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Ligands
Code Name Style Show Link
MES 2-(N-morpholino)-ethanesulfonic acid
SO4 Sulfate ion
Non-standard Residues
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Glycosylation
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Code : 16GS   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : GLUTATHIONE S-TRANSFERASE P1-1 APO FORM 3
Release Data : 1999-01-13
Compound :
mol_id molecule chains synonym
1 GLUTATHIONE S-TRANSFERASE A,B GSTP1-1
ec: 2.5.1.18
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
cellular_location: CYTOSOL
gene: GSTP1
expression_system_gene: GSTP1
Authors : Oakley, A.J., Lo Bello, M., Ricci, G., Federici, G., Parker, M.W.
Keywords : TRANSFERASE, APOENZYME, DETOXIFICATION
Exp. method : X-RAY DIFFRACTION ( 1.90 Å )
Citation :

Evidence for an induced-fit mechanism operating in pi class glutathione transferases.

Oakley, A.J.,Lo Bello, M.,Ricci, G.  et al.
(1998)  Biochemistry  37 : 9912 - 9917

PubMed: 9665696
DOI: 10.1021/bi980323w

Chain : A, B
UniProt : P09211 (GSTP1_HUMAN)
Reaction: EC: Evidence:
Physiological Direction:
glutathione + RX = a halide anion + an S-substituted glutathione + H(+) 2.5.1.18 PubMed:1540159, PubMed:1567427, PubMed:8433974
left-to-right ECO:0000305
glutathione + prostaglandin J2 = prostaglandin J2-S-(R)- glutathione - PubMed:9084911
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glutathione + prostaglandin J2 = prostaglandin J2-S-(S)- glutathione - PubMed:9084911
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glutathione + prostaglandin A2 = prostaglandin A2-S-(S)- glutathione - PubMed:9084911
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11(S)-hydroxy-14(S),15(S)-epoxy-(5Z,8Z,12E)-eicosatrienoate + glutathione = (11S,15S)-dihydroxy-14(R)-S-glutathionyl-(5Z,8Z,12E)- eicosatrienoate - PubMed:21046276
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