Brand  (β version)

PDB ID: 1K8A

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Ligands
Code Name Style Show Link
CAI Carbomycin a PoSSuM
CD Cadmium ion PoSSuM
CL Chloride ion PoSSuM
K Potassium ion PoSSuM
MG Magnesium ion PoSSuM
NA Sodium ion PoSSuM
Non-standard Residues
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Glycosylation
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Structure summary

Code : 1K8A   PDBj   RCSB PDB   PDBe
Header : RIBOSOME
Title : Co-crystal structure of Carbomycin A bound to the 50S ribosomal subunit of Haloarcula marismortui
Release Data : 2002-07-19
Compound :
mol_id molecule chains
1 23S RRNA A
mol_id molecule chains
2 5S RRNA B
mol_id molecule chains synonym
3 RIBOSOMAL PROTEIN L2 C 50S RIBOSOMAL PROTEIN L2P, HMAL2, HL4
mol_id molecule chains synonym
4 RIBOSOMAL PROTEIN L3 D 50S RIBOSOMAL PROTEIN L3P, HMAL3, HL1
mol_id molecule chains synonym
5 RIBOSOMAL PROTEIN L4 E 50S RIBOSOMAL PROTEIN L4E, HMAL4, HL6
mol_id molecule chains synonym
6 RIBOSOMAL PROTEIN L5 F 50S RIBOSOMAL PROTEIN L5P, HMAL5, HL13
mol_id molecule chains synonym
7 RIBOSOMAL PROTEIN L6 G 50S RIBOSOMAL PROTEIN L6P, HMAL6, HL10
mol_id molecule chains synonym
8 RIBOSOMAL PROTEIN L7AE H 50S RIBOSOMAL PROTEIN HS6
mol_id molecule chains synonym
9 RIBOSOMAL PROTEIN L10 I 50S RIBOSOMAL PROTEIN P0, HMAL10, L10E
mol_id molecule chains
10 RIBOSOMAL PROTEIN L10E J
mol_id molecule chains synonym
11 RIBOSOMAL PROTEIN L13 K 50S RIBOSOMAL PROTEIN L13P, HMAL13
mol_id molecule chains synonym
12 RIBOSOMAL PROTEIN L14 L 50S RIBOSOMAL PROTEIN L14P, HMAL14, HL27
mol_id molecule chains synonym
13 RIBOSOMAL PROTEIN L15 M 50S RIBOSOMAL PROTEIN L15P, HMAL15, HL9
mol_id molecule chains
14 RIBOSOMAL PROTEIN L15E N
mol_id molecule chains synonym
15 RIBOSOMAL PROTEIN L18 O 50S RIBOSOMAL PROTEIN L18P, HMAL18, HL12
mol_id molecule chains synonym
16 RIBOSOMAL PROTEIN L18E P 50S RIBOSOMAL PROTEIN L18E, HL29, L19
mol_id molecule chains synonym
17 RIBOSOMAL PROTEIN L19E Q 50S RIBOSOMAL PROTEIN L19E, HMAL19, HL24
mol_id molecule chains synonym
18 RIBOSOMAL PROTEIN L21E R 50S RIBOSOMAL PROTEIN L21E, HL31
mol_id molecule chains synonym
19 RIBOSOMAL PROTEIN L22 S 50S RIBOSOMAL PROTEIN L22P, HMAL22, HL23
mol_id molecule chains synonym
20 RIBOSOMAL PROTEIN L23 T 50S RIBOSOMAL PROTEIN L23P, HMAL23, HL25, L21
mol_id molecule chains synonym
21 RIBOSOMAL PROTEIN L24 U 50S RIBOSOMAL PROTEIN L24P, HMAL24, HL16, HL15
mol_id molecule chains synonym
22 RIBOSOMAL PROTEIN L24E V 50S RIBOSOMAL PROTEIN L24E, HL21/HL22
mol_id molecule chains synonym
23 RIBOSOMAL PROTEIN L29 W 50S RIBOSOMAL PROTEIN L29P, HMAL29, HL33
mol_id molecule chains synonym
24 RIBOSOMAL PROTEIN L30 X 50S RIBOSOMAL PROTEIN L30P, HMAL30, HL20, HL16
mol_id molecule chains synonym
25 RIBOSOMAL PROTEIN L31E Y 50S RIBOSOMAL PROTEIN L31E, L34, HL30
mol_id molecule chains synonym
26 RIBOSOMAL PROTEIN L32E Z 50S RIBOSOMAL PROTEIN L32E, HL5
mol_id molecule chains
27 RIBOSOMAL PROTEIN L37Ae 1
mol_id molecule chains synonym
28 RIBOSOMAL PROTEIN L37E 2 50S RIBOSOMAL PROTEIN L37E, L35E
mol_id molecule chains synonym
29 RIBOSOMAL PROTEIN L39E 3 50S RIBOSOMAL PROTEINS L39E, HL39E, HL46E
mol_id molecule chains synonym
30 RIBOSOMAL PROTEIN L44E 4 50S RIBOSOMAL PROTEIN L44E, LA, HLA
Source :
mol_id organism_scientific
1 Haloarcula marismortui  (taxid:2238)
mol_id organism_scientific
2 Haloarcula marismortui  (taxid:2238)
mol_id organism_scientific
3 Haloarcula marismortui  (taxid:2238)
mol_id organism_scientific
4 Haloarcula marismortui  (taxid:2238)
mol_id organism_scientific
5 Haloarcula marismortui  (taxid:2238)
mol_id organism_scientific
6 Haloarcula marismortui  (taxid:2238)
mol_id organism_scientific
7 Haloarcula marismortui  (taxid:2238)
mol_id organism_scientific
8 Haloarcula marismortui  (taxid:2238)
mol_id organism_scientific
9 Haloarcula marismortui  (taxid:2238)
mol_id organism_scientific
10 Haloarcula marismortui  (taxid:2238)
mol_id organism_scientific
11 Haloarcula marismortui  (taxid:2238)
mol_id organism_scientific
12 Haloarcula marismortui  (taxid:2238)
mol_id organism_scientific
13 Haloarcula marismortui  (taxid:2238)
mol_id organism_scientific
14 Haloarcula marismortui  (taxid:2238)
mol_id organism_scientific
15 Haloarcula marismortui  (taxid:2238)
mol_id organism_scientific
16 Haloarcula marismortui  (taxid:2238)
mol_id organism_scientific
17 Haloarcula marismortui  (taxid:2238)
mol_id organism_scientific
18 Haloarcula marismortui  (taxid:2238)
mol_id organism_scientific
19 Haloarcula marismortui  (taxid:2238)
mol_id organism_scientific
20 Haloarcula marismortui  (taxid:2238)
mol_id organism_scientific
21 Haloarcula marismortui  (taxid:2238)
mol_id organism_scientific
22 Haloarcula marismortui  (taxid:2238)
mol_id organism_scientific
23 Haloarcula marismortui  (taxid:2238)
mol_id organism_scientific
24 Haloarcula marismortui  (taxid:2238)
mol_id organism_scientific
25 Haloarcula marismortui  (taxid:2238)
mol_id organism_scientific
26 Haloarcula marismortui  (taxid:2238)
mol_id organism_scientific
27 Haloarcula marismortui  (taxid:2238)
mol_id organism_scientific
28 Haloarcula marismortui  (taxid:2238)
mol_id organism_scientific
29 Haloarcula marismortui  (taxid:2238)
mol_id organism_scientific
30 Haloarcula marismortui  (taxid:2238)
Authors : Hansen, J.L., Ippolito, J.A., Ban, N., Nissen, P., Moore, P.B., Steitz, T.
Keywords : antibiotic, carbomycin A, macrolide, RIBOSOME
Exp. method : X-RAY DIFFRACTION ( 3.00 Å )
Citation :

The structures of four macrolide antibiotics bound to the large ribosomal subunit.

Hansen, J.L.,Ippolito, J.A.,Ban, N.  et al.
(2002)  Mol.Cell  10 : 117 - 128

PubMed: 12150912
DOI: 10.1016/S1097-2765(02)00570-1

The complete atomic structure of the large ribosomal subunit at 2.4 A resolution

Ban, N.,Nissen, P.,Hansen, J.  et al.
(2000)  Science  289 : 905 - 920

DOI: 10.1126/science.289.5481.905

The structural basis of ribosome activity in peptide bond synthesis

Nissen, P.,Hansen, J.,Ban, N.  et al.
(2000)  Science  289 : 920 - 930

DOI: 10.1126/science.289.5481.920

Reaction

Chain : C
UniProt : P20276 (RL2_HALMA)
Reaction : -
Chain : D
UniProt : P20279 (RL3_HALMA)
Reaction : -
Chain : E
UniProt : P12735 (RL4_HALMA)
Reaction : -
Chain : F
UniProt : P14124 (RL5_HALMA)
Reaction : -
Chain : G
UniProt : P14135 (RL6_HALMA)
Reaction : -
Chain : H
UniProt : P12743 (RL7A_HALMA)
Reaction : -
Chain : I
UniProt : P15825 (RL10_HALMA)
Reaction : -
Chain : K
UniProt : P29198 (RL13_HALMA)
Reaction : -
Chain : L
UniProt : P22450 (RL14_HALMA)
Reaction : -
Chain : M
UniProt : P12737 (RL15_HALMA)
Reaction : -
Chain : O
UniProt : P14123 (RL18_HALMA)
Reaction : -
Chain : P
UniProt : P12733 (RL18E_HALMA)
Reaction : -
Chain : Q
UniProt : P14119 (RL19E_HALMA)
Reaction : -
Chain : R
UniProt : P12734 (RL21_HALMA)
Reaction : -
Chain : S
UniProt : P10970 (RL22_HALMA)
Reaction : -
Chain : T
UniProt : P12732 (RL23_HALMA)
Reaction : -
Chain : U
UniProt : P10972 (RL24_HALMA)
Reaction : -
Chain : V
UniProt : P14116 (RL24E_HALMA)
Reaction : -
Chain : W
UniProt : P10971 (RL29_HALMA)
Reaction : -
Chain : X
UniProt : P14121 (RL30_HALMA)
Reaction : -
Chain : Y
UniProt : P18138 (RL31_HALMA)
Reaction : -
Chain : Z
UniProt : P12736 (RL32_HALMA)
Reaction : -
Chain : 2
UniProt : P32410 (RL37_HALMA)
Reaction : -
Chain : 3
UniProt : P22452 (RL39_HALMA)
Reaction : -
Chain : 4
UniProt : P32411 (RL44E_HALMA)
Reaction : -