Het-PDB Navi2 (PDB: 3K4S)

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Ligands
Code	Name	Link
0MO	(4r)-4-(3-butoxy-4-methoxybenzyl)imidazolidin-2-one	PoSSuM
MG	Magnesium ion	PoSSuM
ZN	Zinc ion	PoSSuM

Non-standard Residues
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Download interaction data: 3K4S

Code :

3K4S PDBj RCSB PDB PDBe

Header :

HYDROLASE

Title :

The structure of the catalytic domain of human PDE4d with 4-(3-Butoxy-4-methoxyphenyl)methyl-2-imidazolidone

Release Data :

2009-10-20

Compound :

mol_id	molecule	chains	synonym
1	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	A	DPDE3, PDE43
	ec: 3.1.4.17 fragment: catalytic domain, residues 388-654

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Escherichia coli (taxid:562)
	gene: PDE4D, DPDE3 expression_system_strain: Arctic Express RP (DE3) expression_system_vector_type: Plasmid expression_system_plasmid: pET28a

Authors :

Crawley, L., Cheng, R.K.Y., Wood, M., Barker, J., Felicetti, B., Whittaker, M.

Keywords :

nucleotide binding, phosphodiesterase, Alternative splicing, cAMP, Cytoplasm, Cytoskeleton, Hydrolase, Membrane, Metal-binding, Phosphoprotein

Exp. method :

X-RAY DIFFRACTION ( 2.05 Å )

Citation :

The structure of the catalytic domain of human PDE4d with 4-(3-Butoxy-4-methoxyphenyl)methyl-2-imidazolidone

Crawley, L.,Cheng, R.K.Y.,Wood, M. et al.
To be Published

Chain :

UniProt :

Q08499 (PDE4D_HUMAN)

PDB ID: 3K4S