ID	6F0AA	STANDARD;	PRT;	393	AA.
DT	CONVERTED FROM PDB (SEQRES) 6F0A
DE	Indoleamine 2,3-dioxygenase 1
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.260
CC	R-Factor	0.193
FT	#SUB	109	 119 	GLU	A	270	 280 	GLN	C	Protein	S	3
FT	#SUB	249	 259 	PHE	A	274	 284 	GLY	C	Protein	S	3
FT	#SUB	272	 282 	THR	A	287	 297 	ARG	C	Protein	S	4
FT	#SUB	280	 290 	GLN	A	280	 290 	GLN	C	Protein	S	1
FT	#SUB	280	 290 	GLN	A	284	 294 	ASP	C	Protein	S	2
FT	#SUB	283	 293 	GLN	A	287	 297 	ARG	C	Protein	S	4
FT	#SUB	284	 294 	ASP	A	280	 290 	GLN	C	Protein	S	6
FT	#SUB	287	 297 	ARG	A	272	 282 	THR	C	Protein	S	9
FT	#SUB	287	 297 	ARG	A	283	 293 	GLN	C	Protein	S	5
FT	#SUB	287	 297 	ARG	A	286	 296 	ARG	C	Protein	S	1
FT	#SUB	287	 297 	ARG	A	301	 311 	GLU	C	Protein	S	4
FT	#SUB	295	 305 	ASN	A	301	 311 	GLU	C	Protein	S	3
FT	#SUB	295	 305 	ASN	A	302	 312 	SER	C	Protein	A	9
FT	#SUB	298	 308 	CYS	A	298	 308 	CYS	C	Protein	A	7
FT	#SUB	299	 309 	SER	A	298	 308 	CYS	C	Protein	B	2
FT	#SUB	301	 311 	GLU	A	287	 297 	ARG	C	Protein	S	2
FT	#SUB	302	 312 	SER	A	295	 305 	ASN	C	Protein	A	8
FT	#HET	114	 124 	LEU	A	1	501 	C82	A	S	1	0
FT	#HET	115	 125 	VAL	A	1	501 	C82	A	B	2	0
FT	#HET	116	 126 	TYR	A	1	501 	C82	A	A	9	0
FT	#HET	116	 126 	TYR	A	3	503 	HEM	A	S	1	0
FT	#HET	119	 129 	CYS	A	1	501 	C82	A	S	7	2
FT	#HET	120	 130 	VAL	A	1	501 	C82	A	S	5	0
FT	#HET	153	 163 	PHE	A	1	501 	C82	A	S	13	0
FT	#HET	153	 163 	PHE	A	2	502 	ALA	A	S	1	0
FT	#HET	153	 163 	PHE	A	3	503 	HEM	A	S	5	0
FT	#HET	154	 164 	PHE	A	1	501 	C82	A	S	8	0
FT	#HET	157	 167 	SER	A	1	501 	C82	A	S	5	2
FT	#HET	157	 167 	SER	A	3	503 	HEM	A	A	4	0
FT	#HET	160	 170 	VAL	A	3	503 	HEM	A	S	4	0
FT	#HET	204	 214 	PHE	A	3	503 	HEM	A	S	10	0
FT	#HET	207	 217 	ILE	A	3	503 	HEM	A	S	1	0
FT	#HET	216	 226 	PHE	A	2	502 	ALA	A	S	3	0
FT	#HET	216	 226 	PHE	A	3	503 	HEM	A	S	3	0
FT	#HET	221	 231 	ARG	A	2	502 	ALA	A	S	10	2
FT	#HET	224	 234 	LEU	A	1	501 	C82	A	S	2	0
FT	#HET	252	 262 	GLY	A	1	501 	C82	A	B	9	0
FT	#HET	253	 263 	SER	A	1	501 	C82	A	A	18	1
FT	#HET	253	 263 	SER	A	3	503 	HEM	A	S	5	0
FT	#HET	254	 264 	ALA	A	1	501 	C82	A	A	14	1
FT	#HET	254	 264 	ALA	A	3	503 	HEM	A	A	14	0
FT	#HET	255	 265 	GLY	A	3	503 	HEM	A	B	3	0
FT	#HET	256	 266 	GLN	A	1	501 	C82	A	S	1	0
FT	#HET	260	 270 	PHE	A	3	503 	HEM	A	S	5	0
FT	#HET	333	 343 	ARG	A	3	503 	HEM	A	S	10	2
FT	#HET	336	 346 	HIS	A	3	503 	HEM	A	S	31	2
FT	#HET	339	 349 	ILE	A	3	503 	HEM	A	S	3	0
FT	#HET	340	 350 	VAL	A	3	503 	HEM	A	S	2	0
FT	#HET	343	 353 	TYR	A	3	503 	HEM	A	S	5	0
FT	#HET	344	 354 	ILE	A	2	502 	ALA	A	S	3	0
FT	#HET	344	 354 	ILE	A	3	503 	HEM	A	S	3	0
FT	#HET	368	 378 	GLY	A	2	502 	ALA	A	B	2	0
FT	#HET	368	 378 	GLY	A	3	503 	HEM	A	B	8	0
FT	#HET	369	 379 	THR	A	2	502 	ALA	A	A	11	3
FT	#HET	369	 379 	THR	A	3	503 	HEM	A	A	3	0
FT	#HET	370	 380 	GLY	A	3	503 	HEM	A	B	7	1
FT	#HET	371	 381 	GLY	A	3	503 	HEM	A	B	1	0
FT	#HET	372	 382 	THR	A	3	503 	HEM	A	A	8	2
FT	#HET	374	 384 	LEU	A	3	503 	HEM	A	S	2	0
FT	#HET	377	 387 	PHE	A	3	503 	HEM	A	S	4	0
FT	#HET	378	 388 	LEU	A	3	503 	HEM	A	S	4	0
FT	#HET	381	 391 	VAL	A	3	503 	HEM	A	S	2	0
FT	DISORDER	354	363
CC	SEQUENCE	383 AA (ATOM);
CC	ISKEYHIDEE VGFALPNPQE NLPDFYNDWM FIAKHLPDLI ESGQLRERVE KLNMLSIDHL
CC	TDHKSQRLAR LVLGCITMAY VWGKGHGDVR KVLPRNIAVP YCQLSKKLEL PPILVYADCV
CC	LANWKKKDPN KPLTYENMDV LFSFRDGDCS KGFFLVSLLV EIAAASAIKV IPTVFKAMQM
CC	QERDTLLKAL LEIASCLEKA LQVFHQIHDH VNPKAFFSVL RIYLSGWKGN PQLSDGLVYE
CC	GFWEDPKEFA GGSAGQSSVF QCFDVLLGIQ QTAGGGHAAQ FLQDMRRYMP PAHRNFLCSL
CC	ESNPSVREFV LSKGDAGLRE AYDACVKALV SLRSYHLQIV TKYILIPASQ QPKLEAKGTG
CC	GTDLMNFLKT VRSTTEKSLL KEG
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES ISKEYHIDEEVGFALPNPQENLPDFYNDWMFIAKHLPDLIESGQLRERVE
CC	ATOM   ISKEYHIDEEVGFALPNPQENLPDFYNDWMFIAKHLPDLIESGQLRERVE
CC	       **************************************************
CC	SEQRES KLNMLSIDHLTDHKSQRLARLVLGCITMAYVWGKGHGDVRKVLPRNIAVP
CC	ATOM   KLNMLSIDHLTDHKSQRLARLVLGCITMAYVWGKGHGDVRKVLPRNIAVP
CC	       **************************************************
CC	SEQRES YCQLSKKLELPPILVYADCVLANWKKKDPNKPLTYENMDVLFSFRDGDCS
CC	ATOM   YCQLSKKLELPPILVYADCVLANWKKKDPNKPLTYENMDVLFSFRDGDCS
CC	       **************************************************
CC	SEQRES KGFFLVSLLVEIAAASAIKVIPTVFKAMQMQERDTLLKALLEIASCLEKA
CC	ATOM   KGFFLVSLLVEIAAASAIKVIPTVFKAMQMQERDTLLKALLEIASCLEKA
CC	       **************************************************
CC	SEQRES LQVFHQIHDHVNPKAFFSVLRIYLSGWKGNPQLSDGLVYEGFWEDPKEFA
CC	ATOM   LQVFHQIHDHVNPKAFFSVLRIYLSGWKGNPQLSDGLVYEGFWEDPKEFA
CC	       **************************************************
CC	SEQRES GGSAGQSSVFQCFDVLLGIQQTAGGGHAAQFLQDMRRYMPPAHRNFLCSL
CC	ATOM   GGSAGQSSVFQCFDVLLGIQQTAGGGHAAQFLQDMRRYMPPAHRNFLCSL
CC	       **************************************************
CC	SEQRES ESNPSVREFVLSKGDAGLREAYDACVKALVSLRSYHLQIVTKYILIPASQ
CC	ATOM   ESNPSVREFVLSKGDAGLREAYDACVKALVSLRSYHLQIVTKYILIPASQ
CC	       **************************************************
CC	SEQRES QPKENKTSEDPSKLEAKGTGGTDLMNFLKTVRSTTEKSLLKEG
CC	ATOM   QPK----------LEAKGTGGTDLMNFLKTVRSTTEKSLLKEG
CC	       ***          ******************************
SQ	SEQUENCE	393 AA;      MW;         CN;
	ISKEYHIDEE VGFALPNPQE NLPDFYNDWM FIAKHLPDLI ESGQLRERVE KLNMLSIDHL
	TDHKSQRLAR LVLGCITMAY VWGKGHGDVR KVLPRNIAVP YCQLSKKLEL PPILVYADCV
	LANWKKKDPN KPLTYENMDV LFSFRDGDCS KGFFLVSLLV EIAAASAIKV IPTVFKAMQM
	QERDTLLKAL LEIASCLEKA LQVFHQIHDH VNPKAFFSVL RIYLSGWKGN PQLSDGLVYE
	GFWEDPKEFA GGSAGQSSVF QCFDVLLGIQ QTAGGGHAAQ FLQDMRRYMP PAHRNFLCSL
	ESNPSVREFV LSKGDAGLRE AYDACVKALV SLRSYHLQIV TKYILIPASQ QPKENKTSED
	PSKLEAKGTG GTDLMNFLKT VRSTTEKSLL KEG
//
ID	6F0AC	STANDARD;	PRT;	393	AA.
DT	CONVERTED FROM PDB (SEQRES) 6F0A
DE	Indoleamine 2,3-dioxygenase 1
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.260
CC	R-Factor	0.193
FT	#SUB	270	 280 	GLN	C	109	 119 	GLU	A	Protein	S	3
FT	#SUB	272	 282 	THR	C	287	 297 	ARG	A	Protein	A	9
FT	#SUB	274	 284 	GLY	C	249	 259 	PHE	A	Protein	B	3
FT	#SUB	280	 290 	GLN	C	280	 290 	GLN	A	Protein	S	1
FT	#SUB	280	 290 	GLN	C	284	 294 	ASP	A	Protein	S	6
FT	#SUB	283	 293 	GLN	C	287	 297 	ARG	A	Protein	S	5
FT	#SUB	284	 294 	ASP	C	280	 290 	GLN	A	Protein	S	2
FT	#SUB	286	 296 	ARG	C	287	 297 	ARG	A	Protein	S	1
FT	#SUB	287	 297 	ARG	C	272	 282 	THR	A	Protein	S	4
FT	#SUB	287	 297 	ARG	C	283	 293 	GLN	A	Protein	S	4
FT	#SUB	287	 297 	ARG	C	301	 311 	GLU	A	Protein	S	2
FT	#SUB	295	 305 	ASN	C	302	 312 	SER	A	Protein	S	8
FT	#SUB	298	 308 	CYS	C	298	 308 	CYS	A	Protein	S	7
FT	#SUB	298	 308 	CYS	C	299	 309 	SER	A	Protein	S	2
FT	#SUB	301	 311 	GLU	C	287	 297 	ARG	A	Protein	S	4
FT	#SUB	301	 311 	GLU	C	295	 305 	ASN	A	Protein	B	3
FT	#SUB	302	 312 	SER	C	295	 305 	ASN	A	Protein	A	9
FT	#HET	114	 124 	LEU	C	4	501 	C82	C	S	1	0
FT	#HET	115	 125 	VAL	C	4	501 	C82	C	B	2	0
FT	#HET	116	 126 	TYR	C	4	501 	C82	C	A	13	0
FT	#HET	116	 126 	TYR	C	6	503 	HEM	C	S	1	0
FT	#HET	119	 129 	CYS	C	4	501 	C82	C	S	6	2
FT	#HET	120	 130 	VAL	C	4	501 	C82	C	S	4	0
FT	#HET	153	 163 	PHE	C	4	501 	C82	C	S	14	0
FT	#HET	153	 163 	PHE	C	5	502 	ALA	C	S	2	0
FT	#HET	153	 163 	PHE	C	6	503 	HEM	C	S	7	0
FT	#HET	154	 164 	PHE	C	4	501 	C82	C	S	6	0
FT	#HET	157	 167 	SER	C	4	501 	C82	C	S	5	2
FT	#HET	157	 167 	SER	C	6	503 	HEM	C	A	5	0
FT	#HET	160	 170 	VAL	C	6	503 	HEM	C	S	2	0
FT	#HET	204	 214 	PHE	C	6	503 	HEM	C	S	13	0
FT	#HET	207	 217 	ILE	C	6	503 	HEM	C	S	2	0
FT	#HET	216	 226 	PHE	C	5	502 	ALA	C	S	2	0
FT	#HET	216	 226 	PHE	C	6	503 	HEM	C	S	6	0
FT	#HET	221	 231 	ARG	C	5	502 	ALA	C	S	10	2
FT	#HET	224	 234 	LEU	C	4	501 	C82	C	S	4	0
FT	#HET	252	 262 	GLY	C	4	501 	C82	C	B	8	0
FT	#HET	253	 263 	SER	C	4	501 	C82	C	A	19	1
FT	#HET	253	 263 	SER	C	5	502 	ALA	C	S	1	0
FT	#HET	253	 263 	SER	C	6	503 	HEM	C	S	4	0
FT	#HET	254	 264 	ALA	C	4	501 	C82	C	A	14	1
FT	#HET	254	 264 	ALA	C	6	503 	HEM	C	A	14	0
FT	#HET	255	 265 	GLY	C	6	503 	HEM	C	B	3	0
FT	#HET	256	 266 	GLN	C	4	501 	C82	C	S	1	0
FT	#HET	260	 270 	PHE	C	6	503 	HEM	C	S	3	0
FT	#HET	333	 343 	ARG	C	6	503 	HEM	C	S	10	2
FT	#HET	336	 346 	HIS	C	6	503 	HEM	C	S	29	2
FT	#HET	339	 349 	ILE	C	6	503 	HEM	C	S	2	0
FT	#HET	340	 350 	VAL	C	6	503 	HEM	C	S	1	0
FT	#HET	343	 353 	TYR	C	6	503 	HEM	C	S	4	0
FT	#HET	344	 354 	ILE	C	5	502 	ALA	C	S	2	0
FT	#HET	344	 354 	ILE	C	6	503 	HEM	C	S	3	0
FT	#HET	368	 378 	GLY	C	5	502 	ALA	C	B	2	0
FT	#HET	368	 378 	GLY	C	6	503 	HEM	C	B	8	0
FT	#HET	369	 379 	THR	C	5	502 	ALA	C	A	11	3
FT	#HET	369	 379 	THR	C	6	503 	HEM	C	A	4	0
FT	#HET	370	 380 	GLY	C	6	503 	HEM	C	B	7	1
FT	#HET	371	 381 	GLY	C	6	503 	HEM	C	B	1	0
FT	#HET	372	 382 	THR	C	6	503 	HEM	C	A	8	2
FT	#HET	374	 384 	LEU	C	6	503 	HEM	C	S	2	0
FT	#HET	377	 387 	PHE	C	6	503 	HEM	C	S	4	0
FT	#HET	378	 388 	LEU	C	6	503 	HEM	C	S	4	0
FT	#HET	381	 391 	VAL	C	6	503 	HEM	C	S	3	0
FT	DISORDER	353	363
FT	DISORDER	393	393
CC	SEQUENCE	381 AA (ATOM);
CC	ISKEYHIDEE VGFALPNPQE NLPDFYNDWM FIAKHLPDLI ESGQLRERVE KLNMLSIDHL
CC	TDHKSQRLAR LVLGCITMAY VWGKGHGDVR KVLPRNIAVP YCQLSKKLEL PPILVYADCV
CC	LANWKKKDPN KPLTYENMDV LFSFRDGDCS KGFFLVSLLV EIAAASAIKV IPTVFKAMQM
CC	QERDTLLKAL LEIASCLEKA LQVFHQIHDH VNPKAFFSVL RIYLSGWKGN PQLSDGLVYE
CC	GFWEDPKEFA GGSAGQSSVF QCFDVLLGIQ QTAGGGHAAQ FLQDMRRYMP PAHRNFLCSL
CC	ESNPSVREFV LSKGDAGLRE AYDACVKALV SLRSYHLQIV TKYILIPASQ QPLEAKGTGG
CC	TDLMNFLKTV RSTTEKSLLK E
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES ISKEYHIDEEVGFALPNPQENLPDFYNDWMFIAKHLPDLIESGQLRERVE
CC	ATOM   ISKEYHIDEEVGFALPNPQENLPDFYNDWMFIAKHLPDLIESGQLRERVE
CC	       **************************************************
CC	SEQRES KLNMLSIDHLTDHKSQRLARLVLGCITMAYVWGKGHGDVRKVLPRNIAVP
CC	ATOM   KLNMLSIDHLTDHKSQRLARLVLGCITMAYVWGKGHGDVRKVLPRNIAVP
CC	       **************************************************
CC	SEQRES YCQLSKKLELPPILVYADCVLANWKKKDPNKPLTYENMDVLFSFRDGDCS
CC	ATOM   YCQLSKKLELPPILVYADCVLANWKKKDPNKPLTYENMDVLFSFRDGDCS
CC	       **************************************************
CC	SEQRES KGFFLVSLLVEIAAASAIKVIPTVFKAMQMQERDTLLKALLEIASCLEKA
CC	ATOM   KGFFLVSLLVEIAAASAIKVIPTVFKAMQMQERDTLLKALLEIASCLEKA
CC	       **************************************************
CC	SEQRES LQVFHQIHDHVNPKAFFSVLRIYLSGWKGNPQLSDGLVYEGFWEDPKEFA
CC	ATOM   LQVFHQIHDHVNPKAFFSVLRIYLSGWKGNPQLSDGLVYEGFWEDPKEFA
CC	       **************************************************
CC	SEQRES GGSAGQSSVFQCFDVLLGIQQTAGGGHAAQFLQDMRRYMPPAHRNFLCSL
CC	ATOM   GGSAGQSSVFQCFDVLLGIQQTAGGGHAAQFLQDMRRYMPPAHRNFLCSL
CC	       **************************************************
CC	SEQRES ESNPSVREFVLSKGDAGLREAYDACVKALVSLRSYHLQIVTKYILIPASQ
CC	ATOM   ESNPSVREFVLSKGDAGLREAYDACVKALVSLRSYHLQIVTKYILIPASQ
CC	       **************************************************
CC	SEQRES QPKENKTSEDPSKLEAKGTGGTDLMNFLKTVRSTTEKSLLKEG
CC	ATOM   QP-----------LEAKGTGGTDLMNFLKTVRSTTEKSLLKE-
CC	       **           ***************************** 
SQ	SEQUENCE	393 AA;      MW;         CN;
	ISKEYHIDEE VGFALPNPQE NLPDFYNDWM FIAKHLPDLI ESGQLRERVE KLNMLSIDHL
	TDHKSQRLAR LVLGCITMAY VWGKGHGDVR KVLPRNIAVP YCQLSKKLEL PPILVYADCV
	LANWKKKDPN KPLTYENMDV LFSFRDGDCS KGFFLVSLLV EIAAASAIKV IPTVFKAMQM
	QERDTLLKAL LEIASCLEKA LQVFHQIHDH VNPKAFFSVL RIYLSGWKGN PQLSDGLVYE
	GFWEDPKEFA GGSAGQSSVF QCFDVLLGIQ QTAGGGHAAQ FLQDMRRYMP PAHRNFLCSL
	ESNPSVREFV LSKGDAGLRE AYDACVKALV SLRSYHLQIV TKYILIPASQ QPKENKTSED
	PSKLEAKGTG GTDLMNFLKT VRSTTEKSLL KEG
//