Het-PDB Navi2 (PDB: 6B41)

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Ligands
Code	Name		Style	Show	Link
7PR	Praseodymium triacetate				PoSSuM
CJV	Methyl {(1s,2r)-2-[(S)-cyano[1-({1-[4-({1-[4-(dimethylamino)butanoyl]azetidin-3-yl}sulfonyl)phenyl]azetidin-3-yl}methyl)piperidin-4-yl](3-fluorophenyl)methyl]cyclopentyl}carbamate				PoSSuM

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Download interaction data: 6B41

Code :

6B41 PDBj RCSB PDB PDBe

Header :

PROTEIN BINDING/INHIBITOR

Title :

Menin bound to M-525

Release Data :

2018-01-24

Compound :

mol_id	molecule	chains
1	Menin	A

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Escherichia coli (taxid:562)
	gene: MEN1, SCG2

Authors :

Stuckey, J.A.

Keywords :

Covalent Inhibitor, MEN1 syndrome, leukemia, PROTEIN BINDING-INHIBITOR complex

Exp. method :

X-RAY DIFFRACTION ( 2.6100 Å )

Citation :

Design of the First-in-Class, Highly Potent Irreversible Inhibitor Targeting the Menin-MLL Protein-Protein Interaction.

Xu, S.,Aguilar, A.,Xu, T. et al.
(2018) Angew. Chem. Int. Ed. Engl. 57 : 1601 - 1605

PDB ID: 6B41