ID	4PRJA	STANDARD;	PRT;	269	AA.
DT	CONVERTED FROM PDB (SEQRES) 4PRJ
DE	Aurora kinase A
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.800
CC	R-Factor	0.233
FT	#HET	15	 137 	ARG	A	1	401 	2VU	A	S	6
FT	#HET	17	 139 	LEU	A	1	401 	2VU	A	A	4
FT	#HET	25	 147 	VAL	A	1	401 	2VU	A	S	1
FT	#HET	38	 160 	ALA	A	1	401 	2VU	A	S	2
FT	#HET	40	 162 	LYS	A	1	401 	2VU	A	S	6
FT	#HET	72	 194 	LEU	A	1	401 	2VU	A	S	3
FT	#HET	88	 210 	LEU	A	1	401 	2VU	A	S	4
FT	#HET	89	 211 	GLU	A	1	401 	2VU	A	B	4
FT	#HET	90	 212 	TYR	A	1	401 	2VU	A	A	12
FT	#HET	91	 213 	ALA	A	1	401 	2VU	A	A	6
FT	#HET	92	 214 	PRO	A	1	401 	2VU	A	B	3
FT	#HET	94	 216 	GLY	A	1	401 	2VU	A	B	8
FT	#HET	98	 220 	ARG	A	1	401 	2VU	A	S	12
FT	#HET	141	 263 	LEU	A	1	401 	2VU	A	S	10
FT	#HET	151	 273 	ALA	A	1	401 	2VU	A	A	5
FT	#HET	152	 274 	ASP	A	1	401 	2VU	A	A	7
FT	DISORDER	1	2
FT	DISORDER	21	23
FT	DISORDER	158	167
FT	DISORDER	267	269
CC	SEQUENCE	251 AA (ATOM);
CC	KRQWALEDFE IGRPLGKGNV YLAREKNSKF ILALKVLFKA QLEKAGVEHQ LRREVEIQSH
CC	LRHPNILRLY GYFHDSTRVY LILEYAPLGT VYRELQKLSK FDEQRTATYI TELANALSYC
CC	HSKKVIHRDI KPENLLLGSA GELKIADFGW SVCGTLDYLP PEMIEGRMHD EKVDLWSLGV
CC	LCYEFLVGKP PFEANTYQDT YKRISRVEFT FPDFVTEGAR DLISRLLKHN PSQRPMLREV
CC	LEHPWITANS S
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MAKRQWALEDFEIGRPLGKGKFGNVYLAREKNSKFILALKVLFKAQLEKA
CC	ATOM   --KRQWALEDFEIGRPLGKG---NVYLAREKNSKFILALKVLFKAQLEKA
CC	         ******************   ***************************
CC	SEQRES GVEHQLRREVEIQSHLRHPNILRLYGYFHDSTRVYLILEYAPLGTVYREL
CC	ATOM   GVEHQLRREVEIQSHLRHPNILRLYGYFHDSTRVYLILEYAPLGTVYREL
CC	       **************************************************
CC	SEQRES QKLSKFDEQRTATYITELANALSYCHSKKVIHRDIKPENLLLGSAGELKI
CC	ATOM   QKLSKFDEQRTATYITELANALSYCHSKKVIHRDIKPENLLLGSAGELKI
CC	       **************************************************
CC	SEQRES ADFGWSVHAPSSRRAALCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEF
CC	ATOM   ADFGWSV----------CGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEF
CC	       *******          *********************************
CC	SEQRES LVGKPPFEANTYQDTYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRP
CC	ATOM   LVGKPPFEANTYQDTYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRP
CC	       **************************************************
CC	SEQRES MLREVLEHPWITANSSKPS
CC	ATOM   MLREVLEHPWITANSS---
CC	       ****************   
SQ	SEQUENCE	269 AA;      MW;         CN;
	MAKRQWALED FEIGRPLGKG KFGNVYLARE KNSKFILALK VLFKAQLEKA GVEHQLRREV
	EIQSHLRHPN ILRLYGYFHD STRVYLILEY APLGTVYREL QKLSKFDEQR TATYITELAN
	ALSYCHSKKV IHRDIKPENL LLGSAGELKI ADFGWSVHAP SSRRAALCGT LDYLPPEMIE
	GRMHDEKVDL WSLGVLCYEF LVGKPPFEAN TYQDTYKRIS RVEFTFPDFV TEGARDLISR
	LLKHNPSQRP MLREVLEHPW ITANSSKPS
//