Brand  (β version)

color scheme of protein:

hetatm:

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information
centroid:
interaction residue:

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Ligands
Code Name Link
0NX (5-phenyl-1,2-oxazol-3-yl)methanol
CD Cadmium ion
SO4 Sulfate ion
Code : 3VQ4
Header : TRANSFERASE/TRANSFERASE INHIBITOR
Title : Fragments bound to HIV-1 integrase
Release Data : 2013-01-30
Compound :
mol_id molecule chains
1 POL polyprotein A,B
fragment: Integrase CATALYTIC CORE DOMAIN, UNP residues 770-927
mutation: C56S W131D, F139D, F185H
Source :
mol_id organism_scientific expression_system
1 Human immunodeficiency virus 1  (taxid:11676) Escherichia coli  (taxid:562)
strain: NL43
gene: pol
expression_system_strain: BL21(DE3)
expression_system_vector_type: Plasmid
expression_system_plasmid: PeT23b+
Authors : Wielens, J., Chalmers, D.K., Parker, M.W., Scanlon, M.J.
Keywords : RNaseH, DNA binding, DNA cleavage, DNA integration, TRANSFERASE-TRANSFERASE INHIBITOR complex
Exp. method : X-RAY DIFFRACTION ( 1.90 Å )
Citation :

Parallel screening of low molecular weight fragment libraries: do differences in methodology affect hit identification?

Wielens, J.,Headey, S.J.,Rhodes, D.I.  et al.
(2013)  J Biomol Screen  18 : 147 - 159

PubMed: 23139382
DOI: 10.1177/1087057112465979

Chain : A, B
UniProt : Q72498 (No found in current UniProtKB/SwissProt)
Reaction : -