Brand  (β version)

PDB ID: 1MPA

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Ligands
Code Name Style Show Link
CD Cadmium ion PoSSuM
Non-standard Residues
Code Name Show
THC N-methylcarbonylthreonine
CYF 5-[2-(2-amino-2-carbamoyl-ethylsulfanyl)-acetylamino]-2-(3,6-dihydroxy-9,9a-dihydro-3h-xanthen-9-yl)-benzoic acid
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Structure summary

Code : 1MPA   PDBj   RCSB PDB   PDBe
Header : COMPLEX (IMMUNOGLOBULIN/PEPTIDE)
Title : BACTERICIDAL ANTIBODY AGAINST NEISSERIA MENINGITIDIS
Release Data : 1997-09-04
Compound :
mol_id molecule chains
1 MN12H2 IGG2A-KAPPA L
fragment: FAB FRAGMENT
mol_id molecule chains
2 MN12H2 IGG2A-KAPPA H
fragment: FAB FRAGMENT
mol_id molecule chains synonym
3 PORA P1.16 PEPTIDE FLUORESCEIN CONJUGATE P P1.16, AC-TKDTNNNLC(FLUORESCEIN)-NH2
fragment: APEX OF EXTRACELLULAR LOOP 4 (VR2) OF PORA, RESIDUES 180 - 187
Source :
mol_id organism_scientific organism_common expression_system
1 Mus musculus  (taxid:10090) House mouse Mus musculus  (taxid:10090)
strain: BALB/C
cell: B-LYMPHOCYTE HYBRIDOMA
expression_system_common: House mouse
expression_system_cell_line: MN12H2 MURINE-MURINE HYBRIDOMA CELL LINE
mol_id organism_scientific organism_common expression_system
2 Mus musculus  (taxid:10090) House mouse Mus musculus  (taxid:10090)
strain: BALB/C
cell: B-LYMPHOCYTE HYBRIDOMA
expression_system_common: House mouse
expression_system_cell_line: MN12H2 MURINE-MURINE HYBRIDOMA CELL LINE
mol_id organism_scientific
3
Authors : Van Den Elsen, J.M.H., Herron, J.N., Kroon, J., Gros, P.
Keywords : MURINE IMMUNOGLOBULIN IGG2A KAPPA, BACTERICIDAL ANTIBODY, EPITOPE P1.16 OF PORA FROM NEISSERIA MENINGITIDIS, COMPLEX (IMMUNOGLOBULIN-PEPTIDE), COMPLEX (IMMUNOGLOBULIN-PEPTIDE) complex
Exp. method : X-RAY DIFFRACTION ( 2.6 Å )
Citation :

Bactericidal antibody recognition of a PorA epitope of Neisseria meningitidis: crystal structure of a Fab fragment in complex with a fluorescein-conjugated peptide.

van den Elsen, J.M.,Herron, J.N.,Hoogerhout, P.  et al.
(1997)  Proteins  29 : 113 - 125

PubMed: 9294871
DOI: 10.1002/(SICI)1097-0134(199709)29:1<113::AID-PROT9>3.3.CO;2-U