Brand  (β version)

PDB ID: 4KJQ

Hetero Atom Contents

  The number of atoms exceeds 100,000.
  So, it can not be displayed here.

Select unit:

Select hetatm:   

close
information
centroid:
interaction residue:

Select chain:   Sequence  

Data format:   

Color scheme of protein:

Ligands
Code Name Style Show Link
F Fluoride ion PoSSuM
Non-standard Residues
Code Name Show
Glycosylation
Code Name Emphasize
Modification
Code Name Show

Structure summary

Code : 4KJQ   PDBj   RCSB PDB   PDBe
Header : tranport protein, membrane protein
Title : Structure of the CLC-ec1 deltaNC construct in 100mM fluoride
Release Data : 2013-08-21
Compound :
mol_id molecule chains synonym
1 H(+)/Cl(-) exchange transporter ClcA A,B ClC-ec1
fragment: unp residues 17-460
mol_id molecule chains
2 Fab, heavy chain C,E
mol_id molecule chains
3 Fab, light chain D,F
Source :
mol_id organism_scientific expression_system
1 Escherichia coli  (taxid:83333) Escherichia coli  (taxid:562)
strain: K12
gene: b0155, clcA, eriC, JW5012, yadQ
mol_id organism_scientific organism_common expression_system
2 Mus musculus  (taxid:10090) Mouse MUS MUSCULUS  (taxid:10090)
expression_system_cell_line: hybridoma
mol_id organism_scientific organism_common expression_system
3 Mus musculus  (taxid:10090) Mouse MUS MUSCULUS  (taxid:10090)
expression_system_cell_line: hybridoma
Authors : Lim, H.-H., Miller, C.
Keywords : membrane transporter, fluoride, tranport protein, membrane protein
Exp. method : X-RAY DIFFRACTION ( 2.875 Å )
Citation :

Fluoride-dependent interruption of the transport cycle of a CLC Cl(-)/H(+) antiporter.

Lim, H.H.,Stockbridge, R.B.,Miller, C.
(2013)  Nat.Chem.Biol.  9 : 721 - 725

PubMed: 24036509
DOI: 10.1038/nchembio.1336

Reaction

Chain : A, B
UniProt : P37019 (CLCA_ECOLI)
Reaction: EC: Evidence:
Physiological Direction:
2 chloride(in) + H(+)(out) = 2 chloride(out) + H(+)(in) - HAMAP-Rule:MF_01128, PubMed:14985752, PubMed:16905147
-