PDB ID: 2H2Q
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Structure summary
Code : | 2H2Q PDBj RCSB PDB PDBe | ||||||||||||
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Header : | OXIDOREDUCTASE, TRANSFERASE | ||||||||||||
Title : | Crystal structure of Trypanosoma cruzi Dihydrofolate Reductase-Thymidylate synthase | ||||||||||||
Release Data : | 2008-04-08 | ||||||||||||
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Authors : | Senkovich, O., Schormann, N., Chattopadhyay, D. | ||||||||||||
Keywords : | Bifunctional enzyme in complex with NADP and dUMP, OXIDOREDUCTASE, TRANSFERASE | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.40 Å ) | ||||||||||||
Citation : |
Structure-based approach to pharmacophore identification, in silico screening, and three-dimensional quantitative structure-activity relationship studies for inhibitors of Trypanosoma cruzi dihydrofolate reductase function.
Schormann, N.,Senkovich, O.,Walker, K.
et al.
PubMed: 18536013 |
Reaction
Chain : | A, B | ||||||||||||
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UniProt : | Q27793 (DRTS_TRYCR) | ||||||||||||
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