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CP6

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Hetero-Atom Name 5-(4-chloro-phenyl)-6-ethyl-pyrimidine-2,4-diamine
Synonym pyrimethamine
Code CP6
Formula C12 H13 CL N4
Similar Hetero-Atom 3 Hetero-Atoms
Links DrugBank   DB00205  
KEGG Drug   D00488  
KEGG Compound   C07391  
PDB Ligand   PDBj   RCSB PDB   PDBe
Code 1J3J
TitleDouble mutant (C59R+S108N) Plasmodium falciparum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS) complexed with pyrimethamine, NADPH, and dUMP
SoucePlasmodium falciparum (malaria parasite P. falciparum)
Code 2BL9
TitleX-ray crystal structure of Plasmodium vivax dihydrofolate reductase in complex with pyrimethamine and its derivative
SoucePLASMODIUM VIVAX
Code 2BLA
TitleSP21 double mutant P. vivax Dihydrofolate reductase in complex with pyrimethamine
SoucePLASMODIUM VIVAX
Code 3LMY
TitleThe Crystal Structure of beta-hexosaminidase B in complex with Pyrimethamine
SouceHomo sapiens (human)
Code 3QFX
TitleTrypanosoma brucei dihydrofolate reductase pyrimethamine complex
SouceTrypanosoma brucei rhodesiense
Code 3QG2
TitlePlasmodium falciparum DHFR-TS qradruple mutant (N51I+C59R+S108N+I164L, V1/S) pyrimethamine complex
SoucePlasmodium falciparum
Code 3QGT
TitleCrystal structure of Wild-type PfDHFR-TS COMPLEXED WITH NADPH, dUMP AND PYRIMETHAMINE
SoucePlasmodium falciparum
Code 3UM5
TitleDouble mutant (A16V+S108T) Plasmodium falciparum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS-T9/94) complexed with pyrimethamine, NADPH, and dUMP
SoucePlasmodium falciparum
Code 4KM0
TitleCrystal structure of dihydrofolate reductase from Mycobacterium tuberculosis in complex with pyrimethamine
SouceMycobacterium tuberculosis
Code 6AOG
TitleCrystal structure of Toxoplasma gondii TS-DHFR complexed with NADPH, dUMP, PDDF, and 5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine (pyrimethamine)
SouceToxoplasma gondii