQWR HWETKDGSFI DQLANVIEMI KTNPDSRRLI
	VSAWNPEDVP SMALPPXHTM FQFYVNEGKL SCQLYQRSAD VFLGVPFNIA SYALLTHLIA
	HETGLEVGEF VHTLGDAHLY QNHVEQMQEQ LSREVRSFPT LVLNPDKASV FDFDMEDIKV
	EGYDPHPTIK APIAV
//
ID	6QXSB	STANDARD;	PRT;	315	AA.
DT	CONVERTED FROM PDB (SEQRES) 6QXS
DE	Thymidylate synthase
OS	Enterococcus faecalis
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.880
CC	R-Factor	0.203
FT	#SUB	17	  17 	HIS	B	204	 204 	TYR	A	Protein	S	1
FT	#SUB	17	  17 	HIS	B	206	 206 	ASN	A	Protein	S	4
FT	#SUB	18	  18 	PHE	B	206	 206 	ASN	A	Protein	B	1
FT	#SUB	19	  19 	LYS	B	175	 175 	ASP	A	Protein	S	7
FT	#SUB	19	  19 	LYS	B	204	 204 	TYR	A	Protein	S	6
FT	#SUB	19	  19 	LYS	B	205	 205 	VAL	A	Protein	S	2
FT	#SUB	20	  20 	GLU	B	175	 175 	ASP	A	Protein	A	7
FT	#SUB	21	  21 	ASP	B	177	 177 	ARG	A	Protein	S	8
FT	#SUB	22	  22 	ARG	B	178	 178 	ARG	A	Protein	S	5
FT	#SUB	27	  27 	THR	B	177	 177 	ARG	A	Protein	S	1
FT	#SUB	29	  29 	SER	B	204	 204 	TYR	A	Protein	A	5
FT	#SUB	31	  31 	PHE	B	36	  36 	ARG	A	Protein	B	3
FT	#SUB	31	  31 	PHE	B	202	 202 	GLN	A	Protein	S	3
FT	#SUB	31	  31 	PHE	B	204	 204 	TYR	A	Protein	S	12
FT	#SUB	31	  31 	PHE	B	211	 211 	SER	A	Protein	S	1
FT	#SUB	31	  31 	PHE	B	212	 212 	CYS	A	Protein	S	1
FT	#SUB	31	  31 	PHE	B	213	 213 	GLN	A	Protein	S	4
FT	#SUB	32	  32 	GLY	B	34	  34 	GLN	A	Protein	B	2
FT	#SUB	32	  32 	GLY	B	36	  36 	ARG	A	Protein	B	4
FT	#SUB	33	  33 	TYR	B	34	  34 	GLN	A	Protein	B	12
FT	#SUB	34	  34 	GLN	B	32	  32 	GLY	A	Protein	S	3
FT	#SUB	34	  34 	GLN	B	33	  33 	TYR	A	Protein	S	9
FT	#SUB	34	  34 	GLN	B	34	  34 	GLN	A	Protein	A	8
FT	#SUB	34	  34 	GLN	B	253	 253 	THR	A	Protein	S	1
FT	#SUB	36	  36 	ARG	B	31	  31 	PHE	A	Protein	S	4
FT	#SUB	36	  36 	ARG	B	32	  32 	GLY	A	Protein	S	3
FT	#SUB	152	 152 	TRP	B	185	 185 	ASN	A	Protein	S	3
FT	#SUB	152	 152 	TRP	B	186	 186 	PRO	A	Protein	S	12
FT	#SUB	154	 154 	THR	B	155	 155 	LYS	A	Protein	B	3
FT	#SUB	154	 154 	THR	B	187	 187 	GLU	A	Protein	A	3
FT	#SUB	155	 155 	LYS	B	153	 153 	GLU	A	Protein	S	5
FT	#SUB	155	 155 	LYS	B	154	 154 	THR	A	Protein	S	2
FT	#SUB	155	 155 	LYS	B	155	 155 	LYS	A	Protein	B	2
FT	#SUB	155	 155 	LYS	B	185	 185 	ASN	A	Protein	S	1
FT	#SUB	155	 155 	LYS	B	187	 187 	GLU	A	Protein	A	9
FT	#SUB	156	 156 	ASP	B	187	 187 	GLU	A	Protein	S	1
FT	#SUB	162	 162 	GLN	B	186	 186 	PRO	A	Protein	S	2
FT	#SUB	173	 173 	ASN	B	22	  22 	ARG	A	Protein	S	3
FT	#SUB	175	 175 	ASP	B	19	  19 	LYS	A	Protein	S	3
FT	#SUB	177	 177 	ARG	B	217	 217 	ARG	A	Protein	A	5
FT	#SUB	177	 177 	ARG	B	218	 218 	SER	A	Protein	S	3
FT	#SUB	177	 177 	ARG	B	256	 256 	ASP	A	Protein	S	4
FT	#SUB	177	 177 	ARG	B	258	 258 	HIS	A	Protein	S	9
FT	#SUB	177	 177 	ARG	B	260	 260 	TYR	A	Protein	S	1
FT	#SUB	178	 178 	ARG	B	195	 195 	PRO	A	Protein	S	4
FT	#SUB	178	 178 	ARG	B	217	 217 	ARG	A	Protein	S	1
FT	#SUB	180	 180 	ILE	B	184	 184 	TRP	A	Protein	S	5
FT	#SUB	180	 180 	ILE	B	217	 217 	ARG	A	Protein	S	2
FT	#SUB	182	 182 	SER	B	184	 184 	TRP	A	Protein	S	1
FT	#SUB	184	 184 	TRP	B	180	 180 	ILE	A	Protein	S	7
FT	#SUB	184	 184 	TRP	B	182	 182 	SER	A	Protein	S	1
FT	#SUB	184	 184 	TRP	B	200	 200 	MET	A	Protein	S	1
FT	#SUB	186	 186 	PRO	B	152	 152 	TRP	A	Protein	S	5
FT	#SUB	186	 186 	PRO	B	160	 160 	ILE	A	Protein	A	3
FT	#SUB	186	 186 	PRO	B	162	 162 	GLN	A	Protein	S	2
FT	#SUB	187	 187 	GLU	B	154	 154 	THR	A	Protein	S	10
FT	#SUB	187	 187 	GLU	B	155	 155 	LYS	A	Protein	S	11
FT	#SUB	187	 187 	GLU	B	160	 160 	ILE	A	Protein	B	2
FT	#SUB	194	 194 	LEU	B	178	 178 	ARG	A	Protein	S	1
FT	#SUB	195	 195 	PRO	B	178	 178 	ARG	A	Protein	S	7
FT	#SUB	199	 199 	THR	B	200	 200 	MET	A	Protein	S	2
FT	#SUB	200	 200 	MET	B	184	 184 	TRP	A	Protein	S	2
FT	#SUB	200	 200 	MET	B	199	 199 	THR	A	Protein	S	3
FT	#SUB	200	 200 	MET	B	200	 200 	MET	A	Protein	S	4
FT	#SUB	202	 202 	GLN	B	31	  31 	PHE	A	Protein	B	1
FT	#SUB	202	 202 	GLN	B	215	 215 	TYR	A	Protein	S	5
FT	#SUB	202	 202 	GLN	B	217	 217 	ARG	A	Protein	S	9
FT	#SUB	202	 202 	GLN	B	255	 255 	GLY	A	Protein	S	1
FT	#SUB	204	 204 	TYR	B	17	  17 	HIS	A	Protein	S	1
FT	#SUB	204	 204 	TYR	B	19	  19 	LYS	A	Protein	S	4
FT	#SUB	204	 204 	TYR	B	29	  29 	SER	A	Protein	S	3
FT	#SUB	204	 204 	TYR	B	31	  31 	PHE	A	Protein	S	13
FT	#SUB	204	 204 	TYR	B	256	 256 	ASP	A	Protein	S	4
FT	#SUB	205	 205 	VAL	B	19	  19 	LYS	A	Protein	B	2
FT	#SUB	206	 206 	ASN	B	17	  17 	HIS	A	Protein	S	11
FT	#SUB	211	 211 	SER	B	31	  31 	PHE	A	Protein	B	1
FT	#SUB	212	 212 	CYS	B	31	  31 	PHE	A	Protein	B	3
FT	#SUB	213	 213 	GLN	B	31	  31 	PHE	A	Protein	A	4
FT	#SUB	213	 213 	GLN	B	32	  32 	GLY	A	Protein	S	1
FT	#SUB	213	 213 	GLN	B	215	 215 	TYR	A	Protein	S	6
FT	#SUB	213	 213 	GLN	B	253	 253 	THR	A	Protein	S	1
FT	#SUB	213	 213 	GLN	B	254	 254 	LEU	A	Protein	S	4
FT	#SUB	213	 213 	GLN	B	255	 255 	GLY	A	Protein	S	2
FT	#SUB	215	 215 	TYR	B	202	 202 	GLN	A	Protein	S	3
FT	#SUB	215	 215 	TYR	B	213	 213 	GLN	A	Protein	S	8
FT	#SUB	217	 217 	ARG	B	177	 177 	ARG	A	Protein	S	5
FT	#SUB	217	 217 	ARG	B	178	 178 	ARG	A	Protein	S	2
FT	#SUB	217	 217 	ARG	B	202	 202 	GLN	A	Protein	A	10
FT	#SUB	218	 218 	SER	B	177	 177 	ARG	A	Protein	S	2
FT	#SUB	251	 251 	VAL	B	31	  31 	PHE	A	Protein	S	1
FT	#SUB	253	 253 	THR	B	34	  34 	GLN	A	Protein	S	1
FT	#SUB	253	 253 	THR	B	213	 213 	GLN	A	Protein	S	1
FT	#SUB	253	 253 	THR	B	253	 253 	THR	A	Protein	S	3
FT	#SUB	254	 254 	LEU	B	213	 213 	GLN	A	Protein	B	3
FT	#SUB	255	 255 	GLY	B	202	 202 	GLN	A	Protein	B	1
FT	#SUB	255	 255 	GLY	B	213	 213 	GLN	A	Protein	B	2
FT	#SUB	256	 256 	ASP	B	177	 177 	ARG	A	Protein	S	4
FT	#SUB	256	 256 	ASP	B	204	 204 	TYR	A	Protein	S	1
FT	#SUB	258	 258 	HIS	B	177	 177 	ARG	A	Protein	S	5
FT	#SUB	260	 260 	TYR	B	177	 177 	ARG	A	Protein	S	3
FT	#SUB	172	 172 	THR	B	186	 186 	PRO	C	Protein	S	1
FT	#SUB	172	 172 	THR	B	187	 187 	GLU	C	Protein	S	1
FT	#SUB	172	 172 	THR	B	190	 190 	PRO	C	Protein	S	5
FT	#SUB	172	 172 	THR	B	191	 191 	SER	C	Protein	B	2
FT	#SUB	173	 173 	ASN	B	191	 191 	SER	C	Protein	S	2
FT	#SUB	151	 151 	HIS	B	288	 288 	ALA	D	Protein	S	1
FT	#SUB	157	 157 	GLY	B	244	 244 	GLY	D	Protein	B	1
FT	#SUB	158	 158 	SER	B	171	 171 	LYS	D	Protein	S	1
FT	#SUB	158	 158 	SER	B	242	 242 	GLU	D	Protein	S	3
FT	#SUB	158	 158 	SER	B	243	 243 	THR	D	Protein	S	4
FT	#SUB	159	 159 	PHE	B	171	 171 	LYS	D	Protein	A	6
FT	#SUB	159	 159 	PHE	B	242	 242 	GLU	D	Protein	S	2
FT	#SUB	159	 159 	PHE	B	288	 288 	ALA	D	Protein	S	1
FT	#SUB	160	 160 	ILE	B	168	 168 	GLU	D	Protein	B	2
FT	#SUB	160	 160 	ILE	B	172	 172 	THR	D	Protein	S	1
FT	#SUB	161	 161 	ASP	B	168	 168 	GLU	D	Protein	A	6
FT	#SUB	165	 165 	ASN	B	168	 168 	GLU	D	Protein	S	7
FT	#SUB	168	 168 	GLU	B	160	 160 	ILE	D	Protein	S	3
FT	#SUB	168	 168 	GLU	B	161	 161 	ASP	D	Protein	S	7
FT	#SUB	168	 168 	GLU	B	165	 165 	ASN	D	Protein	S	6
FT	#SUB	171	 171 	LYS	B	158	 158 	SER	D	Protein	S	3
FT	#SUB	171	 171 	LYS	B	159	 159 	PHE	D	Protein	S	9
FT	#SUB	172	 172 	THR	B	160	 160 	ILE	D	Protein	S	1
FT	#SUB	242	 242 	GLU	B	158	 158 	SER	D	Protein	B	2
FT	#SUB	242	 242 	GLU	B	159	 159 	PHE	D	Protein	S	6
FT	#SUB	243	 243 	THR	B	158	 158 	SER	D	Protein	B	3
FT	#SUB	288	 288 	ALA	B	159	 159 	PHE	D	Protein	B	1
FT	#HET	22	  22 	ARG	B	1	401 	UFP	B	S	9
FT	#HET	52	  52 	PRO	B	3	403 	FFO	B	S	1
FT	#HET	55	  55 	LEU	B	3	403 	FFO	B	S	1
FT	#HET	80	  80 	ILE	B	3	403 	FFO	B	A	6
FT	#HET	81	  81 	TRP	B	3	403 	FFO	B	S	4
FT	#HET	84	  84 	TRP	B	3	403 	FFO	B	S	6
FT	#HET	145	 145 	TYR	B	1	401 	UFP	B	S	6
FT	#HET	177	 177 	ARG	B	2	402 	SO4	B	S	7
FT	#HET	178	 178 	ARG	B	2	402 	SO4	B	S	3
FT	#HET	194	 194 	LEU	B	1	401 	UFP	B	S	1
FT	#HET	194	 194 	LEU	B	3	403 	FFO	B	S	1
FT	#HET	197	 197 	CYS	B	1	401 	UFP	B	S	15
FT	#HET	198	 198 	HIS	B	1	401 	UFP	B	S	6
FT	#HET	216	 216 	GLN	B	1	401 	UFP	B	S	3
FT	#HET	217	 217 	ARG	B	1	401 	UFP	B	S	7
FT	#HET	218	 218 	SER	B	1	401 	UFP	B	A	8
FT	#HET	219	 219 	ALA	B	1	401 	UFP	B	B	1
FT	#HET	220	 220 	ASP	B	1	401 	UFP	B	A	5
FT	#HET	220	 220 	ASP	B	3	403 	FFO	B	S	8
FT	#HET	223	 223 	LEU	B	3	403 	FFO	B	A	3
FT	#HET	224	 224 	GLY	B	1	401 	UFP	B	B	1
FT	#HET	224	 224 	GLY	B	3	403 	FFO	B	B	2
FT	#HET	227	 227 	PHE	B	3	403 	FFO	B	S	9
FT	#HET	228	 228 	ASN	B	1	401 	UFP	B	S	6
FT	#HET	228	 228 	ASN	B	3	403 	FFO	B	S	1
FT	#HET	258	 258 	HIS	B	1	401 	UFP	B	S	5
FT	#HET	260	 260 	TYR	B	1	401 	UFP	B	S	5
FT	#HET	260	 260 	TYR	B	3	403 	FFO	B	S	3
FT	#HET	313	 313 	ILE	B	3	403 	FFO	B	S	4
FT	#HET	314	 314 	ALA	B	3	403 	FFO	B	B	1
CC	SEQUENCE	315 AA (ATOM);
CC	MEEAYLALGK KILEEGHFKE DRTGTGTYSL FGYQMRFDLA KGFPLLTTKR VPFGLIKSEL
CC	LWFLKGDTNI RYLLERNNHI WDEWAFERYV KSADYQGPDM TDFGHRVLQD PAFAEQYKEE
CC	HQKFCDAILN DAEFAEKYGE LGNIYGAQWR HWETKDGSFI DQLANVIEMI KTNPDSRRLI
CC	VSAWNPEDVP SMALPPCHTM FQFYVNEGKL SCQLYQRSAD VFLGVPFNIA SYALLTHLIA
CC	HETGLEVGEF VHTLGDAHLY QNHVEQMQEQ LSREVRSFPT LVLNPDKASV FDFDMEDIKV
CC	EGYDPHPTIK APIAV
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MEEAYLALGKKILEEGHFKEDRTGTGTYSLFGYQMRFDLAKGFPLLTTKR
CC	ATOM   MEEAYLALGKKILEEGHFKEDRTGTGTYSLFGYQMRFDLAKGFPLLTTKR
CC	       **************************************************
CC	SEQRES VPFGLIKSELLWFLKGDTNIRYLLERNNHIWDEWAFERYVKSADYQGPDM
CC	ATOM   VPFGLIKSELLWFLKGDTNIRYLLERNNHIWDEWAFERYVKSADYQGPDM
CC	       **************************************************
CC	SEQRES TDFGHRVLQDPAFAEQYKEEHQKFCDAILNDAEFAEKYGELGNIYGAQWR
CC	ATOM   TDFGHRVLQDPAFAEQYKEEHQKFCDAILNDAEFAEKYGELGNIYGAQWR
CC	       **************************************************
CC	SEQRES HWETKDGSFIDQLANVIEMIKTNPDSRRLIVSAWNPEDVPSMALPPCHTM
CC	ATOM   HWETKDGSFIDQLANVIEMIKTNPDSRRLIVSAWNPEDVPSMALPPCHTM
CC	       **************************************************
CC	SEQRES FQFYVNEGKLSCQLYQRSADVFLGVPFNIASYALLTHLIAHETGLEVGEF
CC	ATOM   FQFYVNEGKLSCQLYQRSADVFLGVPFNIASYALLTHLIAHETGLEVGEF
CC	       **************************************************
CC	SEQRES VHTLGDAHLYQNHVEQMQEQLSREVRSFPTLVLNPDKASVFDFDMEDIKV
CC	ATOM   VHTLGDAHLYQNHVEQMQEQLSREVRSFPTLVLNPDKASVFDFDMEDIKV
CC	       **************************************************
CC	SEQRES EGYDPHPTIKAPIAV
CC	ATOM   EGYDPHPTIKAPIAV
CC	       ***************
SQ	SEQUENCE	315 AA;      MW;         CN;
	MEEAYLALGK KILEEGHFKE DRTGTGTYSL FGYQMRFDLA KGFPLLTTKR VPFGLIKSEL
	LWFLKGDTNI RYLLERNNHI WDEWAFERYV KSADYQGPDM TDFGHRVLQD PAFAEQYKEE
	HQKFCDAILN DAEFAEKYGE LGNIYGAQWR HWETKDGSFI DQLANVIEMI KTNPDSRRLI
	VSAWNPEDVP SMALPPCHTM FQFYVNEGKL SCQLYQRSAD VFLGVPFNIA SYALLTHLIA
	HETGLEVGEF VHTLGDAHLY QNHVEQMQEQ LSREVRSFPT LVLNPDKASV FDFDMEDIKV
	EGYDPHPTIK APIAV
//
ID	6QXSC	STANDARD;	PRT;	315	AA.
DT	CONVERTED FROM PDB (SEQRES) 6QXS
DE	Thymidylate synthase
OS	Enterococcus faecalis
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.880
CC	R-Factor	0.203
FT	#SUB	22	  22 	ARG	C	190	 190 	PRO	A	Protein	S	1
FT	#SUB	22	  22 	ARG	C	191	 191 	SER	A	Protein	S	2
FT	#SUB	23	  23 	THR	C	87	  87 	GLU	A	Protein	B	1
FT	#SUB	23	  23 	THR	C	88	  88 	ARG	A	Protein	B	1
FT	#SUB	23	  23 	THR	C	91	  91 	LYS	A	Protein	A	3
FT	#SUB	24	  24 	GLY	C	91	  91 	LYS	A	Protein	B	2
FT	#SUB	25	  25 	THR	C	91	  91 	LYS	A	Protein	S	2
FT	#SUB	88	  88 	ARG	C	21	  21 	ASP	A	Protein	S	1
FT	#SUB	88	  88 	ARG	C	22	  22 	ARG	A	Protein	S	2
FT	#SUB	88	  88 	ARG	C	24	  24 	GLY	A	Protein	S	1
FT	#SUB	91	  91 	LYS	C	23	  23 	THR	A	Protein	S	2
FT	#SUB	91	  91 	LYS	C	24	  24 	GLY	A	Protein	A	2
FT	#SUB	91	  91 	LYS	C	25	  25 	THR	A	Protein	S	2
FT	#SUB	91	  91 	LYS	C	261	 261 	GLN	A	Protein	B	1
FT	#SUB	190	 190 	PRO	C	22	  22 	ARG	A	Protein	B	1
FT	#SUB	191	 191 	SER	C	22	  22 	ARG	A	Protein	B	3
FT	#SUB	261	 261 	GLN	C	91	  91 	LYS	A	Protein	S	1
FT	#SUB	262	 262 	ASN	C	91	  91 	LYS	A	Protein	S	2
FT	#SUB	186	 186 	PRO	C	172	 172 	THR	B	Protein	B	1
FT	#SUB	187	 187 	GLU	C	172	 172 	THR	B	Protein	B	1
FT	#SUB	190	 190 	PRO	C	172	 172 	THR	B	Protein	S	5
FT	#SUB	191	 191 	SER	C	172	 172 	THR	B	Protein	S	2
FT	#SUB	191	 191 	SER	C	173	 173 	ASN	B	Protein	A	2
FT	#SUB	17	  17 	HIS	C	204	 204 	TYR	D	Protein	S	2
FT	#SUB	17	  17 	HIS	C	206	 206 	ASN	D	Protein	S	12
FT	#SUB	19	  19 	LYS	C	175	 175 	ASP	D	Protein	S	4
FT	#SUB	19	  19 	LYS	C	204	 204 	TYR	D	Protein	S	4
FT	#SUB	19	  19 	LYS	C	205	 205 	VAL	D	Protein	S	3
FT	#SUB	19	  19 	LYS	C	206	 206 	ASN	D	Protein	S	1
FT	#SUB	22	  22 	ARG	C	173	 173 	ASN	D	Protein	S	1
FT	#SUB	29	  29 	SER	C	204	 204 	TYR	D	Protein	A	4
FT	#SUB	31	  31 	PHE	C	36	  36 	ARG	D	Protein	B	4
FT	#SUB	31	  31 	PHE	C	202	 202 	GLN	D	Protein	S	1
FT	#SUB	31	  31 	PHE	C	204	 204 	TYR	D	Protein	S	13
FT	#SUB	31	  31 	PHE	C	212	 212 	CYS	D	Protein	S	2
FT	#SUB	31	  31 	PHE	C	213	 213 	GLN	D	Protein	S	4
FT	#SUB	32	  32 	GLY	C	34	  34 	GLN	D	Protein	B	1
FT	#SUB	32	  32 	GLY	C	36	  36 	ARG	D	Protein	B	3
FT	#SUB	32	  32 	GLY	C	213	 213 	GLN	D	Protein	B	1
FT	#SUB	33	  33 	TYR	C	34	  34 	GLN	D	Protein	B	8
FT	#SUB	34	  34 	GLN	C	32	  32 	GLY	D	Protein	S	3
FT	#SUB	34	  34 	GLN	C	33	  33 	TYR	D	Protein	S	11
FT	#SUB	34	  34 	GLN	C	34	  34 	GLN	D	Protein	A	5
FT	#SUB	34	  34 	GLN	C	253	 253 	THR	D	Protein	S	1
FT	#SUB	36	  36 	ARG	C	31	  31 	PHE	D	Protein	S	3
FT	#SUB	36	  36 	ARG	C	32	  32 	GLY	D	Protein	S	4
FT	#SUB	152	 152 	TRP	C	186	 186 	PRO	D	Protein	S	5
FT	#SUB	154	 154 	THR	C	155	 155 	LYS	D	Protein	B	1
FT	#SUB	154	 154 	THR	C	187	 187 	GLU	D	Protein	A	9
FT	#SUB	155	 155 	LYS	C	153	 153 	GLU	D	Protein	S	1
FT	#SUB	155	 155 	LYS	C	154	 154 	THR	D	Protein	S	2
FT	#SUB	155	 155 	LYS	C	187	 187 	GLU	D	Protein	A	10
FT	#SUB	160	 160 	ILE	C	186	 186 	PRO	D	Protein	S	2
FT	#SUB	162	 162 	GLN	C	184	 184 	TRP	D	Protein	S	1
FT	#SUB	162	 162 	GLN	C	186	 186 	PRO	D	Protein	S	2
FT	#SUB	175	 175 	ASP	C	19	  19 	LYS	D	Protein	S	3
FT	#SUB	175	 175 	ASP	C	20	  20 	GLU	D	Protein	S	5
FT	#SUB	177	 177 	ARG	C	21	  21 	ASP	D	Protein	S	3
FT	#SUB	177	 177 	ARG	C	217	 217 	ARG	D	Protein	A	5
FT	#SUB	177	 177 	ARG	C	218	 218 	SER	D	Protein	S	2
FT	#SUB	177	 177 	ARG	C	256	 256 	ASP	D	Protein	S	4
FT	#SUB	177	 177 	ARG	C	258	 258 	HIS	D	Protein	S	5
FT	#SUB	177	 177 	ARG	C	260	 260 	TYR	D	Protein	S	4
FT	#SUB	178	 178 	ARG	C	22	  22 	ARG	D	Protein	S	4
FT	#SUB	178	 178 	ARG	C	195	 195 	PRO	D	Protein	S	8
FT	#SUB	178	 178 	ARG	C	217	 217 	ARG	D	Protein	S	1
FT	#SUB	180	 180 	ILE	C	184	 184 	TRP	D	Protein	S	8
FT	#SUB	180	 180 	ILE	C	217	 217 	ARG	D	Protein	S	1
FT	#SUB	182	 182 	SER	C	184	 184 	TRP	D	Protein	S	1
FT	#SUB	184	 184 	TRP	C	180	 180 	ILE	D	Protein	S	7
FT	#SUB	184	 184 	TRP	C	182	 182 	SER	D	Protein	S	1
FT	#SUB	184	 184 	TRP	C	200	 200 	MET	D	Protein	S	2
FT	#SUB	185	 185 	ASN	C	152	 152 	TRP	D	Protein	S	4
FT	#SUB	186	 186 	PRO	C	152	 152 	TRP	D	Protein	S	9
FT	#SUB	186	 186 	PRO	C	160	 160 	ILE	D	Protein	B	2
FT	#SUB	186	 186 	PRO	C	162	 162 	GLN	D	Protein	S	2
FT	#SUB	187	 187 	GLU	C	154	 154 	THR	D	Protein	S	8
FT	#SUB	187	 187 	GLU	C	155	 155 	LYS	D	Protein	S	8
FT	#SUB	187	 187 	GLU	C	160	 160 	ILE	D	Protein	B	2
FT	#SUB	195	 195 	PRO	C	178	 178 	ARG	D	Protein	S	7
FT	#SUB	199	 199 	THR	C	180	 180 	ILE	D	Protein	S	1
FT	#SUB	199	 199 	THR	C	200	 200 	MET	D	Protein	S	4
FT	#SUB	200	 200 	MET	C	199	 199 	THR	D	Protein	S	2
FT	#SUB	200	 200 	MET	C	200	 200 	MET	D	Protein	S	4
FT	#SUB	202	 202 	GLN	C	31	  31 	PHE	D	Protein	A	2
FT	#SUB	202	 202 	GLN	C	215	 215 	TYR	D	Protein	S	3
FT	#SUB	202	 202 	GLN	C	217	 217 	ARG	D	Protein	S	9
FT	#SUB	202	 202 	GLN	C	255	 255 	GLY	D	Protein	S	1
FT	#SUB	204	 204 	TYR	C	17	  17 	HIS	D	Protein	S	1
FT	#SUB	204	 204 	TYR	C	19	  19 	LYS	D	Protein	S	9
FT	#SUB	204	 204 	TYR	C	29	  29 	SER	D	Protein	S	5
FT	#SUB	204	 204 	TYR	C	31	  31 	PHE	D	Protein	S	13
FT	#SUB	204	 204 	TYR	C	256	 256 	ASP	D	Protein	S	2
FT	#SUB	205	 205 	VAL	C	19	  19 	LYS	D	Protein	B	4
FT	#SUB	206	 206 	ASN	C	17	  17 	HIS	D	Protein	S	4
FT	#SUB	206	 206 	ASN	C	18	  18 	PHE	D	Protein	S	1
FT	#SUB	211	 211 	SER	C	31	  31 	PHE	D	Protein	S	1
FT	#SUB	212	 212 	CYS	C	31	  31 	PHE	D	Protein	B	3
FT	#SUB	213	 213 	GLN	C	31	  31 	PHE	D	Protein	A	4
FT	#SUB	213	 213 	GLN	C	32	  32 	GLY	D	Protein	S	1
FT	#SUB	213	 213 	GLN	C	215	 215 	TYR	D	Protein	S	10
FT	#SUB	213	 213 	GLN	C	253	 253 	THR	D	Protein	S	1
FT	#SUB	213	 213 	GLN	C	254	 254 	LEU	D	Protein	S	4
FT	#SUB	213	 213 	GLN	C	255	 255 	GLY	D	Protein	S	2
FT	#SUB	215	 215 	TYR	C	202	 202 	GLN	D	Protein	S	5
FT	#SUB	215	 215 	TYR	C	213	 213 	GLN	D	Protein	S	8
FT	#SUB	217	 217 	ARG	C	177	 177 	ARG	D	Protein	S	7
FT	#SUB	217	 217 	ARG	C	180	 180 	ILE	D	Protein	S	3
FT	#SUB	217	 217 	ARG	C	202	 202 	GLN	D	Protein	A	11
FT	#SUB	218	 218 	SER	C	177	 177 	ARG	D	Protein	S	6
FT	#SUB	251	 251 	VAL	C	31	  31 	PHE	D	Protein	S	1
FT	#SUB	251	 251 	VAL	C	32	  32 	GLY	D	Protein	S	1
FT	#SUB	253	 253 	THR	C	34	  34 	GLN	D	Protein	S	1
FT	#SUB	253	 253 	THR	C	213	 213 	GLN	D	Protein	S	1
FT	#SUB	253	 253 	THR	C	253	 253 	THR	D	Protein	S	3
FT	#SUB	254	 254 	LEU	C	213	 213 	GLN	D	Protein	B	4
FT	#SUB	255	 255 	GLY	C	202	 202 	GLN	D	Protein	B	1
FT	#SUB	255	 255 	GLY	C	213	 213 	GLN	D	Protein	B	2
FT	#SUB	256	 256 	ASP	C	177	 177 	ARG	D	Protein	S	4
FT	#SUB	256	 256 	ASP	C	204	 204 	TYR	D	Protein	S	3
FT	#SUB	258	 258 	HIS	C	177	 177 	ARG	D	Protein	S	7
FT	#HET	177	 177 	ARG	C	4	401 	UFP	D	S	14
FT	#HET	178	 178 	ARG	C	4	401 	UFP	D	S	5
FT	#HET	217	 217 	ARG	C	5	402 	SO4	D	S	6
FT	#HET	218	 218 	SER	C	5	402 	SO4	D	S	2
FT	DISORDER	98	118
FT	DISORDER	314	315
CC	SEQUENCE	292 AA (ATOM);
CC	MEEAYLALGK KILEEGHFKE DRTGTGTYSL FGYQMRFDLA KGFPLLTTKR VPFGLIKSEL
CC	LWFLKGDTNI RYLLERNNHI WDEWAFERYV KSADYQGEEH QKFCDAILND AEFAEKYGEL
CC	GNIYGAQWRH WETKDGSFID QLANVIEMIK TNPDSRRLIV SAWNPEDVPS MALPPCHTMF
CC	QFYVNEGKLS CQLYQRSADV FLGVPFNIAS YALLTHLIAH ETGLEVGEFV HTLGDAHLYQ
CC	NHVEQMQEQL SREVRSFPTL VLNPDKASVF DFDMEDIKVE GYDPHPTIKA PI
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MEEAYLALGKKILEEGHFKEDRTGTGTYSLFGYQMRFDLAKGFPLLTTKR
CC	ATOM   MEEAYLALGKKILEEGHFKEDRTGTGTYSLFGYQMRFDLAKGFPLLTTKR
CC	       **************************************************
CC	SEQRES VPFGLIKSELLWFLKGDTNIRYLLERNNHIWDEWAFERYVKSADYQGPDM
CC	ATOM   VPFGLIKSELLWFLKGDTNIRYLLERNNHIWDEWAFERYVKSADYQG---
CC	       ***********************************************   
CC	SEQRES TDFGHRVLQDPAFAEQYKEEHQKFCDAILNDAEFAEKYGELGNIYGAQWR
CC	ATOM   ------------------EEHQKFCDAILNDAEFAEKYGELGNIYGAQWR
CC	                         ********************************
CC	SEQRES HWETKDGSFIDQLANVIEMIKTNPDSRRLIVSAWNPEDVPSMALPPCHTM
CC	ATOM   HWETKDGSFIDQLANVIEMIKTNPDSRRLIVSAWNPEDVPSMALPPCHTM
CC	       **************************************************
CC	SEQRES FQFYVNEGKLSCQLYQRSADVFLGVPFNIASYALLTHLIAHETGLEVGEF
CC	ATOM   FQFYVNEGKLSCQLYQRSADVFLGVPFNIASYALLTHLIAHETGLEVGEF
CC	       **************************************************
CC	SEQRES VHTLGDAHLYQNHVEQMQEQLSREVRSFPTLVLNPDKASVFDFDMEDIKV
CC	ATOM   VHTLGDAHLYQNHVEQMQEQLSREVRSFPTLVLNPDKASVFDFDMEDIKV
CC	       **************************************************
CC	SEQRES EGYDPHPTIKAPIAV
CC	ATOM   EGYDPHPTIKAPI--
CC	       *************  
SQ	SEQUENCE	315 AA;      MW;         CN;
	MEEAYLALGK KILEEGHFKE DRTGTGTYSL FGYQMRFDLA KGFPLLTTKR VPFGLIKSEL
	LWFLKGDTNI RYLLERNNHI WDEWAFERYV KSADYQGPDM TDFGHRVLQD PAFAEQYKEE
	HQKFCDAILN DAEFAEKYGE LGNIYGAQWR HWETKDGSFI DQLANVIEMI KTNPDSRRLI
	VSAWNPEDVP SMALPPCHTM FQFYVNEGKL SCQLYQRSAD VFLGVPFNIA SYALLTHLIA
	HETGLEVGEF VHTLGDAHLY QNHVEQMQEQ LSREVRSFPT LVLNPDKASV FDFDMEDIKV
	EGYDPHPTIK APIAV
//
ID	6QXSD	STANDARD;	PRT;	315	AA.
DT	CONVERTED FROM PDB (SEQRES) 6QXS
DE	Thymidylate synthase
OS	Enterococcus faecalis
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.880
CC	R-Factor	0.203
FT	#SUB	172	 172 	THR	D	186	 186 	PRO	A	Protein	S	1
FT	#SUB	172	 172 	THR	D	187	 187 	GLU	A	Protein	S	1
FT	#SUB	172	 172 	THR	D	190	 190 	PRO	A	Protein	S	5
FT	#SUB	172	 172 	THR	D	191	 191 	SER	A	Protein	B	1
FT	#SUB	158	 158 	SER	D	171	 171 	LYS	B	Protein	S	3
FT	#SUB	158	 158 	SER	D	242	 242 	GLU	B	Protein	S	2
FT	#SUB	158	 158 	SER	D	243	 243 	THR	B	Protein	S	3
FT	#SUB	159	 159 	PHE	D	171	 171 	LYS	B	Protein	A	9
FT	#SUB	159	 159 	PHE	D	242	 242 	GLU	B	Protein	S	6
FT	#SUB	159	 159 	PHE	D	288	 288 	ALA	B	Protein	S	1
FT	#SUB	160	 160 	ILE	D	168	 168 	GLU	B	Protein	A	3
FT	#SUB	160	 160 	ILE	D	172	 172 	THR	B	Protein	S	1
FT	#SUB	161	 161 	ASP	D	168	 168 	GLU	B	Protein	A	7
FT	#SUB	165	 165 	ASN	D	168	 168 	GLU	B	Protein	S	6
FT	#SUB	168	 168 	GLU	D	160	 160 	ILE	B	Protein	S	2
FT	#SUB	168	 168 	GLU	D	161	 161 	ASP	B	Protein	S	6
FT	#SUB	168	 168 	GLU	D	165	 165 	ASN	B	Protein	S	7
FT	#SUB	171	 171 	LYS	D	158	 158 	SER	B	Protein	S	1
FT	#SUB	171	 171 	LYS	D	159	 159 	PHE	B	Protein	S	6
FT	#SUB	172	 172 	THR	D	160	 160 	ILE	B	Protein	S	1
FT	#SUB	242	 242 	GLU	D	158	 158 	SER	B	Protein	B	3
FT	#SUB	242	 242 	GLU	D	159	 159 	PHE	B	Protein	S	2
FT	#SUB	243	 243 	THR	D	158	 158 	SER	B	Protein	B	4
FT	#SUB	244	 244 	GLY	D	157	 157 	GLY	B	Protein	B	1
FT	#SUB	288	 288 	ALA	D	151	 151 	HIS	B	Protein	S	1
FT	#SUB	288	 288 	ALA	D	159	 159 	PHE	B	Protein	B	1
FT	#SUB	17	  17 	HIS	D	204	 204 	TYR	C	Protein	S	1
FT	#SUB	17	  17 	HIS	D	206	 206 	ASN	C	Protein	S	4
FT	#SUB	18	  18 	PHE	D	206	 206 	ASN	C	Protein	B	1
FT	#SUB	19	  19 	LYS	D	175	 175 	ASP	C	Protein	S	3
FT	#SUB	19	  19 	LYS	D	204	 204 	TYR	C	Protein	S	9
FT	#SUB	19	  19 	LYS	D	205	 205 	VAL	C	Protein	S	4
FT	#SUB	20	  20 	GLU	D	175	 175 	ASP	C	Protein	A	5
FT	#SUB	21	  21 	ASP	D	177	 177 	ARG	C	Protein	S	3
FT	#SUB	22	  22 	ARG	D	178	 178 	ARG	C	Protein	S	4
FT	#SUB	29	  29 	SER	D	204	 204 	TYR	C	Protein	A	5
FT	#SUB	31	  31 	PHE	D	36	  36 	ARG	C	Protein	B	3
FT	#SUB	31	  31 	PHE	D	202	 202 	GLN	C	Protein	S	2
FT	#SUB	31	  31 	PHE	D	204	 204 	TYR	C	Protein	S	13
FT	#SUB	31	  31 	PHE	D	211	 211 	SER	C	Protein	S	1
FT	#SUB	31	  31 	PHE	D	212	 212 	CYS	C	Protein	S	3
FT	#SUB	31	  31 	PHE	D	213	 213 	GLN	C	Protein	S	4
FT	#SUB	31	  31 	PHE	D	251	 251 	VAL	C	Protein	B	1
FT	#SUB	32	  32 	GLY	D	34	  34 	GLN	C	Protein	B	3
FT	#SUB	32	  32 	GLY	D	36	  36 	ARG	C	Protein	B	4
FT	#SUB	32	  32 	GLY	D	213	 213 	GLN	C	Protein	B	1
FT	#SUB	32	  32 	GLY	D	251	 251 	VAL	C	Protein	B	1
FT	#SUB	33	  33 	TYR	D	34	  34 	GLN	C	Protein	B	11
FT	#SUB	34	  34 	GLN	D	32	  32 	GLY	C	Protein	S	1
FT	#SUB	34	  34 	GLN	D	33	  33 	TYR	C	Protein	S	8
FT	#SUB	34	  34 	GLN	D	34	  34 	GLN	C	Protein	A	5
FT	#SUB	34	  34 	GLN	D	253	 253 	THR	C	Protein	S	1
FT	#SUB	36	  36 	ARG	D	31	  31 	PHE	C	Protein	S	4
FT	#SUB	36	  36 	ARG	D	32	  32 	GLY	C	Protein	S	3
FT	#SUB	152	 152 	TRP	D	185	 185 	ASN	C	Protein	S	4
FT	#SUB	152	 152 	TRP	D	186	 186 	PRO	C	Protein	S	9
FT	#SUB	153	 153 	GLU	D	155	 155 	LYS	C	Protein	S	1
FT	#SUB	154	 154 	THR	D	155	 155 	LYS	C	Protein	B	2
FT	#SUB	154	 154 	THR	D	187	 187 	GLU	C	Protein	A	8
FT	#SUB	155	 155 	LYS	D	154	 154 	THR	C	Protein	S	1
FT	#SUB	155	 155 	LYS	D	187	 187 	GLU	C	Protein	A	8
FT	#SUB	160	 160 	ILE	D	186	 186 	PRO	C	Protein	S	2
FT	#SUB	160	 160 	ILE	D	187	 187 	GLU	C	Protein	S	2
FT	#SUB	162	 162 	GLN	D	186	 186 	PRO	C	Protein	S	2
FT	#SUB	173	 173 	ASN	D	22	  22 	ARG	C	Protein	S	1
FT	#SUB	175	 175 	ASP	D	19	  19 	LYS	C	Protein	S	4
FT	#SUB	177	 177 	ARG	D	217	 217 	ARG	C	Protein	A	7
FT	#SUB	177	 177 	ARG	D	218	 218 	SER	C	Protein	S	6
FT	#SUB	177	 177 	ARG	D	256	 256 	ASP	C	Protein	S	4
FT	#SUB	177	 177 	ARG	D	258	 258 	HIS	C	Protein	S	7
FT	#SUB	178	 178 	ARG	D	195	 195 	PRO	C	Protein	S	7
FT	#SUB	180	 180 	ILE	D	184	 184 	TRP	C	Protein	S	7
FT	#SUB	180	 180 	ILE	D	199	 199 	THR	C	Protein	S	1
FT	#SUB	180	 180 	ILE	D	217	 217 	ARG	C	Protein	S	3
FT	#SUB	182	 182 	SER	D	184	 184 	TRP	C	Protein	S	1
FT	#SUB	184	 184 	TRP	D	162	 162 	GLN	C	Protein	S	1
FT	#SUB	184	 184 	TRP	D	180	 180 	ILE	C	Protein	S	8
FT	#SUB	184	 184 	TRP	D	182	 182 	SER	C	Protein	S	1
FT	#SUB	186	 186 	PRO	D	152	 152 	TRP	C	Protein	S	5
FT	#SUB	186	 186 	PRO	D	160	 160 	ILE	C	Protein	B	2
FT	#SUB	186	 186 	PRO	D	162	 162 	GLN	C	Protein	S	2
FT	#SUB	187	 187 	GLU	D	154	 154 	THR	C	Protein	S	9
FT	#SUB	187	 187 	GLU	D	155	 155 	LYS	C	Protein	S	10
FT	#SUB	195	 195 	PRO	D	178	 178 	ARG	C	Protein	S	8
FT	#SUB	199	 199 	THR	D	200	 200 	MET	C	Protein	S	2
FT	#SUB	200	 200 	MET	D	184	 184 	TRP	C	Protein	S	2
FT	#SUB	200	 200 	MET	D	199	 199 	THR	C	Protein	S	4
FT	#SUB	200	 200 	MET	D	200	 200 	MET	C	Protein	S	4
FT	#SUB	202	 202 	GLN	D	31	  31 	PHE	C	Protein	B	1
FT	#SUB	202	 202 	GLN	D	215	 215 	TYR	C	Protein	S	5
FT	#SUB	202	 202 	GLN	D	217	 217 	ARG	C	Protein	S	11
FT	#SUB	202	 202 	GLN	D	255	 255 	GLY	C	Protein	S	1
FT	#SUB	204	 204 	TYR	D	17	  17 	HIS	C	Protein	S	2
FT	#SUB	204	 204 	TYR	D	19	  19 	LYS	C	Protein	S	4
FT	#SUB	204	 204 	TYR	D	29	  29 	SER	C	Protein	S	4
FT	#SUB	204	 204 	TYR	D	31	  31 	PHE	C	Protein	S	13
FT	#SUB	204	 204 	TYR	D	256	 256 	ASP	C	Protein	S	3
FT	#SUB	205	 205 	VAL	D	19	  19 	LYS	C	Protein	B	3
FT	#SUB	206	 206 	ASN	D	17	  17 	HIS	C	Protein	S	12
FT	#SUB	206	 206 	ASN	D	19	  19 	LYS	C	Protein	S	1
FT	#SUB	212	 212 	CYS	D	31	  31 	PHE	C	Protein	B	2
FT	#SUB	213	 213 	GLN	D	31	  31 	PHE	C	Protein	A	4
FT	#SUB	213	 213 	GLN	D	32	  32 	GLY	C	Protein	S	1
FT	#SUB	213	 213 	GLN	D	215	 215 	TYR	C	Protein	S	8
FT	#SUB	213	 213 	GLN	D	253	 253 	THR	C	Protein	S	1
FT	#SUB	213	 213 	GLN	D	254	 254 	LEU	C	Protein	S	4
FT	#SUB	213	 213 	GLN	D	255	 255 	GLY	C	Protein	S	2
FT	#SUB	215	 215 	TYR	D	202	 202 	GLN	C	Protein	S	3
FT	#SUB	215	 215 	TYR	D	213	 213 	GLN	C	Protein	S	10
FT	#SUB	217	 217 	ARG	D	177	 177 	ARG	C	Protein	S	5
FT	#SUB	217	 217 	ARG	D	178	 178 	ARG	C	Protein	S	1
FT	#SUB	217	 217 	ARG	D	180	 180 	ILE	C	Protein	S	1
FT	#SUB	217	 217 	ARG	D	202	 202 	GLN	C	Protein	A	9
FT	#SUB	218	 218 	SER	D	177	 177 	ARG	C	Protein	S	2
FT	#SUB	253	 253 	THR	D	34	  34 	GLN	C	Protein	S	1
FT	#SUB	253	 253 	THR	D	213	 213 	GLN	C	Protein	S	1
FT	#SUB	253	 253 	THR	D	253	 253 	THR	C	Protein	S	3
FT	#SUB	254	 254 	LEU	D	213	 213 	GLN	C	Protein	B	4
FT	#SUB	255	 255 	GLY	D	202	 202 	GLN	C	Protein	B	1
FT	#SUB	255	 255 	GLY	D	213	 213 	GLN	C	Protein	B	2
FT	#SUB	256	 256 	ASP	D	177	 177 	ARG	C	Protein	S	4
FT	#SUB	256	 256 	ASP	D	204	 204 	TYR	C	Protein	S	2
FT	#SUB	258	 258 	HIS	D	177	 177 	ARG	C	Protein	S	5
FT	#SUB	260	 260 	TYR	D	177	 177 	ARG	C	Protein	S	4
FT	#HET	22	  22 	ARG	D	4	401 	UFP	D	S	11
FT	#HET	52	  52 	PRO	D	6	403 	FFO	D	S	1
FT	#HET	55	  55 	LEU	D	6	403 	FFO	D	S	2
FT	#HET	80	  80 	ILE	D	6	403 	FFO	D	A	9
FT	#HET	81	  81 	TRP	D	4	401 	UFP	D	S	1
FT	#HET	81	  81 	TRP	D	6	403 	FFO	D	S	4
FT	#HET	84	  84 	TRP	D	6	403 	FFO	D	S	7
FT	#HET	145	 145 	TYR	D	4	401 	UFP	D	S	7
FT	#HET	177	 177 	ARG	D	5	402 	SO4	D	A	14
FT	#HET	178	 178 	ARG	D	5	402 	SO4	D	S	7
FT	#HET	194	 194 	LEU	D	6	403 	FFO	D	S	2
FT	#HET	197	 197 	CYS	D	4	401 	UFP	D	S	19
FT	#HET	198	 198 	HIS	D	4	401 	UFP	D	S	6
FT	#HET	216	 216 	GLN	D	4	401 	UFP	D	S	3
FT	#HET	217	 217 	ARG	D	4	401 	UFP	D	S	8
FT	#HET	218	 218 	SER	D	4	401 	UFP	D	A	9
FT	#HET	220	 220 	ASP	D	4	401 	UFP	D	A	4
FT	#HET	220	 220 	ASP	D	6	403 	FFO	D	S	9
FT	#HET	223	 223 	LEU	D	6	403 	FFO	D	A	2
FT	#HET	224	 224 	GLY	D	6	403 	FFO	D	B	2
FT	#HET	227	 227 	PHE	D	6	403 	FFO	D	S	2
FT	#HET	228	 228 	ASN	D	4	401 	UFP	D	S	4
FT	#HET	228	 228 	ASN	D	6	403 	FFO	D	S	1
FT	#HET	258	 258 	HIS	D	4	401 	UFP	D	S	4
FT	#HET	260	 260 	TYR	D	4	401 	UFP	D	S	4
FT	#HET	309	 309 	ILE	D	6	403 	FFO	D	B	1
FT	#HET	313	 313 	ILE	D	6	403 	FFO	D	S	4
FT	#HET	314	 314 	ALA	D	6	403 	FFO	D	A	7
CC	SEQUENCE	315 AA (ATOM);
CC	MEEAYLALGK KILEEGHFKE DRTGTGTYSL FGYQMRFDLA KGFPLLTTKR VPFGLIKSEL
CC	LWFLKGDTNI RYLLERNNHI WDEWAFERYV KSADYQGPDM TDFGHRVLQD PAFAEQYKEE
CC	HQKFCDAILN DAEFAEKYGE LGNIYGAQWR HWETKDGSFI DQLANVIEMI KTNPDSRRLI
CC	VSAWNPEDVP SMALPPCHTM FQFYVNEGKL SCQLYQRSAD VFLGVPFNIA SYALLTHLIA
CC	HETGLEVGEF VHTLGDAHLY QNHVEQMQEQ LSREVRSFPT LVLNPDKASV FDFDMEDIKV
CC	EGYDPHPTIK APIAV
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MEEAYLALGKKILEEGHFKEDRTGTGTYSLFGYQMRFDLAKGFPLLTTKR
CC	ATOM   MEEAYLALGKKILEEGHFKEDRTGTGTYSLFGYQMRFDLAKGFPLLTTKR
CC	       **************************************************
CC	SEQRES VPFGLIKSELLWFLKGDTNIRYLLERNNHIWDEWAFERYVKSADYQGPDM
CC	ATOM   VPFGLIKSELLWFLKGDTNIRYLLERNNHIWDEWAFERYVKSADYQGPDM
CC	       **************************************************
CC	SEQRES TDFGHRVLQDPAFAEQYKEEHQKFCDAILNDAEFAEKYGELGNIYGAQWR
CC	ATOM   TDFGHRVLQDPAFAEQYKEEHQKFCDAILNDAEFAEKYGELGNIYGAQWR
CC	       **************************************************
CC	SEQRES HWETKDGSFIDQLANVIEMIKTNPDSRRLIVSAWNPEDVPSMALPPCHTM
CC	ATOM   HWETKDGSFIDQLANVIEMIKTNPDSRRLIVSAWNPEDVPSMALPPCHTM
CC	       **************************************************
CC	SEQRES FQFYVNEGKLSCQLYQRSADVFLGVPFNIASYALLTHLIAHETGLEVGEF
CC	ATOM   FQFYVNEGKLSCQLYQRSADVFLGVPFNIASYALLTHLIAHETGLEVGEF
CC	       **************************************************
CC	SEQRES VHTLGDAHLYQNHVEQMQEQLSREVRSFPTLVLNPDKASVFDFDMEDIKV
CC	ATOM   VHTLGDAHLYQNHVEQMQEQLSREVRSFPTLVLNPDKASVFDFDMEDIKV
CC	       **************************************************
CC	SEQRES EGYDPHPTIKAPIAV
CC	ATOM   EGYDPHPTIKAPIAV
CC	       ***************
SQ	SEQUENCE	315 AA;      MW;         CN;
	MEEAYLALGK KILEEGHFKE DRTGTGTYSL FGYQMRFDLA KGFPLLTTKR VPFGLIKSEL
	LWFLKGDTNI RYLLERNNHI WDEWAFERYV KSADYQGPDM TDFGHRVLQD PAFAEQYKEE
	HQKFCDAILN DAEFAEKYGE LGNIYGAQWR HWETKDGSFI DQLANVIEMI KTNPDSRRLI
	VSAWNPEDVP SMALPPCHTM FQFYVNEGKL SCQLYQRSAD VFLGVPFNIA SYALLTHLIA
	HETGLEVGEF VHTLGDAHLY QNHVEQMQEQ LSREVRSFPT LVLNPDKASV FDFDMEDIKV
	EGYDPHPTIK APIAV
//