PDB ID: 4E6D
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Structure summary
Code : | 4E6D PDBj RCSB PDB PDBe | ||||||||||||
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Header : | TRANSFERASE/TRANSFERASE INHIBITOR | ||||||||||||
Title : | JAK2 kinase (JH1 domain) triple mutant in complex with compound 7 | ||||||||||||
Release Data : | 2012-05-30 | ||||||||||||
Compound : |
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Source : |
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Authors : | Murray, J.M. | ||||||||||||
Keywords : | JAK2, kinase, transferase, phosphorylation, TRANSFERASE-TRANSFERASE INHIBITOR complex | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.22 Å ) | ||||||||||||
Citation : |
Identification of Imidazo-Pyrrolopyridines as Novel and Potent JAK1 Inhibitors.
Kulagowski, J.J.,Blair, W.,Bull, R.J.
et al.
PubMed: 22591402 |
Reaction
Chain : | A, B | ||||||||
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UniProt : | O60674 (JAK2_HUMAN) | ||||||||
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