PDB ID: 5Q0C
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Code | Name | Style | Show | Link | |
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96G | N-[(5-bromo-1,3-thiazol-2-yl)carbamoyl]-5-(4-methoxyphenyl)thiophene-2-sulfonamide | PoSSuM | |||
FDP | 2,6-di-O-phosphono-beta-D-fructofuranose | PoSSuM |
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Download interaction data: 5Q0C
Structure summary
Code : | 5Q0C PDBj RCSB PDB PDBe | ||||||||||||
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Header : | HYDROLASE/HYDROLASE INHIBITOR | ||||||||||||
Title : | Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with the allosteric inhibitor 1-(5-bromo-1,3-thiazol-2-yl)-3-[5-(4-methoxyphenyl)thiophen-2-yl]sulfonylurea and with fructose-2,6-diphosphate | ||||||||||||
Release Data : | 2019-01-09 | ||||||||||||
Compound : |
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Authors : | Ruf, A., Joseph, C., Alker, A., Banner, D., Tetaz, T., Benz, J., Kuhn, B., Rudolph, M.G., Yang, H., Shao, C., Burley, S.K. | ||||||||||||
Keywords : | D3R docking, HYDROLASE-HYDROLASE INHIBITOR complex | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.4000 Å ) | ||||||||||||
Citation : |
Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with the allosteric inhibitor 1-(5-bromo-1,3-thiazol-2-yl)-3-[5-(4-methoxyphenyl)thiophen-2-yl]sulfonylurea and with f2,6p
Ruf, A.,Joseph, C.,Alker, A.
et al.
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Reaction
Chain : | A, B, C, D, E, F, G, H | ||||||||
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UniProt : | O00757 (F16P2_HUMAN) | ||||||||
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