ID	3K4SA	STANDARD;	PRT;	349	AA.
DT	CONVERTED FROM PDB (SEQRES) 3K4S
DE	cAMP-specific 3',5'-cyclic phosphodiesterase 4D
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.050
CC	R-Factor	0.211
FT	#HET	95	 159 	TYR	A	2	414 	0MO	A	S	3
FT	#HET	100	 164 	HIS	A	1	1 	ZN	A	S	3
FT	#HET	136	 200 	HIS	A	1	1 	ZN	A	S	3
FT	#HET	137	 201 	ASP	A	1	1 	ZN	A	S	3
FT	#HET	137	 201 	ASP	A	3	415 	MG	A	S	3
FT	#HET	209	 273 	MET	A	2	414 	0MO	A	S	1
FT	#HET	254	 318 	ASP	A	1	1 	ZN	A	S	3
FT	#HET	257	 321 	ASN	A	2	414 	0MO	A	S	3
FT	#HET	265	 329 	TYR	A	2	414 	0MO	A	S	1
FT	#HET	269	 333 	THR	A	2	414 	0MO	A	A	3
FT	#HET	272	 336 	ILE	A	2	414 	0MO	A	S	3
FT	#HET	273	 337 	MET	A	2	414 	0MO	A	S	2
FT	#HET	276	 340 	PHE	A	2	414 	0MO	A	S	3
FT	#HET	293	 357 	MET	A	2	414 	0MO	A	S	1
FT	#HET	305	 369 	GLN	A	2	414 	0MO	A	S	8
FT	#HET	308	 372 	PHE	A	2	414 	0MO	A	S	17
FT	DISORDER	1	19
FT	DISORDER	349	349
CC	SEQUENCE	329 AA (ATOM);
CC	HMTEQEDVLA KELEDVNKWG LHVFRIAELS GNRPLTVIMH TIFQERDLLK TFKIPVDTLI
CC	TYLMTLEDHY HADVAYHNNI HAADVVQSTH VLLSTPALEA VFTDLEILAA IFASAIHDVD
CC	HPGVSNQFLI NTNSELALMY NDSSVLENHH LAVGFKLLQE ENCDIFQNLT KKQRQSLRKM
CC	VIDIVLATDM SKHMNLLADL KTMVETKKVT SSGVLLLDNY SDRIQVLQNM VHCADLSNPT
CC	KPLQLYRQWT DRIMEEFFRQ GDRERERGME ISPMCDKHNA SVEKSQVGFI DYIVHPLWET
CC	WADLVHPDAQ DILDTLEDNR EWYQSTIPQ
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MGSSHHHHHHSSGLVPRGSHMTEQEDVLAKELEDVNKWGLHVFRIAELSG
CC	ATOM   -------------------HMTEQEDVLAKELEDVNKWGLHVFRIAELSG
CC	                          *******************************
CC	SEQRES NRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIH
CC	ATOM   NRPLTVIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIH
CC	       **************************************************
CC	SEQRES AADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLIN
CC	ATOM   AADVVQSTHVLLSTPALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLIN
CC	       **************************************************
CC	SEQRES TNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMV
CC	ATOM   TNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQSLRKMV
CC	       **************************************************
CC	SEQRES IDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMV
CC	ATOM   IDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMV
CC	       **************************************************
CC	SEQRES HCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNAS
CC	ATOM   HCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNAS
CC	       **************************************************
CC	SEQRES VEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQS
CC	ATOM   VEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQ-
CC	       ************************************************ 
SQ	SEQUENCE	349 AA;      MW;         CN;
	MGSSHHHHHH SSGLVPRGSH MTEQEDVLAK ELEDVNKWGL HVFRIAELSG NRPLTVIMHT
	IFQERDLLKT FKIPVDTLIT YLMTLEDHYH ADVAYHNNIH AADVVQSTHV LLSTPALEAV
	FTDLEILAAI FASAIHDVDH PGVSNQFLIN TNSELALMYN DSSVLENHHL AVGFKLLQEE
	NCDIFQNLTK KQRQSLRKMV IDIVLATDMS KHMNLLADLK TMVETKKVTS SGVLLLDNYS
	DRIQVLQNMV HCADLSNPTK PLQLYRQWTD RIMEEFFRQG DRERERGMEI SPMCDKHNAS
	VEKSQVGFID YIVHPLWETW ADLVHPDAQD ILDTLEDNRE WYQSTIPQS
//