PDB ID: 4PRJ
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Structure summary
Code : | 4PRJ PDBj RCSB PDB PDBe | ||||||||||||
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Header : | TRANSFERASE/TRANSFERASE INHIBITOR | ||||||||||||
Title : | Aurora A kinase domain with compound 2 (N-[1-(3-cyanobenzyl)-1H-pyrazol-4-yl]-6-(1H-pyrazol-4-yl)-1H-indazole-3-carboxamide) | ||||||||||||
Release Data : | 2014-07-02 | ||||||||||||
Compound : |
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Source : |
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Authors : | Ultsch, M., Eigenbrot, C. | ||||||||||||
Keywords : | protein kinase, phospho-transfer, TRANSFERASE-TRANSFERASE INHIBITOR complex | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.80 Å ) | ||||||||||||
Citation : |
Property- and structure-guided discovery of a tetrahydroindazole series of interleukin-2 inducible T-cell kinase inhibitors.
Burch, J.D.,Lau, K.,Barker, J.J.
et al.
PubMed: 24918870 |
Reaction
Chain : | A | ||||||||||||
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UniProt : | O14965 (AURKA_HUMAN) | ||||||||||||
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