PDB ID: 4E5W
Hetero Atom Contents
The number of atoms exceeds 100,000. So, it can not be displayed here.
Select unit:
Select hetatm:
Select chain: Sequence
Data format:
Color scheme of protein:
Code | Name | Style | Show | Link | |
---|---|---|---|---|---|
0NT | [4-(imidazo[4,5-D]pyrrolo[2,3-B]pyridin-1(6h)-yl)piperidin-1-yl][(2s)-1-(propan-2-yl)pyrrolidin-2-yl]methanone | PoSSuM | |||
PEG | Di(hydroxyethyl)ether | PoSSuM |
Code | Name | Show |
---|---|---|
PTR | O-phosphotyrosine |
Code | Name | Emphasize |
---|
Code | Name | Show |
---|
Download interaction data: 4E5W
Structure summary
Code : | 4E5W PDBj RCSB PDB PDBe | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Header : | TRANSFERASE/TRANSFERASE INHIBITOR | ||||||||||||
Title : | JAK1 kinase (JH1 domain) in complex with compound 26 | ||||||||||||
Release Data : | 2012-05-30 | ||||||||||||
Compound : |
|
||||||||||||
Source : |
|
||||||||||||
Authors : | Murray, J.M. | ||||||||||||
Keywords : | JAK1, kinase domain, kinase, TRANSFERASE-TRANSFERASE INHIBITOR complex | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.860 Å ) | ||||||||||||
Citation : |
Identification of Imidazo-Pyrrolopyridines as Novel and Potent JAK1 Inhibitors.
Kulagowski, J.J.,Blair, W.,Bull, R.J.
et al.
PubMed: 22591402 |
Reaction
Chain : | A, B | ||||||||
---|---|---|---|---|---|---|---|---|---|
UniProt : | P23458 (JAK1_HUMAN) | ||||||||
|