Het-PDB Navi2 (PDB: 3MDA)

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Data format:

Color scheme of protein:

Ligands
Code	Name	Link
MG	Magnesium ion	PoSSuM
NA	Sodium ion	PoSSuM
PPV	Pyrophosphate	PoSSuM

Non-standard Residues
Code	Name	Show
CAR	Cytosine arabinose-5'-phosphate

Glycosylation
Code	Name	Emphasize

Modification
Code	Name	Show

Download interaction data: 3MDA

Code :

3MDA PDBj RCSB PDB PDBe

Header :

Lyase,Transferase/DNA

Title :

DNA polymerase lambda in complex with araC

Release Data :

2010-04-28

Compound :

mol_id	molecule	chains	synonym
1	DNA polymerase lambda	A	Pol Lambda, DNA polymerase kappa, DNA polymerase beta-2, Pol beta2
	ec: 2.7.7.7, 4.2.99.-

mol_id	molecule	chains
2	DNA (5'-D(CPGPGPCPGPGPTPAPCPTP*G)-3')	T

mol_id	molecule	chains
3	DNA (5'-D(CPAPGPTPAPCP*(CAR))-3')	P

mol_id	molecule	chains
4	DNA (5'-D(PGPCPCPG)-3')	D

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Escherichia coli (taxid:562)
	gene: POLL expression_system_strain: BL21(DE3)RIL expression_system_vector_type: plasmid expression_system_plasmid: pET22

mol_id	organism_scientific
2
	synthetic: yes other_details: The DNA fragment is chemically synthesized.

mol_id	organism_scientific
3
	synthetic: yes other_details: The DNA fragment is chemically synthesized.

mol_id	organism_scientific
4
	synthetic: yes other_details: The DNA fragment is chemically synthesized.

Authors :

Garcia-Diaz, M., Murray, M., Kunkel, T., Chou, K.M.

Keywords :

protein-DNA complex, Lyase, Transferase-DNA complex

Exp. method :

X-RAY DIFFRACTION ( 2.031 Å )

Citation :

Interaction between DNA Polymerase lambda and anticancer nucleoside analogs.

Garcia-Diaz, M.,Murray, M.S.,Kunkel, T.A. et al.
(2010) J.Biol.Chem. 285 : 16874 - 16879

PDB ID: 3MDA