ID	4DCEA	STANDARD;	PRT;	333	AA.
DT	CONVERTED FROM PDB (SEQRES) 4DCE
DE	ALK tyrosine kinase receptor
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.030
CC	R-Factor	0.211
FT	#SUB	41	1118 	LEU	A	212	1289 	ALA	B	Protein	S	1
FT	#SUB	41	1118 	LEU	A	213	1290 	MET	B	Protein	A	4
FT	#SUB	42	1119 	ILE	A	213	1290 	MET	B	Protein	B	4
FT	#SUB	43	1120 	ARG	A	83	1160 	ASP	B	Protein	S	1
FT	#SUB	43	1120 	ARG	A	213	1290 	MET	B	Protein	B	2
FT	#SUB	52	1129 	GLU	A	211	1288 	CYS	B	Protein	S	1
FT	#SUB	52	1129 	GLU	A	212	1289 	ALA	B	Protein	S	1
FT	#SUB	54	1131 	TYR	A	211	1288 	CYS	B	Protein	S	3
FT	#SUB	54	1131 	TYR	A	212	1289 	ALA	B	Protein	S	6
FT	#SUB	77	1154 	GLU	A	257	1334 	SER	B	Protein	S	6
FT	#SUB	77	1154 	GLU	A	258	1335 	ASN	B	Protein	S	1
FT	#SUB	77	1154 	GLU	A	259	1336 	GLN	B	Protein	S	10
FT	#SUB	78	1155 	VAL	A	259	1336 	GLN	B	Protein	S	3
FT	#SUB	113	1190 	LEU	A	257	1334 	SER	B	Protein	A	2
FT	#SUB	113	1190 	LEU	A	260	1337 	GLU	B	Protein	S	1
FT	#HET	45	1122 	LEU	A	1	1501 	0JF	A	A	3
FT	#HET	53	1130 	VAL	A	1	1501 	0JF	A	S	3
FT	#HET	71	1148 	ALA	A	1	1501 	0JF	A	S	3
FT	#HET	73	1150 	LYS	A	1	1501 	0JF	A	S	4
FT	#HET	90	1167 	GLU	A	1	1501 	0JF	A	S	2
FT	#HET	94	1171 	ILE	A	1	1501 	0JF	A	S	10
FT	#HET	97	1174 	PHE	A	1	1501 	0JF	A	S	2
FT	#HET	102	1179 	ILE	A	1	1501 	0JF	A	S	1
FT	#HET	103	1180 	VAL	A	1	1501 	0JF	A	A	3
FT	#HET	119	1196 	LEU	A	1	1501 	0JF	A	S	3
FT	#HET	120	1197 	GLU	A	1	1501 	0JF	A	B	2
FT	#HET	122	1199 	MET	A	1	1501 	0JF	A	A	15
FT	#HET	123	1200 	ALA	A	1	1501 	0JF	A	B	2
FT	#HET	125	1202 	GLY	A	1	1501 	0JF	A	B	7
FT	#HET	126	1203 	ASP	A	1	1501 	0JF	A	S	1
FT	#HET	179	1256 	LEU	A	1	1501 	0JF	A	S	6
FT	#HET	191	1268 	ILE	A	1	1501 	0JF	A	B	1
FT	#HET	192	1269 	GLY	A	1	1501 	0JF	A	B	12
FT	#HET	193	1270 	ASP	A	1	1501 	0JF	A	A	9
FT	#HET	194	1271 	PHE	A	1	1501 	0JF	A	A	9
FT	DISORDER	1	15
FT	DISORDER	48	50
FT	DISORDER	60	64
FT	DISORDER	196	209
FT	DISORDER	326	333
CC	SEQUENCE	288 AA (ATOM);
CC	NPNYSFAGKT SSISDLKEVP RKNITLIRGL GHGEVYEGQV SPSPLQVAVK TLPEVCSEQD
CC	ELDFLMEALI ISKFNHQNIV RCIGVSLQSL PRFILLELMA GGDLKSFLRE TRPRPSQPSS
CC	LAMLDLLHVA RDIACGCQYL EENHFIHRDI AARNCLLTCP GPGRVAKIGD FGGCAMLPVK
CC	WMPPEAFMEG IFTSKTDTWS FGVLLWEIFS LGYMPYPSKS NQEVLEFVTS GGRMDPPKNC
CC	PGPVYRIMTQ CWQHQPEDRP NFAIILERIE YCTQDPDVIN TALPIEYG
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES YKLSKLRTSTIMTDYNPNYSFAGKTSSISDLKEVPRKNITLIRGLGHGAF
CC	ATOM   ---------------NPNYSFAGKTSSISDLKEVPRKNITLIRGLGH---
CC	                      ********************************   
CC	SEQRES GEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQ
CC	ATOM   GEVYEGQVS-----PSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQ
CC	       *********     ************************************
CC	SEQRES NIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLAMLDLL
CC	ATOM   NIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLAMLDLL
CC	       **************************************************
CC	SEQRES HVARDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDI
CC	ATOM   HVARDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFG-----
CC	       *********************************************     
CC	SEQRES YRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGY
CC	ATOM   ---------GCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGY
CC	                *****************************************
CC	SEQRES MPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFA
CC	ATOM   MPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFA
CC	       **************************************************
CC	SEQRES IILERIEYCTQDPDVINTALPIEYGPLVEEEEK
CC	ATOM   IILERIEYCTQDPDVINTALPIEYG--------
CC	       *************************        
SQ	SEQUENCE	333 AA;      MW;         CN;
	YKLSKLRTST IMTDYNPNYS FAGKTSSISD LKEVPRKNIT LIRGLGHGAF GEVYEGQVSG
	MPNDPSPLQV AVKTLPEVCS EQDELDFLME ALIISKFNHQ NIVRCIGVSL QSLPRFILLE
	LMAGGDLKSF LRETRPRPSQ PSSLAMLDLL HVARDIACGC QYLEENHFIH RDIAARNCLL
	TCPGPGRVAK IGDFGMARDI YRASYYRKGG CAMLPVKWMP PEAFMEGIFT SKTDTWSFGV
	LLWEIFSLGY MPYPSKSNQE VLEFVTSGGR MDPPKNCPGP VYRIMTQCWQ HQPEDRPNFA
	IILERIEYCT QDPDVINTAL PIEYGPLVEE EEK
//
ID	4DCEB	STANDARD;	PRT;	333	AA.
DT	CONVERTED FROM PDB (SEQRES) 4DCE
DE	ALK tyrosine kinase receptor
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.030
CC	R-Factor	0.211
FT	#SUB	83	1160 	ASP	B	43	1120 	ARG	A	Protein	S	1
FT	#SUB	211	1288 	CYS	B	52	1129 	GLU	A	Protein	B	1
FT	#SUB	211	1288 	CYS	B	54	1131 	TYR	A	Protein	A	3
FT	#SUB	212	1289 	ALA	B	41	1118 	LEU	A	Protein	B	1
FT	#SUB	212	1289 	ALA	B	52	1129 	GLU	A	Protein	B	1
FT	#SUB	212	1289 	ALA	B	54	1131 	TYR	A	Protein	A	6
FT	#SUB	213	1290 	MET	B	41	1118 	LEU	A	Protein	S	4
FT	#SUB	213	1290 	MET	B	42	1119 	ILE	A	Protein	S	4
FT	#SUB	213	1290 	MET	B	43	1120 	ARG	A	Protein	S	2
FT	#SUB	257	1334 	SER	B	77	1154 	GLU	A	Protein	S	6
FT	#SUB	257	1334 	SER	B	113	1190 	LEU	A	Protein	S	2
FT	#SUB	258	1335 	ASN	B	77	1154 	GLU	A	Protein	B	1
FT	#SUB	259	1336 	GLN	B	77	1154 	GLU	A	Protein	A	10
FT	#SUB	259	1336 	GLN	B	78	1155 	VAL	A	Protein	S	3
FT	#SUB	260	1337 	GLU	B	113	1190 	LEU	A	Protein	S	1
FT	#HET	45	1122 	LEU	B	2	1501 	0JF	B	A	4
FT	#HET	53	1130 	VAL	B	2	1501 	0JF	B	S	5
FT	#HET	71	1148 	ALA	B	2	1501 	0JF	B	S	3
FT	#HET	73	1150 	LYS	B	2	1501 	0JF	B	S	4
FT	#HET	94	1171 	ILE	B	2	1501 	0JF	B	S	8
FT	#HET	97	1174 	PHE	B	2	1501 	0JF	B	S	2
FT	#HET	102	1179 	ILE	B	2	1501 	0JF	B	S	1
FT	#HET	103	1180 	VAL	B	2	1501 	0JF	B	B	1
FT	#HET	119	1196 	LEU	B	2	1501 	0JF	B	S	3
FT	#HET	120	1197 	GLU	B	2	1501 	0JF	B	B	2
FT	#HET	121	1198 	LEU	B	2	1501 	0JF	B	B	1
FT	#HET	122	1199 	MET	B	2	1501 	0JF	B	A	16
FT	#HET	123	1200 	ALA	B	2	1501 	0JF	B	B	1
FT	#HET	125	1202 	GLY	B	2	1501 	0JF	B	B	9
FT	#HET	126	1203 	ASP	B	2	1501 	0JF	B	A	3
FT	#HET	179	1256 	LEU	B	2	1501 	0JF	B	S	6
FT	#HET	191	1268 	ILE	B	2	1501 	0JF	B	B	1
FT	#HET	192	1269 	GLY	B	2	1501 	0JF	B	B	11
FT	#HET	193	1270 	ASP	B	2	1501 	0JF	B	A	10
FT	#HET	194	1271 	PHE	B	2	1501 	0JF	B	A	8
FT	DISORDER	1	16
FT	DISORDER	48	51
FT	DISORDER	60	65
FT	DISORDER	196	210
FT	DISORDER	326	333
CC	SEQUENCE	284 AA (ATOM);
CC	PNYSFAGKTS SISDLKEVPR KNITLIRGLG HEVYEGQVSS PLQVAVKTLP EVCSEQDELD
CC	FLMEALIISK FNHQNIVRCI GVSLQSLPRF ILLELMAGGD LKSFLRETRP RPSQPSSLAM
CC	LDLLHVARDI ACGCQYLEEN HFIHRDIAAR NCLLTCPGPG RVAKIGDFGC AMLPVKWMPP
CC	EAFMEGIFTS KTDTWSFGVL LWEIFSLGYM PYPSKSNQEV LEFVTSGGRM DPPKNCPGPV
CC	YRIMTQCWQH QPEDRPNFAI ILERIEYCTQ DPDVINTALP IEYG
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES YKLSKLRTSTIMTDYNPNYSFAGKTSSISDLKEVPRKNITLIRGLGHGAF
CC	ATOM   ----------------PNYSFAGKTSSISDLKEVPRKNITLIRGLGH---
CC	                       *******************************   
CC	SEQRES GEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQ
CC	ATOM   -EVYEGQVS------SPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQ
CC	        ********      ***********************************
CC	SEQRES NIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLAMLDLL
CC	ATOM   NIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLAMLDLL
CC	       **************************************************
CC	SEQRES HVARDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDI
CC	ATOM   HVARDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFG-----
CC	       *********************************************     
CC	SEQRES YRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGY
CC	ATOM   ----------CAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGY
CC	                 ****************************************
CC	SEQRES MPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFA
CC	ATOM   MPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFA
CC	       **************************************************
CC	SEQRES IILERIEYCTQDPDVINTALPIEYGPLVEEEEK
CC	ATOM   IILERIEYCTQDPDVINTALPIEYG--------
CC	       *************************        
SQ	SEQUENCE	333 AA;      MW;         CN;
	YKLSKLRTST IMTDYNPNYS FAGKTSSISD LKEVPRKNIT LIRGLGHGAF GEVYEGQVSG
	MPNDPSPLQV AVKTLPEVCS EQDELDFLME ALIISKFNHQ NIVRCIGVSL QSLPRFILLE
	LMAGGDLKSF LRETRPRPSQ PSSLAMLDLL HVARDIACGC QYLEENHFIH RDIAARNCLL
	TCPGPGRVAK IGDFGMARDI YRASYYRKGG CAMLPVKWMP PEAFMEGIFT SKTDTWSFGV
	LLWEIFSLGY MPYPSKSNQE VLEFVTSGGR MDPPKNCPGP VYRIMTQCWQ HQPEDRPNFA
	IILERIEYCT QDPDVINTAL PIEYGPLVEE EEK
//