PDB ID: 4DCE
Hetero Atom Contents
The number of atoms exceeds 100,000. So, it can not be displayed here.
Select unit:
Select hetatm:
Select chain: Sequence
Data format:
Color scheme of protein:
Structure summary
Code : | 4DCE PDBj RCSB PDB PDBe | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Header : | Transferase/Inhibitor | ||||||||||||
Title : | Crystal structure of human anaplastic lymphoma kinase in complex with a piperidine-carboxamide inhibitor | ||||||||||||
Release Data : | 2012-02-08 | ||||||||||||
Compound : |
|
||||||||||||
Source : |
|
||||||||||||
Authors : | Whittington, D.A., Epstein, L.F., Chen, H. | ||||||||||||
Keywords : | receptor tyrosine kinase, inhibitor, NPM-ALK, EML4-ALK, Transferase-Inhibitor complex | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.03 Å ) | ||||||||||||
Citation : |
Rapid development of piperidine carboxamides as potent and selective anaplastic lymphoma kinase inhibitors.
Bryan, M.C.,Whittington, D.A.,Doherty, E.M.
et al.
PubMed: 22263917 |
Reaction
Chain : | A, B | ||||||||
---|---|---|---|---|---|---|---|---|---|
UniProt : | Q9UM73 (ALK_HUMAN) | ||||||||
|