PDB ID: 3QG2
Hetero Atom Contents
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Code | Name | Style | Show | Link | |
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CP6 | 5-(4-chloro-phenyl)-6-ethyl-pyrimidine-2,4-diamine | PoSSuM | |||
NDP | Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate | PoSSuM | |||
UMP | 2'-deoxyuridine 5'-monophosphate | PoSSuM |
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Download interaction data: 3QG2
Structure summary
Code : | 3QG2 PDBj RCSB PDB PDBe | ||||||||||||
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Header : | OXIDOREDUCTASE, TRANSFERASE/INHIBITOR | ||||||||||||
Title : | Plasmodium falciparum DHFR-TS qradruple mutant (N51I+C59R+S108N+I164L, V1/S) pyrimethamine complex | ||||||||||||
Release Data : | 2011-06-29 | ||||||||||||
Compound : |
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Authors : | Vanichtanankul, J., Yuvaniyama, J., Taweechai, S., Chitnumsub, P., Kamchonwongpaisan, S., Yuthavong, Y. | ||||||||||||
Keywords : | pyrimethamine, antifolate resistance, Plasmodium falciparum, dihydrofolate reductase, OXIDOREDUCTASE, TRANSFERASE, TRANSFERASE-INHIBITOR complex | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.3000 Å ) | ||||||||||||
Citation : |
Trypanosomal dihydrofolate reductase reveals natural antifolate resistance
Vanichtanankul, J.,Taweechai, S.,Yuvaniyama, J.
et al.
PubMed: 21650210 |
Reaction
Chain : | A, B | ||||||||||||
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UniProt : | D9N170 (D9N170_PLAFA) | ||||||||||||
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