ID	4F4CA	STANDARD;	PRT;	1321	AA.
DT	CONVERTED FROM PDB (SEQRES) 4F4C
DE	Multidrug resistance protein pgp-1
OS	Caenorhabditis elegans
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	3.400
CC	R-Factor	0.250
FT	#HET	22	  22 	GLU	A	5	1405 	0SA	A	S	3
FT	#HET	26	  26 	LYS	A	6	1406 	0SA	A	S	1
FT	#HET	903	 903 	ILE	A	5	1405 	0SA	A	S	1
FT	#HET	906	 906 	LEU	A	5	1405 	0SA	A	S	1
FT	#HET	909	 909 	VAL	A	5	1405 	0SA	A	S	1
FT	#HET	910	 910 	ALA	A	5	1405 	0SA	A	S	1
FT	#HET	910	 910 	ALA	A	6	1406 	0SA	A	A	2
FT	#HET	913	 913 	GLN	A	5	1405 	0SA	A	S	5
FT	#HET	913	 913 	GLN	A	6	1406 	0SA	A	A	4
FT	#HET	914	 914 	TYR	A	6	1406 	0SA	A	B	2
FT	#HET	916	 916 	ARG	A	6	1406 	0SA	A	S	8
FT	#HET	917	 917 	GLY	A	6	1406 	0SA	A	B	1
FT	#HET	990	 990 	LEU	A	5	1405 	0SA	A	S	5
FT	#HET	1028	1028 	THR	A	5	1405 	0SA	A	B	3
FT	#HET	1029	1029 	SER	A	5	1405 	0SA	A	A	9
FT	#HET	1031	1031 	LEU	A	5	1405 	0SA	A	A	2
FT	#HET	1032	1032 	GLY	A	5	1405 	0SA	A	B	3
FT	#HET	1032	1032 	GLY	A	6	1406 	0SA	A	B	3
FT	#HET	1035	1035 	THR	A	6	1406 	0SA	A	S	2
FT	#MOD	125	 125 	ASN	A	1	1 	NAG	B	S
FT	DISORDER	1	3
FT	DISORDER	52	54
FT	DISORDER	666	715
FT	DISORDER	1307	1321
CC	SEQUENCE	1250 AA (ATOM);
CC	NGSLRQSLRT LDSFSLAPED VLKTAIKTVE DYEGDNIDSN GEIKITRDEV VNKVSIPQLY
CC	RYTTTLEKLL LFIGTLVAVI TGAGLPLMSI LQGKVSQAFI NEQIVINNNG STFLPTGQNY
CC	TKTDFEHDVM NVVWSYAAMT VGMWAAGQIT VTCYLYVAEQ MNNRLRREFV KSILRQEISW
CC	FDTNHSGTLA TKLFDNLERV KEGTGDKIGM AFQYLSQFIT GFIVAFTHSW QLTLVMLAVT
CC	PIQALCGFAI AKSMSTFAIR ETLRYAKAGK VVEETISSIR TVVSLNGLRY ELERYSTAVE
CC	EAKKAGVLKG LFLGISFGAM QASNFISFAL AFYIGVGWVH DGSLNFGDML TTFSSVMMGS
CC	MALGLAGPQL AVLGTAQGAA SGIYEVLDRK PVIDSSSKAG RKDMKIKGDI TVENVHFTYP
CC	SRPDVPILRG MNLRVNAGQT VALVGSSGCG KSTIISLLLR YYDVLKGKIT IDGVDVRDIN
CC	LEFLRKNVAV VSQEPALFNC TIEENISLGK EGITREEMVA ACKMANAEKF IKTLPNGYNT
CC	LVGDRGTQLS GGQKQRIAIA RALVRNPKIL LLDEATSALD AESEGIVQQA LDKAAKGRTT
CC	IIIAHRLSTI RNADLIISCK NGQVVEVGDH RALMAQQGLY YDLVTAQTFT DAVDSAAEGE
CC	RIGKDALSRL KQELEENNAQ KTNLFEILYH ARPHALSLFI GMSTATIGGF IYPTYSVFFT
CC	SFMNVFAGNP ADFLSQGHFW ALMFLVLAAA QGICSFLMTF FMGIASESLT RDLRNKLFRN
CC	VLSQHIGFFD SPQNASGKIS TRLATDVPNL RTAIDFRFST VITTLVSMVA GIGLAFFYGW
CC	QMALLIIAIL PIVAFGQYLR GRRFTGKNVK SASEFADSGK IAIEAIENVR TVQALAREDT
CC	FYENFCEKLD IPHKEAIKEA FIQGLSYGCA SSVLYLLNTC AYRMGLALII TDPPTMQPMR
CC	VLRVMYAITI STSTLGFATS YFPEYAKATF AGGIIFGMLR KISKIDSLSL AGEKKKLYGK
CC	VIFKNVRFAY PERPEIEILK GLSFSVEPGQ TLALVGPSGC GKSTVVALLE RFYDTLGGEI
CC	FIDGSEIKTL NPEHTRSQIA IVSQEPTLFD CSIAENIIYG LDPSSVTMAQ VEEAARLANI
CC	HNFIAELPEG FETRVGDRGT QLSGGQKQRI AIARALVRNP KILLLDEATS ALDTESEKVV
CC	QEALDRAREG RTCIVIAHRL NTVMNADCIA VVSNGTIIEK GTHTQLMSEK
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MLRNGSLRQSLRTLDSFSLAPEDVLKTAIKTVEDYEGDNIDSNGEIKITR
CC	ATOM   ---NGSLRQSLRTLDSFSLAPEDVLKTAIKTVEDYEGDNIDSNGEIKITR
CC	          ***********************************************
CC	SEQRES DAKEEVVNKVSIPQLYRYTTTLEKLLLFIGTLVAVITGAGLPLMSILQGK
CC	ATOM   D---EVVNKVSIPQLYRYTTTLEKLLLFIGTLVAVITGAGLPLMSILQGK
CC	       *   **********************************************
CC	SEQRES VSQAFINEQIVINNNGSTFLPTGQNYTKTDFEHDVMNVVWSYAAMTVGMW
CC	ATOM   VSQAFINEQIVINNNGSTFLPTGQNYTKTDFEHDVMNVVWSYAAMTVGMW
CC	       **************************************************
CC	SEQRES AAGQITVTCYLYVAEQMNNRLRREFVKSILRQEISWFDTNHSGTLATKLF
CC	ATOM   AAGQITVTCYLYVAEQMNNRLRREFVKSILRQEISWFDTNHSGTLATKLF
CC	       **************************************************
CC	SEQRES DNLERVKEGTGDKIGMAFQYLSQFITGFIVAFTHSWQLTLVMLAVTPIQA
CC	ATOM   DNLERVKEGTGDKIGMAFQYLSQFITGFIVAFTHSWQLTLVMLAVTPIQA
CC	       **************************************************
CC	SEQRES LCGFAIAKSMSTFAIRETLRYAKAGKVVEETISSIRTVVSLNGLRYELER
CC	ATOM   LCGFAIAKSMSTFAIRETLRYAKAGKVVEETISSIRTVVSLNGLRYELER
CC	       **************************************************
CC	SEQRES YSTAVEEAKKAGVLKGLFLGISFGAMQASNFISFALAFYIGVGWVHDGSL
CC	ATOM   YSTAVEEAKKAGVLKGLFLGISFGAMQASNFISFALAFYIGVGWVHDGSL
CC	       **************************************************
CC	SEQRES NFGDMLTTFSSVMMGSMALGLAGPQLAVLGTAQGAASGIYEVLDRKPVID
CC	ATOM   NFGDMLTTFSSVMMGSMALGLAGPQLAVLGTAQGAASGIYEVLDRKPVID
CC	       **************************************************
CC	SEQRES SSSKAGRKDMKIKGDITVENVHFTYPSRPDVPILRGMNLRVNAGQTVALV
CC	ATOM   SSSKAGRKDMKIKGDITVENVHFTYPSRPDVPILRGMNLRVNAGQTVALV
CC	       **************************************************
CC	SEQRES GSSGCGKSTIISLLLRYYDVLKGKITIDGVDVRDINLEFLRKNVAVVSQE
CC	ATOM   GSSGCGKSTIISLLLRYYDVLKGKITIDGVDVRDINLEFLRKNVAVVSQE
CC	       **************************************************
CC	SEQRES PALFNCTIEENISLGKEGITREEMVAACKMANAEKFIKTLPNGYNTLVGD
CC	ATOM   PALFNCTIEENISLGKEGITREEMVAACKMANAEKFIKTLPNGYNTLVGD
CC	       **************************************************
CC	SEQRES RGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDAESEGIVQQALDKA
CC	ATOM   RGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDAESEGIVQQALDKA
CC	       **************************************************
CC	SEQRES AKGRTTIIIAHRLSTIRNADLIISCKNGQVVEVGDHRALMAQQGLYYDLV
CC	ATOM   AKGRTTIIIAHRLSTIRNADLIISCKNGQVVEVGDHRALMAQQGLYYDLV
CC	       **************************************************
CC	SEQRES TAQTFTDAVDSAAEGKFSRENSVARQTSEHEGLSRQASEMDDIMNRVRSS
CC	ATOM   TAQTFTDAVDSAAEG-----------------------------------
CC	       ***************                                   
CC	SEQRES TIGSITNGPVIDEKEERIGKDALSRLKQELEENNAQKTNLFEILYHARPH
CC	ATOM   ---------------ERIGKDALSRLKQELEENNAQKTNLFEILYHARPH
CC	                      ***********************************
CC	SEQRES ALSLFIGMSTATIGGFIYPTYSVFFTSFMNVFAGNPADFLSQGHFWALMF
CC	ATOM   ALSLFIGMSTATIGGFIYPTYSVFFTSFMNVFAGNPADFLSQGHFWALMF
CC	       **************************************************
CC	SEQRES LVLAAAQGICSFLMTFFMGIASESLTRDLRNKLFRNVLSQHIGFFDSPQN
CC	ATOM   LVLAAAQGICSFLMTFFMGIASESLTRDLRNKLFRNVLSQHIGFFDSPQN
CC	       **************************************************
CC	SEQRES ASGKISTRLATDVPNLRTAIDFRFSTVITTLVSMVAGIGLAFFYGWQMAL
CC	ATOM   ASGKISTRLATDVPNLRTAIDFRFSTVITTLVSMVAGIGLAFFYGWQMAL
CC	       **************************************************
CC	SEQRES LIIAILPIVAFGQYLRGRRFTGKNVKSASEFADSGKIAIEAIENVRTVQA
CC	ATOM   LIIAILPIVAFGQYLRGRRFTGKNVKSASEFADSGKIAIEAIENVRTVQA
CC	       **************************************************
CC	SEQRES LAREDTFYENFCEKLDIPHKEAIKEAFIQGLSYGCASSVLYLLNTCAYRM
CC	ATOM   LAREDTFYENFCEKLDIPHKEAIKEAFIQGLSYGCASSVLYLLNTCAYRM
CC	       **************************************************
CC	SEQRES GLALIITDPPTMQPMRVLRVMYAITISTSTLGFATSYFPEYAKATFAGGI
CC	ATOM   GLALIITDPPTMQPMRVLRVMYAITISTSTLGFATSYFPEYAKATFAGGI
CC	       **************************************************
CC	SEQRES IFGMLRKISKIDSLSLAGEKKKLYGKVIFKNVRFAYPERPEIEILKGLSF
CC	ATOM   IFGMLRKISKIDSLSLAGEKKKLYGKVIFKNVRFAYPERPEIEILKGLSF
CC	       **************************************************
CC	SEQRES SVEPGQTLALVGPSGCGKSTVVALLERFYDTLGGEIFIDGSEIKTLNPEH
CC	ATOM   SVEPGQTLALVGPSGCGKSTVVALLERFYDTLGGEIFIDGSEIKTLNPEH
CC	       **************************************************
CC	SEQRES TRSQIAIVSQEPTLFDCSIAENIIYGLDPSSVTMAQVEEAARLANIHNFI
CC	ATOM   TRSQIAIVSQEPTLFDCSIAENIIYGLDPSSVTMAQVEEAARLANIHNFI
CC	       **************************************************
CC	SEQRES AELPEGFETRVGDRGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDT
CC	ATOM   AELPEGFETRVGDRGTQLSGGQKQRIAIARALVRNPKILLLDEATSALDT
CC	       **************************************************
CC	SEQRES ESEKVVQEALDRAREGRTCIVIAHRLNTVMNADCIAVVSNGTIIEKGTHT
CC	ATOM   ESEKVVQEALDRAREGRTCIVIAHRLNTVMNADCIAVVSNGTIIEKGTHT
CC	       **************************************************
CC	SEQRES QLMSEKGAYYKLTQKQMTEKK
CC	ATOM   QLMSEK---------------
CC	       ******               
SQ	SEQUENCE	1321 AA;      MW;         CN;
	MLRNGSLRQS LRTLDSFSLA PEDVLKTAIK TVEDYEGDNI DSNGEIKITR DAKEEVVNKV
	SIPQLYRYTT TLEKLLLFIG TLVAVITGAG LPLMSILQGK VSQAFINEQI VINNNGSTFL
	PTGQNYTKTD FEHDVMNVVW SYAAMTVGMW AAGQITVTCY LYVAEQMNNR LRREFVKSIL
	RQEISWFDTN HSGTLATKLF DNLERVKEGT GDKIGMAFQY LSQFITGFIV AFTHSWQLTL
	VMLAVTPIQA LCGFAIAKSM STFAIRETLR YAKAGKVVEE TISSIRTVVS LNGLRYELER
	YSTAVEEAKK AGVLKGLFLG ISFGAMQASN FISFALAFYI GVGWVHDGSL NFGDMLTTFS
	SVMMGSMALG LAGPQLAVLG TAQGAASGIY EVLDRKPVID SSSKAGRKDM KIKGDITVEN
	VHFTYPSRPD VPILRGMNLR VNAGQTVALV GSSGCGKSTI ISLLLRYYDV LKGKITIDGV
	DVRDINLEFL RKNVAVVSQE PALFNCTIEE NISLGKEGIT REEMVAACKM ANAEKFIKTL
	PNGYNTLVGD RGTQLSGGQK QRIAIARALV RNPKILLLDE ATSALDAESE GIVQQALDKA
	AKGRTTIIIA HRLSTIRNAD LIISCKNGQV VEVGDHRALM AQQGLYYDLV TAQTFTDAVD
	SAAEGKFSRE NSVARQTSEH EGLSRQASEM DDIMNRVRSS TIGSITNGPV IDEKEERIGK
	DALSRLKQEL EENNAQKTNL FEILYHARPH ALSLFIGMST ATIGGFIYPT YSVFFTSFMN
	VFAGNPADFL SQGHFWALMF LVLAAAQGIC SFLMTFFMGI ASESLTRDLR NKLFRNVLSQ
	HIGFFDSPQN ASGKISTRLA TDVPNLRTAI DFRFSTVITT LVSMVAGIGL AFFYGWQMAL
	LIIAILPIVA FGQYLRGRRF TGKNVKSASE FADSGKIAIE AIENVRTVQA LAREDTFYEN
	FCEKLDIPHK EAIKEAFIQG LSYGCASSVL YLLNTCAYRM GLALIITDPP TMQPMRVLRV
	MYAITISTST LGFATSYFPE YAKATFAGGI IFGMLRKISK IDSLSLAGEK KKLYGKVIFK
	NVRFAYPERP EIEILKGLSF SVEPGQTLAL VGPSGCGKST VVALLERFYD TLGGEIFIDG
	SEIKTLNPEH TRSQIAIVSQ EPTLFDCSIA ENIIYGLDPS SVTMAQVEEA ARLANIHNFI
	AELPEGFETR VGDRGTQLSG GQKQRIAIAR ALVRNPKILL LDEATSALDT ESEKVVQEAL
	DRAREGRTCI VIAHRLNTVM NADCIAVVSN GTIIEKGTHT QLMSEKGAYY KLTQKQMTEK
	K
//