Brand  (β version)

PDB ID: 1NJI

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Ligands
Code Name Style Show Link
CD Cadmium ion PoSSuM
CL Chloride ion PoSSuM
CLM Chloramphenicol PoSSuM
K Potassium ion PoSSuM
MG Magnesium ion PoSSuM
NA Sodium ion PoSSuM
Non-standard Residues
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Glycosylation
Code Name Emphasize
Modification
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Structure summary

Code : 1NJI   PDBj   RCSB PDB   PDBe
Header : RIBOSOME
Title : Structure of chloramphenicol bound to the 50S ribosomal subunit
Release Data : 2003-07-22
Compound :
mol_id molecule chains
1 23S ribosomal RNA A
mol_id molecule chains
2 5S ribosomal RNA B
mol_id molecule chains synonym
3 50S ribosomal protein L2P C Hmal2, HL4
mol_id molecule chains synonym
4 50S ribosomal protein L3P D Hmal3, HL1
mutation: R310P, 311F insertion
mol_id molecule chains synonym
5 50S ribosomal protein L4E E Hmal4, HL6
mol_id molecule chains synonym
6 50S ribosomal protein L5P F Hmal5, HL13
mol_id molecule chains synonym
7 50S ribosomal protein L6P G Hmal6, HL10
mol_id molecule chains synonym
8 50S ribosomal protein L7Ae H HS6
mol_id molecule chains synonym
9 Acidic ribosomal protein P0 homolog I L10E, HMaL10
mol_id molecule chains
10 50S ribosomal protein L10e J
mol_id molecule chains synonym
11 50S ribosomal protein L13P K Hmal13
mol_id molecule chains synonym
12 50S ribosomal protein L14P L Hmal14, HL27
mol_id molecule chains synonym
13 50S ribosomal protein L15P M Hmal15, HL9
mol_id molecule chains
14 50S ribosomal protein L15E N
mol_id molecule chains synonym
15 50S ribosomal protein L18P O Hmal18, HL12
mol_id molecule chains synonym
16 50S ribosomal protein L18E P HL29, L19
mol_id molecule chains synonym
17 50S ribosomal protein L19E Q Hmal19, HL24
mol_id molecule chains synonym
18 50S ribosomal protein L21e R HL31
mol_id molecule chains synonym
19 50S ribosomal protein L22P S Hmal22, HL23
mol_id molecule chains synonym
20 50S ribosomal protein L23P T Hmal23, HL25, L21
mol_id molecule chains synonym
21 50S ribosomal protein L24P U Hmal24, HL16, HL15
mol_id molecule chains synonym
22 50S ribosomal protein L24E V HL21/HL22
mol_id molecule chains synonym
23 50S ribosomal protein L29P W Hmal29, HL33
mol_id molecule chains synonym
24 50S ribosomal protein L30P X Hmal30, HL20, HL16
mol_id molecule chains synonym
25 50S ribosomal protein L31E Y L34, HL30
mol_id molecule chains synonym
26 50S ribosomal protein L32E Z HL5
mol_id molecule chains
27 50S ribosomal protein L37AE 1
mol_id molecule chains synonym
28 50S ribosomal protein L37e 2 L35e
mol_id molecule chains synonym
29 50S ribosomal protein L39e 3 HL39e, HL46e
mol_id molecule chains synonym
30 50S ribosomal protein L44E 4 LA, HLA
Source :
mol_id organism_scientific
1 Haloarcula marismortui  (taxid:2238)
other_details: cultured cells
mol_id organism_scientific
2 Haloarcula marismortui  (taxid:2238)
other_details: cultured cells
mol_id organism_scientific
3 Haloarcula marismortui  (taxid:2238)
other_details: cultured cells
mol_id organism_scientific
4 Haloarcula marismortui  (taxid:2238)
other_details: cultured cells
mol_id organism_scientific
5 Haloarcula marismortui  (taxid:2238)
other_details: cultured cells
mol_id organism_scientific
6 Haloarcula marismortui  (taxid:2238)
other_details: cultured cells
mol_id organism_scientific
7 Haloarcula marismortui  (taxid:2238)
other_details: cultured cells
mol_id organism_scientific
8 Haloarcula marismortui  (taxid:2238)
other_details: cultured cells
mol_id organism_scientific
9 Haloarcula marismortui  (taxid:2238)
other_details: cultured cells
mol_id organism_scientific
10 Haloarcula marismortui  (taxid:2238)
other_details: cultured cells
mol_id organism_scientific
11 Haloarcula marismortui  (taxid:2238)
other_details: cultured cells
mol_id organism_scientific
12 Haloarcula marismortui  (taxid:2238)
other_details: cultured cells
mol_id organism_scientific
13 Haloarcula marismortui  (taxid:2238)
other_details: cultured cells
mol_id organism_scientific
14 Haloarcula marismortui  (taxid:2238)
other_details: cultured cells
mol_id organism_scientific
15 Haloarcula marismortui  (taxid:2238)
other_details: cultured cells
mol_id organism_scientific
16 Haloarcula marismortui  (taxid:2238)
other_details: cultured cells
mol_id organism_scientific
17 Haloarcula marismortui  (taxid:2238)
other_details: cultured cells
mol_id organism_scientific
18 Haloarcula marismortui  (taxid:2238)
other_details: cultured cells
mol_id organism_scientific
19 Haloarcula marismortui  (taxid:2238)
other_details: cultured cells
mol_id organism_scientific
20 Haloarcula marismortui  (taxid:2238)
other_details: cultured cells
mol_id organism_scientific
21 Haloarcula marismortui  (taxid:2238)
other_details: cultured cells
mol_id organism_scientific
22 Haloarcula marismortui  (taxid:2238)
other_details: cultured cells
mol_id organism_scientific
23 Haloarcula marismortui  (taxid:2238)
other_details: cultured cells
mol_id organism_scientific
24 Haloarcula marismortui  (taxid:2238)
other_details: cultured cells
mol_id organism_scientific
25 Haloarcula marismortui  (taxid:2238)
other_details: cultured cells
mol_id organism_scientific
26 Haloarcula marismortui  (taxid:2238)
other_details: cultured cells
mol_id organism_scientific
27 Haloarcula marismortui  (taxid:2238)
other_details: cultured cells
mol_id organism_scientific
28 Haloarcula marismortui  (taxid:2238)
other_details: cultured cells
mol_id organism_scientific
29 Haloarcula marismortui  (taxid:2238)
other_details: cultured cells
mol_id organism_scientific
30 Haloarcula marismortui  (taxid:2238)
other_details: cultured cells
Authors : Hansen, J.L., Moore, P.B., Steitz, T.A.
Keywords : 50S, antibiotic, chloramphenicol, LSU, RIBOSOME
Exp. method : X-RAY DIFFRACTION ( 3.00 Å )
Citation :

Structures of Five Antibiotics Bound at the Peptidyl Transferase Center of the Large Ribosomal Subunit

Hansen, J.,Moore, P.B.,Steitz, T.A.
(2003)  J.Mol.Biol.  330 : 1061 - 1075

PubMed: 12860128
DOI: 10.1016/S0022-2836(03)00668-5

The complete atomic structure of the large ribosomal subunit at 2.4 A resolution

Ban, N.,Nissen, P.,Hansen, J.  et al.
(2000)  Science  289 : 905 - 920

DOI: 10.1126/science.289.5481.905

The structural basis of ribosome activity in peptide bond synthesis

Nissen, P.,Hansen, J.,Ban, N.  et al.
(2000)  Science  289 : 920 - 930

DOI: 10.1126/science.289.5481.920

Reaction

Chain : C
UniProt : P20276 (RL2_HALMA)
Reaction : -
Chain : D
UniProt : P20279 (RL3_HALMA)
Reaction : -
Chain : E
UniProt : P12735 (RL4_HALMA)
Reaction : -
Chain : F
UniProt : P14124 (RL5_HALMA)
Reaction : -
Chain : G
UniProt : P14135 (RL6_HALMA)
Reaction : -
Chain : H
UniProt : P12743 (RL7A_HALMA)
Reaction : -
Chain : I
UniProt : P15825 (RL10_HALMA)
Reaction : -
Chain : K
UniProt : P29198 (RL13_HALMA)
Reaction : -
Chain : L
UniProt : P22450 (RL14_HALMA)
Reaction : -
Chain : M
UniProt : P12737 (RL15_HALMA)
Reaction : -
Chain : O
UniProt : P14123 (RL18_HALMA)
Reaction : -
Chain : P
UniProt : P12733 (RL18E_HALMA)
Reaction : -
Chain : Q
UniProt : P14119 (RL19E_HALMA)
Reaction : -
Chain : R
UniProt : P12734 (RL21_HALMA)
Reaction : -
Chain : S
UniProt : P10970 (RL22_HALMA)
Reaction : -
Chain : T
UniProt : P12732 (RL23_HALMA)
Reaction : -
Chain : U
UniProt : P10972 (RL24_HALMA)
Reaction : -
Chain : V
UniProt : P14116 (RL24E_HALMA)
Reaction : -
Chain : W
UniProt : P10971 (RL29_HALMA)
Reaction : -
Chain : X
UniProt : P14121 (RL30_HALMA)
Reaction : -
Chain : Y
UniProt : P18138 (RL31_HALMA)
Reaction : -
Chain : Z
UniProt : P12736 (RL32_HALMA)
Reaction : -
Chain : 2
UniProt : P32410 (RL37_HALMA)
Reaction : -
Chain : 3
UniProt : P22452 (RL39_HALMA)
Reaction : -
Chain : 4
UniProt : P32411 (RL44E_HALMA)
Reaction : -