Het-PDB Navi2 (PDB: 1E2P)

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Ligands
Code	Name		Style	Show	Link
CCV	6-[3-hydroxy-2-(hydroxymethyl)propyl]-5-methyl-2,4(1h,3h)-pyrimidinedione				PoSSuM
SO4	Sulfate ion				PoSSuM

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Download interaction data: 1E2P

Code :

1E2P PDBj RCSB PDB PDBe

Header :

TRANSFERASE

Title :

Thymidine kinase, DHBT

Release Data :

2001-04-26

Compound :

mol_id	molecule	chains
1	THYMIDINE KINASE	A,B
	ec: 2.7.1.21

Source :

mol_id	organism_scientific	expression_system
1	HERPES SIMPLEX VIRUS TYPE 1 (taxid:10298)	ESCHERICHIA COLI (taxid:562)
	strain: 17

Authors :

Schulz, G.E., Kessler, U.

Keywords :

TRANSFERASE, KINASE, DNA SYNTHESIS, ATP-BINDING

Exp. method :

X-RAY DIFFRACTION ( 2.5 Å )

Citation :

The Effect of Substrate Binding on the Conformation and Structural Stability of Herpes Simplex Virus Type 1 Thymidine Kinase

Wurth, C.,Kessler, U.,Vogt, J. et al.
(2001) Protein Sci. 10 : 63

The Three-Dimensional Structure of Thymidine Kinase from Herpes Simplex Virus Type 1

Wild, K.,Bohner, T.,Aubry, A. et al.
(1995) FEBS Lett. 368 : 289

Crystal Structures of the Thymidine Kinase from Herpes Simplex Virus Type-1 in Complex with Deoxythymidine and Ganciclovir

Brown, D.G.,Visse, R.,Sandhu, G. et al.
(1995) Nat.Struct.Biol. 2 : 876

PDB ID: 1E2P