Brand  (β version)

PDB ID: 4LY6

Hetero Atom Contents

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain: Hide other chain(s)

Ligands
Code Name Link
08T [[[(2r,3s,4r,5r)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxy-tris(fluoranyl)beryllium PoSSuM
ADP Adenosine-5'-diphosphate PoSSuM
MG Magnesium ion PoSSuM

Structure summary

Code : 4LY6   PDBj   RCSB PDB   PDBe
Header : TRANSCRIPTION REGULATOR
Title : Nucleotide-induced asymmetry within ATPase activator ring drives s54-RNAP interaction and ATP hydrolysis
Release Data : 2013-12-04
Compound :
mol_id molecule chains
1 Transcriptional regulator (NtrC family) A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T,U,V,W,X
fragment: UNP residues 121-387
Source :
mol_id organism_scientific expression_system
1 Aquifex aeolicus  (taxid:63363) Escherichia coli  (taxid:469008)
gene: aq_1117, ntrC1
expression_system_strain: BL2 (DE3) Rosetta
expression_system_vector_type: plasmid
expression_system_plasmid: pET21a
Authors : Sysoeva, T.A., Chowdhury, S., Guo, L., Nixon, B.T.
Keywords : AAA+ ATPase, bacterial enhancer binding protein, s54-dependent transcription activator, molecular machine, sigma54, s54-RNAP, TRANSCRIPTION REGULATOR
Exp. method : X-RAY DIFFRACTION ( 3.600 Å )
Citation :

Nucleotide-induced asymmetry within ATPase activator ring drives sigma 54-RNAP interaction and ATP hydrolysis.

Sysoeva, T.A.,Chowdhury, S.,Guo, L.  et al.
(2013)  Genes Dev.  27 : 2500 - 2511

PubMed: 24240239
DOI: 10.1101/gad.229385.113

Crystallization and preliminary X-ray analysis of a sigma54-dependent transcription activator NtrC1 from Aquifex aeolicus bound to ground state ATP analog

Sysoeva, T.A.,Yennawar, N.,Allaire, M.  et al.
To Be Published 

Reaction

Chain : A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X
UniProt : O67198 (No found in current UniProtKB/SwissProt)
Reaction : -