Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain:

Ligands
Code Name Link
ADP Adenosine-5'-diphosphate
CL Chloride ion
EPE 4-(2-hydroxyethyl)-1-piperazine ethanesulfonic acid
MG Magnesium ion
PT Platinum (II) ion
Code : 1L4U   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : CRYSTAL STRUCTURE OF SHIKIMATE KINASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH MGADP AND PT(II) AT 1.8 ANGSTROM RESOLUTION
Release Data : 2002-06-12
Compound :
mol_id molecule chains synonym
1 SHIKIMATE KINASE A SK
ec: 2.7.1.71
Source :
mol_id organism_scientific expression_system
1 Mycobacterium tuberculosis  (taxid:1773) Escherichia coli BL21(DE3)  (taxid:469008)
gene: AROK
expression_system_strain: BL21(DE3)
expression_system_vector_type: PLASMID
expression_system_plasmid: PET-17B
Authors : Gu, Y., Reshetnikova, L., Li, Y., Wu, Y., Yan, H., Singh, S., Ji, X.
Keywords : SHIKIMATE PATHWAY, SHIKIMATE KINASE, PHORSPHORYL TRANSFER, DRUG DESIGN, TRANSFERASE
Exp. method : X-RAY DIFFRACTION ( 1.80 Å )
Citation :

Crystal structure of shikimate kinase from Mycobacterium tuberculosis reveals the dynamic role of the LID domain in catalysis.

Gu, Y.,Reshetnikova, L.,Li, Y.  et al.
(2002)  J.Mol.Biol.  319 : 779 - 789

PubMed: 12054870
DOI: 10.1016/S0022-2836(02)00339-X

Chain : A
UniProt : P0A4Z2 (multiple entry names are found)
Reaction : -