Brand  (β version)

PDB ID: 4F4C

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Ligands
Code Name Style Show Link
0SA Undecyl 4-O-alpha-D-glucopyranosyl-1-thio-beta-D-glucopyranoside PoSSuM
Non-standard Residues
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Glycosylation
Code Name Emphasize
BMA Beta-D-mannopyranose
MAN Alpha-D-mannopyranose
NAG 2-acetamido-2-deoxy-beta-D-glucopyranose
Modification
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Structure summary

Code : 4F4C   PDBj   RCSB PDB   PDBe
Header : HYDROLASE,PROTEIN TRANSPORT
Title : The Crystal Structure of the Multi-Drug Transporter
Release Data : 2012-09-26
Compound :
mol_id molecule chains synonym
1 Multidrug resistance protein pgp-1 A P-glycoprotein A, P-glycoprotein-related protein 1
ec: 3.6.3.44
Source :
mol_id organism_scientific organism_common expression_system
1 Caenorhabditis elegans  (taxid:6239) Nematode Pichia pastoris  (taxid:4922)
gene: pgp-1, K08E7.9
Authors : Jin, M.S., Oldham, M.L., Zhang, Q., Chen, J.
Keywords : ABC transporter, ATPase, multi-drug transporter, exporter, ATP binding, HYDROLASE, PROTEIN TRANSPORT
Exp. method : X-RAY DIFFRACTION ( 3.40 Å )
Citation :

Crystal structure of the multidrug transporter P-glycoprotein from Caenorhabditis elegans.

Jin, M.S.,Oldham, M.L.,Zhang, Q.  et al.
(2012)  Nature  490 : 566 - 569

PubMed: 23000902
DOI: 10.1038/nature11448

Reaction

Chain : A
UniProt : P34712 (PGP1_CAEEL)
Reaction: EC: Evidence:
Physiological Direction:
ATP + H2O + xenobioticSide 1 = ADP + phosphate + xenobioticSide 2. 7.6.2.2 -
-